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Neurons have been neglected as cells with a major immune-regulatory function because they do not express major histocompatibility complex class II. Our data show that neurons are highly immune regulatory, having a crucial role in governing T-cell response and central nervous system (CNS) inflammation. Neurons induce the proliferation of activated CD4+ T cells through B7-CD28 and transforming growt
Structural and mechanical alterations during hypertrophy of the rat portal vein were investigated. Growth of the vessel was induced by a partial ligature of the vessel causing an increased transmural pressure. Vessel segments from animals kept with ligature for 1, 3, 5 and 7 days, were compared with vessels from sham-operated animals. Maximal active force and vessel cross-sectional area increased
Dual-broadband pure rotational coherent anti-Stokes Raman spectroscopy was investigated in terms of thermometry and species concentration measurement for studies of combustion. The modelling of rotational CARS spectra under conditions of high pressure at room temperature was investigated. Resonant terms of the Stokes (CSRS) type were found to have a significant effect on the intensity of the anti
This article outlines an experimental and numerical study on Poisson’s ratio of High Performance Concrete, HPC, subjected to air or sealed curing. Eight qualities of concrete (about 100 cylinders and 900 cubes) were studied, young and in the mature state. The concretes contained between 5 and 10% silica fume, and two concretes in addition contained air-entrainment. Parallel studies of strength and
This paper critically reviews reconstructions of cultural development in prehistoric Amazonia and argues for the primacy of regional and interregional exchange in generating the complex distributions of ethno-linguistic identities traced by linguists and archaeologists in the area. This approach requires an explicit abandonment of notions of migrating "peoples" in favor of modern anthropological u
This paper describes a simple tuner for a PID algorithm. The tuner i based on a simple method for determining the critical gain and the ultimate period.The controller settings are then determined by simple rules of the Ziegler-Nicholstype. The self-tuner is much simpler than algorithms proposed before.
Brain edema associated with severe chronic hypertension was studied in stroke-prone spontaneously hypertensive rats (SHRSP), 5 to 9 months of age. Blood-brain barrier (BBB) leakage sites and intracerebral spreading pathways for plasma proteins were delineated by an intravenously (i.v.) injected exogenous dye tracer (Evans blue), known to form a complex with albumin in blood, and by immunohistochem
In recent years the importance of strong brands has come very much into focus both among theoreticians and practitioners. In order to gain a better understanding of the nature of brand strength, I have chosen to analyse the branding process. The overriding aim of this analysis is to develop a theoretical framework and typology with which to facilitate our understanding of how powerful brands can b
Magnesium chelatase (EC 6.6.1.1) catalyses the insertion of magnesium into protoporphyrin IX, the first unique step of the chlorophyll biosynthetic pathway. The enzyme is composed of three different subunits of approximately 40, 70 and 140 kDa. In barley (Hordeum vulgare L.) the subunits are encoded by the genes Xantha-h, Xantha-g and Xantha-f. In the 1950s, eight induced xantha-f mutants were iso
A tegumental sensory organ is described in Derocheilocaris typica. It consists of sensory cells, the somata of which are situated in the rim of the central nervous system. They give rise to long dendrites, each of which transforms to one cilium. Three cilia surface in small pegs on the body. In the labrum there are seven peg sensilla with five and three with two cilia each that emerge in small por
The thesis comprises four independent research papers and a summary that focus on two related dimensions. The first dimension focuses on the understanding of the production of health. Particularly, the question is asked whether community's stock of social capital influence individual's health. The second dimension focuses on an attempt to understand the causes of socioeconomic health inequality (S
This paper compares the extraction effectiveness of six different commonly applied extraction techniques for the determination of PCBs in soil. The techniques included are Soxhlet, Soxtec, ultrasonication extraction, supercritical fluid extraction, microwave-assisted extraction and accelerated solvent extraction. For none of the techniques were the extraction conditions optimized, but instead the
Flow cytometric assessments of DNA ploidy status and the S-phase fraction (SPF) have been shown to yield prognostic information in breast cancer. The aim of the present investigation was to elucidate the reproducibility of results with regard to tumor DNA heterogeneity, and to ascertain whether the prognostic value of DNA measurements might be enhanced by analyzing two pieces of a tumor instead of
Popular Abstract in Swedish Denna avhandling behandlar statiska och dynamiska lagbeslutsproblem i både stokastiska och deterministiska ramverk. Lagproblemet är ett kooperativt spel, där ett antal spelare utgör ett lag som försöker optimera en given kostnad inducerad av omvärldens osäkerhet. Osäkerheten kan modelleras antingen som stokastisk, vilket ger upphov till det stokastiska lag problemet, elThis thesis considers static and dynamic team decision problems in both stochastic and deterministic settings. The team problem is a cooperative game, where a number of players make up a team that tries to optimize a given cost induced by the uncertainty of nature. The uncertainty is modeled as either stochastic, which gives the stochastic team problem, or modelled as deterministic where the team
