Type 1 diabetes (T1D) is characterized by selective autoimmune destruction of the insulin producing beta-cells in the islets of Langerhans. When the beta-cells are destroyed exogenous administration of insulin is necessary for maintenance of glucose homeostasis. Allogeneic islet transplantation has been used as a means to circumvent the need for insulin administration and has in some cases been ab

Single-photon emission computed tomography (SPECT) is important for imaging radioactivity distributions in vivo. Quantitative SPECT is limited due to attenuation and scatter contribution. Approximations such as constant attenuation and mono-exponential scatter functions will not be valid for non-homogeneous regions. A correction method is described where non-uniform density-maps are used in the at

Aerosol number concentrations in three size ranges (d(p) > 4, d(p) > 12, 18 less than or equal to, dp less than or equal to, 135 nm) and sulfur mass from impactor samples were collected over a total of about 120 sampling hours on 18 long-range commercial flights between the northern mid-latitudes and the equatorial region covering an altitude range between 8.8 and 11.2 km. The data were evaluated

This review discusses recent observations, in health and disease, on the release and distribution of plasma-derived molecules in the airway mucosa. Briefly, the new data on airway mucosal exudation mechanisms suggest that the protein systems of plasma contribute significantly to the mucosal biology, not only in injured airways but also in such mildly inflamed airways that lack oedema and exhibit n

A Discfilter with 10 and 18 mu m filter openings, respectively, was placed in parallel to a flotation plant for separation of biological flocs from a post-denitrifying Kaldnes Moving Bed (TM) Process, the last treatment step at the municipal wastewater treatment plant at Sjolunda, Malmo, Sweden. The effluent concentrations from the 10 and 18 mu m filter were 2-5 and 2-8 mg SS L-1, respectively, wh

This conference volume is structured by the five research areas of the Lund syna-gogue project “The Ancient Synagogue: Birthplace of Two World Religions,” funded by The Bank of Sweden Tercentenary Foundations, and by its time limit up to ca 200 C.E. The aim of the conference was to give an opportunity for young, emerging scholars to interact with some of the most prominent and established scholars

The group B Streptococcus, an important cause of invasive infections in the neonate, is classified into four major serotypes (Ia, Ib, II, and III) based on the structure of the polysaccharide capsule. Since the capsule is a known virulence factor, it has been extensively studied, in particular in type III strains, which cause the majority of invasive infections. Two cell surface proteins, alpha an

Popular Abstract in Swedish En mängd epidemiologiska studier har visat att fuktskador i bostaden eller på arbetsplatsen ökar risken för olika typer av hälsobesvär, t.ex. astmatiska och allergiska besvär. Exakt vad som emitteras och orsakar dessa symptom i fuktskadade byggnader är inte känt, men både kemiska och mikrobiologiska agens är misstänkta. Vidare finns behov av bättre metoder för att identIt has been shown in a large number of scientific studies that living or working in a building with mould and moisture damage increases the risk for asthmatic and allergic symptoms. However, there is a need to establish more valid methods to obtain a more nuanced picture of the wide range of different types of moisture related problems. Furthermore, the causal relationships and the biological mech

The exclusive H-2 (He-3, t)2p reaction has been studied at 2 GeV for energy transfers up to 500 MeV and triton angles up to 3.4degrees. The protons were measured in the large acceptance magnetic detector DIOGENE, in coincidence with the forward tritons detected in a dedicated magnetic arm. The energy transfer spectra extend well above the pion threshold. However, in the region of Delta excitation,

Popular Abstract in Swedish Identifiering av ärftlig äggstockscancer har stor klinisk relevans för att förhindra nya tumörer hos individen och i familjen. Möjligheten att förhindra bröstcancer i BRCA familjer genom kontrollprogram och profylaktisk kirurgi är välkänd, medan möjligheten att förhindra tarmcancer och livmodercancer i HNPCC familjer är mindre känd. Studierna i denna avhandling har kunnOvarian cancer is a leading cause of gynecological cancer death and in Sweden nearly 700 cases are diagnosed annually. Ovarian cancer has one of the highest frequencies of hereditary cancer. This thesis focuses on estimates of the contribution of hereditary breast and ovarian cancer (HBOC) and hereditary nonpolyposis colorectal cancer (HNPCC) to the development of ovarian cancer and investigates t

Popular Abstract in Swedish Denna studie är ämnad åt att undersöka joniseringsprocessen i gaser, både teoretiskt och experimentellt. Arbetet är speciellt riktat mot att utöka förståelsen för detta fenomen i förbränningsrummet av en förbränningsmotor. Den intensiva joniseringsprocessen som uppstår till följd av den antändande gnistan har studerats såväl som den svagare joniseringsprocessen som är rThe processes that govern the formation, existence and consumption of ions in gases have been studied both experimentally and theoretically. The aim of the work is targeted at increasing the understanding of these phenomena in the working gases inside an engine. Both the cause and the application of ionized gases inside the cylinder of a spark ignited (SI) engine has been studied. The spark disch

The ellipsoidally symmetric extension of Buda-Lund hydrodynamic model is shown here to yield a natural description of the pseudorapidity dependence of the elliptic flow upsilon(2)(eta)), as determined recently by the PHOBOS experiment for Au + Au collisions at root(S)NN = 130 and 200 GeV. With the same set of parameters, the Buda-Lund model describes also the transverse momentum dependence of upsi

Xanthine derivatives are known to accelerate mucociliary transport in the lower airways, probably by preventing degradation of cyclic adenosine monophosphate (cAMP) and thereby increasing its intracellular concentration. The purpose of this study was to investigate the effects of cAMP on mucociliary activity in the upper airways. The effect on the mucociliary activity in the rabbit maxillary sinus

Receptors for the neurotransmitter and neuroendocrine peptides, vasoactive intesinal peptide (VIP) and secretin, both belong to the Type B subfamily of G-protein-coupled receptors. This group is evolutionally as well as structurally distinct from the much larger Type A, or rhodopsin-type, subfamily. We have mapped the ligand-activating epitopes of the human VIP1 receptor by the use of hybrid recep