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Prediction of the development of islet autoantibodies through integration of environmental, genetic, and metabolic markers OR I G I N A L AR T I C L E Prediction of the development of islet autoantibodies through integration of environmental, genetic, and metabolic markers Bobbie-Jo M. Webb-Robertson1,2 | Lisa M. Bramer3 | Bryan A. Stanfill3 | Sarah M. Reehl3 | Ernesto S. Nakayasu1 | Thomas O. Met

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-06/121_MP193_Webb-Robertson_JDiabetes_2020%20(2).pdf - 2025-10-26

Plasma Metabolome and Circulating Vitamins Stratified Onset Age of an Initial Islet Autoantibody and Progression to Type 1 Diabetes: The TEDDY Study Plasma Metabolome and Circulating Vitamins Stratified Onset Age of an Initial Islet Autoantibody and Progression to Type 1 Diabetes: The TEDDY Study Qian Li,1 Xiang Liu,1 Jimin Yang,1 Iris Erlund,2 Åke Lernmark,3 William Hagopian,4 Marian Rewers,5 Jin

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-09/2020%20Li%20et%20al.%20Plasma%20metabolome%20Diabetes.pdf - 2025-10-26

An Age-Related Exponential Decline in the Risk of Multiple Islet Autoantibody Seroconversion During Childhood An Age-Related Exponential Decline in theRiskofMultiple Islet Autoantibody Seroconversion During Childhood https://doi.org/10.2337/dc20-2122 OBJECTIVE Islet autoimmunity develops before clinical type 1 diabetes and includes multiple and single autoantibody phenotypes. The objective was to

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/127_MP237_Bonifacio_Diab%20Care_2021.pdf - 2025-10-26

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/16%2006032016_679_16_Uusitalo_JFCA_2011.pdf - 2025-10-26

dc120111_pap 1..5 Performance of HbA1c as an Early Diagnostic Indicator of Type 1 Diabetes in Children and Youth KENDRA VEHIK, PHD 1 DAVID CUTHBERTSON, MS 1 DAVID BOULWARE, MS 1 CRAIG A. BEAM, PHD 1 HENRY RODRIGUEZ, MD 2 LAURENT LEGAULT, MD 3 MILA HYYTINEN, PHD 4 MARIAN J. REWERS, MD, PHD 5 DESMOND A. SCHATZ, MD 6 JEFFREY P. KRISCHER, PHD 1 THE TEDDY, TRIGR, DIABETES PREVENTION TRIAL-TYPE 1, AND T

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/20%2006032016_679_20_Vehik_Diab%20Care_2012.pdf - 2025-10-26

Pathogenesis of type 1 diabetes: lessons from natural history studies of highrisk individuals Ann. N.Y. Acad. Sci. ISSN 0077-8923 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES Issue: The Year in Diabetes and Obesity Pathogenesis of type 1 diabetes: lessons from natural history studies of high-risk individuals Natalie Nokoff1 and Marian Rewers1,2 1Department of Pediatrics, and 2Barbara Davis Center fo

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/24%2006032016_679_24_Nokoff_NYAS_2013.pdf - 2025-10-26

dmrr2427 557..567 Methods, quality control and specimen management in an international multicentre investigation of type 1 diabetes: TEDDY Kendra Vehik1* Steven W. Fiske1 Chad A. Logan1 Daniel Agardh2 Corrado M. Cilio2 William Hagopian3 Olli Simell4 Merja Roivainen5 Jin-Xiong She6 Thomas Briese7 Sami Oikarinen8 Heikki Hyoty8,9 Anette-G. Ziegler10 Marian Rewers11 Ake Lernmark2 Beena Akolkar12 Jeffr

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/27%2006032016_679_27_Vehik_DMRR_2013.pdf - 2025-10-26

untitled Public Health Nutrition: page 1 of 10 doi:10.1017/S1368980013003054 Infant feeding patterns in families with a diabetes history – observations from The Environmental Determinants of Diabetes in the Young (TEDDY) birth cohort study Sandra Hummel1,2,*, Kendra Vehik3, Ulla Uusitalo3, Wendy McLeod3, Carin Andrén Aronsson4, Nicole Frank5, Patricia Gesualdo5, Jimin Yang3, Jill M Norris6, Suvi

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/31%2006032016_679_31_Hummel_PHN_2013.pdf - 2025-10-26

Bol. Soc. Mat. Mexicana (3) Vol. 19, 2013 TWO APPLICATIONS OF PERMUTATION TESTS IN BIOSTASTICS LUIS LEÓN-NOVELO, KAISA M. KEMPPAINEN, ALEXANDRIA ARDISONNE, AUSTIN DAVIS-RICHARDSON, JENNIE FAGEN, KELSEY GANO, ERIC W. TRIPLETT, AND TEDDY STUDY GROUP ABSTRACT. We show two examples of how we answer biological questions by converting them into statistical hypothesis testing problems. We consider gene a

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/32%2006032016_679_32_LeonNovelo_Bol%20Soc%20Mat%20Mex_2013.pdf - 2025-10-26

Malawi Polyomavirus Is a Prevalent Human Virus That Interacts with Known Tumor Suppressors Christian Berrios,a,b Joonil Jung,c Blake Primi,d,e Michael Wang,f Chandrasekhar Pedamallu,a,c Fujiko Duke,a,c Christina Marcelus,a Jingwei Cheng,a,g Robert L. Garcea,d,e Matthew Meyerson,a,c,h James A. DeCaprio,a,b,g the TEDDY Study Group Department of Medical Oncology, Dana-Farber Cancer Institute, Boston,

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/38%2006032016_679_38_Berrios_JVirology_2014.pdf - 2025-10-26

Environmental factors in the etiology of type 1 diabetes, celiac disease, and narcolepsy Pediatric Diabetes 2016: 17(Suppl. 22): 65–72 doi: 10.1111/pedi.12390 All rights reserved © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. Pediatric Diabetes Review Article Environmental factors in the etiology of type 1 diabetes, celiac disease, and narcolepsy Lernmark Å. Environmental facto

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/59%2011042016_679_59_REVIEW_Lernmark_PedDiab_2016.pdf - 2025-10-26

A Swedish approach to the prevention of type 1 diabetes Pediatric Diabetes 2016: 17(Suppl. 22): 73–77 doi: 10.1111/pedi.12325 All rights reserved © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. Pediatric Diabetes Review Article A Swedish approach to the prevention of type 1 diabetes Elding Larsson H. A Swedish approach to the prevention of type 1 diabetes. Pediatric Diabetes 2016

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/60%2011042016_679_60_REVIEW_Larsson_PedDiab_2016.pdf - 2025-10-26

1Scientific RepoRts | 6:30828 | DOI: 10.1038/srep30828 www.nature.com/scientificreports A Comparison of Rule-based Analysis with Regression Methods in Understanding the Risk Factors for Study Withdrawal in a Pediatric Study Mona Haghighi1, Suzanne Bennett Johnson2, Xiaoning Qian3, Kristian F. Lynch4, Kendra Vehik4, Shuai Huang5 & The TEDDY Study Group† Regression models are extensively used in man

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/61%2010042016_679_61_MP99_Haghighi_SciRep_2016.pdf - 2025-10-26

First Infant Formula Type and Risk of Islet Autoimmunity in The Environmental Determinants of Diabetes in the Young (TEDDY) Study First Infant Formula Type and Risk of Islet Autoimmunity in The Environmental Determinants of Diabetes in the Young (TEDDY) Study DOI: 10.2337/dc16-1624 OBJECTIVE Studies on the introduction of infant formulas and its effect on the risk of islet autoimmunity and type 1

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/63%2001252019_679_063_MP102_HummelS_Diab%20Care_2017.pdf - 2025-10-26

PEDS_20162848.indd ARTICLEPEDIATRICS Volume 139 , number 3 , March 2017 :e 20162848 Psychological Manifestations of Celiac Disease Autoimmunity in Young Children Laura B. Smith, PhD, a Kristian F. Lynch, PhD, b Kalle Kurppa, MD, PhD, c Sibylle Koletzko, MD, PhD, d Jeffrey Krischer, PhD, a Edwin Liu, MD, e Suzanne Bennett Johnson, PhD, f Daniel Agardh, MD, PhD, g The TEDDY study group abstractBACKG

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/65%2001252019_679_065_MP124_Smith_Pediatrics_2017.pdf - 2025-10-26

Thomson REVIEW CURRENT OPINION Genetics and its potential to improve type 1 diabetes care Copyrig 1752-296X Copyright 2017 Wolte Stephen S. Rich Purpose of review The genetic basis of type 1 diabetes (T1D) is being characterized through DNA sequence variation and cell type specificity. This review discusses the current understanding of the genes and variants implicated in risk of T1D and how gene

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/67%2010262018_679_67_REVIEW_Rich_CurrOpinEndocrinDiabObes_2017.pdf - 2025-10-26

Thomson ORIGINAL ARTICLE: GASTROENTEROLOGY: CELIAC DISEASE Cesarean Section on the Risk of Celiac Disease in the Offspring: The Teddy Study Sibylle Koletzko, yHye-Seung Lee, zAndreas Beyerlein, §Carin A. Aronsson, zMichael Hummel, jjEdwin Liu, Ville Simell, #Kalle Kurppa, §Åke Lernmark, William Hagopian, yyMarian Rewers, zzJin-Xiong She, §§jjjjOlli Simell, §§Jorma Toppari, zAnette-G. Ziegler, yJe

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/73%2010262018_679_73_MP74_Koletzko_J%20Pediatr%20Gastroenterol%20Nutr_2017.pdf - 2025-10-26

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/75%2010262018_679_75_MP127_Kohler_ActaDiabetol_2017.pdf - 2025-10-26

Plasma 25-Hydroxyvitamin D Concentration and Risk of Islet Autoimmunity Plasma 25-Hydroxyvitamin D Concentration and Risk of Islet Autoimmunity Jill M. Norris,1 Hye-Seung Lee,2 Brittni Frederiksen,1 Iris Erlund,3 Ulla Uusitalo,2 Jimin Yang,2 Åke Lernmark,4 Olli Simell,5 Jorma Toppari,5,6 Marian Rewers,7 Anette-G. Ziegler,8 Jin-Xiong She,9 Suna Onengut-Gumuscu,10 Wei-Min Chen,10 Stephen S. Rich,10

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/82%2001252019_679_082_MP106a_Norris_Diabetes_2017.pdf - 2025-10-26

Model Assisted Statistics and Applications 12 (2017) 227–237 227 DOI 10.3233/MAS-170397 IOS Press A new framework for prediction and variable selection for uncommon events in a large prospective cohort study Hye-Seung Lee∗ and Jeffrey P. Krischer Health Informatics Institute, University of South Florida, Tampa, FL, USA Abstract. When prediction is a goal, validation utilizing data outside of the p

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/83%2010262018_679_83_MP194_Lee_MASA_2017.pdf - 2025-10-26