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The aim of this study was to describe prerequisites for online collaboration for user participation in co-design of online digital services as perceived by people with impairments and to develop requirements for how online collaboration should be designed to be accessible for all participants. An exploratory study was conducted in parallel to activities in two co-design projects. Researchers, acce
This paper introduces a novel diffusion-based method for learning representations from categorical data. Conditional diffusion models have demonstrated their potential to extract meaningful representations from input samples. However, they often struggle to yield versatile, multi-task information, limiting their adaptability to unforeseen tasks. To address this, we propose a cycle conditioning app
While fungal necromass is increasingly recognized as a major source of persistent carbon (C) in soils, the relative functional roles of bacteria and fungi in decomposing necromass are not fully resolved, and the processes that select for necromass decomposer communities from the broader soil microbial community are an emerging area of interest. In this study, we characterized the growth of 52 bact
ISSUES: Although alcohol consumption is linked to atrial fibrillation (AF), the relationship across different intake levels and between sexes remains unclear. This study presents the first network meta-analysis of prospective cohort studies bringing greater precision to these associations.APPROACH: A systematic review identified five meta-analyses on alcohol and AF risk. From these, 13 cohort stud
Solving partially observable Markov decision processes (POMDPs) typically requires reasoning about the values of exponentially many state beliefs. Towards practical performance, state-of-the-art solvers use value bounds to guide this reasoning. However, sound upper value bounds are often computationally expensive to compute, and there is a tradeoff between the tightness of such bounds and their co
Nanowires are promising structures for next-generation photonic devices due to their superior structural, optical, and electronic properties compared to thin films. In this study, unexpected electrostatic potential wells across the non-polar m-plane and at the core/shell interface in n-type GaN core/shell nanowires, grown via metal-organic vapor phase epitaxy, are reported. Using advanced electron
Ruthenium-based materials are promising alternatives to expensive platinum for the anodic hydrogen oxidation reaction (HOR) in anion exchange membrane fuel cells (AEMFCs), but face stability issues due to the strong oxophilicity. Here, an oxidation-resistant ruthenium multigrain catalyst is reported that exposes rich (10 (Formula presented.) 1) facets for high-performing HOR catalysis in alkaline
Inferring the causal structure underlying stochastic dynamical systems from observational data holds great promise in domains ranging from science and health to finance. Such processes can often be accurately modeled via stochastic differential equations (SDEs), which naturally imply causal relationships via 'which variables enter the differential of which other variables'. In this paper, we devel
Background: This study aimed to describe eating patterns among individuals with overweight and obesity and to investigate associations between eating patterns and anthropometric measures, including body mass index (BMI) and waist circumference, and blood pressure. Methods: This study enrolled a cohort of adults with overweight or obesity (n = 176) participating in a clinical trial focused on weigh
Introduction: Animation transfers human races into animals, serving as a prime site for speciesism and racism.Methods: Testing this observation on recent examples, our quantitative/qualitative study delves into a nine-year (2016-2024) span of Oscar-nominated animated feature and short films. We theorize how to make incisive, quantitative/qualitative, balanced trans-species intersectionality the fo
Introduction: Oral dopaminergic treatment is the cornerstone of Parkinson’s disease (PD) management. However, progressive shortening of oral levodopa’s effect, along with the limited efficacy of enzyme inhibitors and dopamine agonists, does not allow to adequately control motor and non-motor complications characterizing advanced PD. At this stage, device-aided therapies (DATs), including infusion
Obstructive sleep apnea (OSA) has been hypothesised to promote cancer via intermittent hypoxia, and assessing what happens when OSA is controlled by continuous positive airway pressure (CPAP) may provide valuable insight. We conducted a meta-analysis of three randomised controlled trials (SAVE, RICCADSA, ISAACC) assessing cancer incidence from adverse event data on neoplasms among OSA patients ran
Alzheimer’s disease (AD) is the most common neurodegenerative disorder, affecting millions worldwide. The clinical presentation of AD is heterogenous and often complicated by the presence of multiple co-pathologies, which can overlap with features of other neurodegenerative disorders, underscoring the need for tools to aid accurate and timely diagnosis. Biomarkers for AD span multiple modalities a
Objectives ‒ The STarT Back screening Tool (SBT) captures patients with low back pain (LBP) at risk of worse prognosis. However, the SBT does not include assessment of multisite and chronic widespread pain (MS-CWP). The aim was to study the differences in prognostic factors in patients with LBP classified according to SBT or SBT in combination with MS-CWP, and the 1-year outcome regarding visits t
Imaging the orientations of crystallites in bone requires the usage of synchrotron X-ray radiation, which is a limited resource for researchers. Thus scans have historically been limited to either small regions or few samples. In the present study, we scan 16 full frontal cross sections of mouse femora. This makes it possible to study structure, orientation, and composition, statistically across m
