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Oligomers are transient toxic species in amyloidoses such as Alzheimer's disease. The binding of oligomers by human chaperone proteins has been inferred from the lack of detectable interactions with monomeric amyloid proteins and delay of fibril formation at sub-stoichiometric chaperone to monomer molar ratios. In this study, we provide direct experimental evidence for the binding of the human cha
The Large Magellanic Cloud (LMC) and Small Magellanic Cloud (SMC) are the Milky Way’s nearest interacting galaxy pair, offering a unique laboratory for studying tidal effects on galactic disks. Despite extensive survey efforts, the 3D geometry of the Magellanic Clouds, particularly the putative warp of the LMC, remains poorly constrained due to incompleteness in their crowded centers and the low s
The aim of this work is to integrate a machine-learning (ML)-based meta-model into a conventional structural vibration model in a componentwise manner using dynamic substructuring. In dynamic substructuring, the finite element (FE) method is one of the popular ways of modeling substructures. In this study, we theoretically examine dynamic substructuring formulations for cases where an ML-based met
Context: Even within the physiological range, serum calcium (sCa++) may influence vascular tone and blood pressure (BP); however, the potential modulatory role of dietary calcium intake remains unclear. Objective: To investigate the association between sCa2+ and BP (including central BP) and to assess whether calcium intake affects this relationship. Methods: sCa2+ was measured in patients referre
Bygg- och fastighetssektorn står för en betydande del av Sveriges och EU:s energianvändning och klimatpåverkan. Samtidigt ökar behovet av energieffektiva bostäder i takt med befolkningstillväxt och ökade krav på klimatanpassning och hållbarhet. Energieffektivisering inom byggnadssektorn lyfts därför fram som en central åtgärd för att minska energianvändning och växthusgasutsläpp. Utöver tekniska lBygg- och fastighetssektorn står för en betydande del av Sveriges och EU:s energianvändning och klimatpåverkan. Samtidigt ökar behovet av energieffektiva bostädeThis thesis investigates how window airing behavior affects indoor environment and energy use in residential buildings. The study focuses on the relationship between airing, indoor temperature, CO₂ concentration, and how different represen
This study investigates Scanian Swedes’ dialect identification ability of seven Swedish regional dialects. Particularly, the study aims to find out whether or not the scientific division of Swedish dialect regions more or less overlap with actual speakers’ ability to differentiate between dialects. It also investigates some idiosyncratic participant variables that affect dialect identification abi
Various factors may impact the process of reading. The depth of the orthography influences the reading strategy for readers of shallow and deep orthographies because the complexity of the mapping between graphemes and phonemes increases with depth. In this thesis, reading comprehension in Danish, considered a deep orthography, is examined. While phonological awareness is commonly recognized as an
Flowing curls, serpentine tresses, and golden or darkened locks haunt fin-de-siècle Gothic fiction, where feminine hair emerges as both an object of aesthetic fascination and a mythic site of seduction, monstrosity, and feminine excess. This thesis examines the representation of feminine hair in fin-de-siècle Gothic fiction, focusing on how hair functions as a site of cultural anxieties surroundin
TFNP studies the complexity of total, verifiable search problems, and represents the first layer of the total function polynomial hierarchy (TFPH). Recently, problems in higher levels of the TFPH have gained significant attention, partly due to their close connection to circuit lower bounds. However, very little is known about the relationships between problems in levels of the hierarchy beyond TF
The complexity class PPP contains all total search problems many-one reducible to the Pigeon problem, where we are given a succinct encoding of a function mapping n+1 pigeons to n holes, and must output two pigeons that collide in a hole. PPP is one of the “original five” syntactically-defined subclasses of TFNP, and has been extensively studied due to the strong connections between its defining p
In their seminal work, Atserias et al. and independently Pipatsrisawat and Darwiche in 2009 showed that CDCL solvers can simulate resolution proofs with polynomial overhead. However, previous work does not address the tightness of the simulation, i.e., the question of how large this overhead needs to be. In this paper, we address this question by focusing on an important property of proofs generat
We study the problem of testing whether a function f:R^n→R is a polynomial of degree at most d in the distribution-free testing model. Here, the distance between functions is measured with respect to an unknown distribution D over Rn from which we can draw samples. In contrast to previous work, we do not assume that D has finite support.We design a tester that given query access to f, and sample a
What is the effect of foreign events on ideas and discourses at the national level? This paper argues that a foreign event may set in motion an ideational momentum that gives positive attention to certain ideas, strengthening the credibility of political actors that hold these ideas, and hurting the credibility of actors promoting competing ideas. Based on a regression discontinuity design and qua
We consider two-dimensional irrotational steady gravity waves and derive new explicit analytical bounds for the velocity field and the slope of the free surface. Using an auxiliary function tailored to the streamfunction formulation, we obtain an explicit exponential decay estimate which is optimal for linear waves. The same method yields a new slope estimate that improves existing bounds in the m
Traceability in the dairy supply chain helps ensure high transparency, quality assurance, and regulatory compliance. At the same time, the implementation of traceability in the dairy sector faces several challenges; therefore, this paper examines the factors influencing the implementation of AI-enabled traceability in the Indian dairy industry. The Fuzzy-Decision-Making Trial and Evaluation Labora
This paper presents NMCu-CNN, a near-memory computing (NMC) co-processor for the hardware acceleration of convolutional neural networks (CNNs) on a low-power, flexible MCU platform. The scalable architecture and the selected platform enable adaptability to the rapidly evolving Edge AIoT landscape, where energy and performance requirements are constrained. Application-tailored NMC units, equipped w
For this episode of “Global Governance Beyond Neoliberalism”, we had the pleasure of engaging with Ian Manners, professor of political science at Lund University. Manners has decades of experience in teaching in Denmark, Britain and Sweden and is widely known for his work on normative power, European integration, and global politics. His research explores how values, identities, and political norm
'Does the EU Still Have Normative Power? Rethinking Europe in a Time of Crisis' brought to you by the European Dialogue.What does it mean for the European Union to have “normative power” in today’s world, and does that idea still hold?In this episode recorded in February 2026, Professor Ian Manners revisits the concept he famously coined and reflects on how the EU’s global role is being reshaped i
In this interview, Professor Ian Manners of the University of Lund revisits the concept he helped define - Normative Power approach - to examine what it really means to think of the EU as a living, evolving political project rather than a fixed set of institutions. He explores which values the EU genuinely embodies on the world stage, beyond its own rhetoric, and how far these values hold up under
