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Background: Motion sickness (MS) is a common complaint during most modes of travel. Several medications can be used to treat MS but are often accompanied by side-effects. Objective: To assess whether performing the Valsalva manoeuvre can influence the subjective feeling of MS in healthy individuals. Methods: We included 16 healthy participants (4 female) that underwent two sessions of MS induction
Increasing frequency and intensity of droughts threaten grassland ecosystems. Semi-natural grasslands vary in age from ancient to younger sites established on former arable land. While species richness and composition are known to affect drought resilience, little is known about how grassland age shapes drought responses through eco-evolutionary processes at the plant population level. We explored
Since its discovery in 1872, the grave at Öremölla in southern Scania, containing a cremated male with a Roman cauldron and other drinking utensils, has been considered one of the richest graves in Scania from the Roman Iron Age. The cauldron is particularly noteworthy, since it has been modified in an intricate way; the original handle has been removed and replaced with ring handles, and the hand
INTRODUCTION: Sex differences in symptomatic carotid artery stenosis have been reported with conflicting results, with knowledge gaps regarding the degree of carotid stenosis, management and preoperative ischaemic events. This study aimed to determine sex differences in symptomatic carotid artery stenosis prior to undergoing carotid endarterectomy (CEA) or carotid artery stenting (CAS).PATIENTS AN
Over one third of the population develops cancer during their life-time and stroke associated with malignancy accounts for 10% of all hospitalized patients. With and improved survival and better life quality of patients with cancer, cancer related stroke is likely to increase. It is crucial to early diagnose an underlying malignancy to optimize treatment. It is known that a major mechanism is canc
Ion clustering has been proposed as a mechanism leading to the peculiar "anomalous underscreening" phenomenon seen for electrostatic interactions between charged surfaces immersed in concentrated electrolytes. These interactions have been measured using the Surface Force Apparatus, according to which there are strong repulsive interactions between like-charged surfaces, with a range that increases
Strengthening international climate governance is seen as pivotal for advancing the Sustainable Development Goals (SDGs). However, a systematic understanding of their dynamic interactions remains limited. Given the strong interconnections among the SDGs, climate governance policies designed to advance one goal can significantly influence progress on others, highlighting the need for an integrated
This thesis consists of three self-contained papers that examine how information and ideologies serve as coordinating forces during episodes of political and social transformation.The first paper studies how shifts in public sentiment can trigger mass mobilization, using the Finnish Civil War of 1918 as a natural experiment. I show that the abrupt abolition of Russian imperial censorship in 1917 p
Circular supply chains (CSCs) depend on enhanced supply chain visibility (SCV) to track and manage resource flows and thereby enable efficient decision-making. Despite confronting silo mentalities, fragmented information, technological barriers, resistance to change, and a lack of standardization, data sharing remains crucial for SCV and circularity. In this study, following the Delphi method, 22
De 6-åriga läkarprogrammen ger legitimation och förskrivningsrätt direkt efter examen.En nationell arbetsgrupp har tagit fram förslag till hur läkarstudenter under grundutbildningen ska ges möjligheter att träna på läkemedelsbehandling samt hur lärosätena ska kunna examinera kunskaper och färdigheter.Gruppen föreslår ökad tydlighet i kedjan lärandemål–aktiviteter–examination, färdighetsträning i d
This paper analyses how large Swedish firms and financial institutions integrate climate change and biodiversity into their business strategies and governance structures. Using unique 2022 and 2023 survey data and logistic probability models, we examine how internal and external factors shape early responses to the EU Taxonomy and the CSRD. Our findings confirm that the integration of climate chanThis paper analyses how large Swedish firms and financial institutions integrate climate change and biodiversity into their business strategies and governance structures. Using unique 2022 and 2023 survey data and logistic probability models, we examine how internal and external factors shape early responses to the EU Taxonomy and the CSRD. Our findings confirm that the integration of climate chan
SammanfattningKapitel 5 behandlar en ny cancerbehandlings strategi som kombinerar: Joniserande strålning med Elektrisk pulsterapi (elektroporation).Målet är att förbättra naturförstörelsen, samtidigt som immunförsvaret stimuleras.Initiala Prekliniska fynd (djurstudier)Experiment på råttor med gliomtumör testade effekten av enbart strålning(RAD), enbart elektriska pulser(PEF) och en kombination av
Sammanfattning av ver. 2 Nästa generation av tumörbehandling? Pre-kirurgisk intermittent strålbehandling kombinerad med immunterapi (PSiRIT).Grundtanken är att använda strålningens läkande krafter genom att med en låg dos strålning på 6 till 8 Gy före operation, kombinerad med immunstimulerande behandling aktivera kroppens immunförsvar mot tumören, förbättra behandlingsresultat och potentiellt upp
Epigenome-wide studies of pancreatic islets provide valuable insights into type 2 diabetes (T2D) but lack methylomes from individual cell types. Here we show changes to alpha and beta cell-specific methylomes and transcriptomes from people with or without T2D, using whole-genome bisulfite sequencing and RNA sequencing. We discover 22,544 differentially methylated regions annotated to 7,975 genes i
ABSTRACT Background Posterior fossa tumours (PFT), among the most common childhood brain tumours, place children at risk of speech, language, and communication difficulties, often described in relation to cerebellar mutism syndrome (CMS) but also seen in children without mutism. Narrative ability refers to the capacity to understand, create, and share stories. Narratives can be analysed at the macBackgroundPosterior fossa tumours (PFT), among the most common childhood brain tumours, place children at risk of speech, language, and communication difficulties, often described in relation to cerebellar mutism syndrome (CMS) but also seen in children without mutism. Narrative ability refers to the capacity to understand, create, and share stories. Narratives can be analysed at the macrostructur
Malaria caused by Plasmodium falciparum (P. falciparum) remains a major cause of morbidity and mortality, particularly in sub-Saharan Africa. Immunity develops gradually after repeated exposure and is largely mediated by antibodies, yet the mechanisms regulating the development and function of humoral immunity, including the roles of B-cell subsets and inflammatory mediators, remain incompletely u
This dissertation investigates how the ageing process affected income, work, and family structures, and how broader economic forces shaped the living standards of older adults in 19th-century Stockholm. It situates individual life cycles within the wider context of 19th-century economic and demographic change. Through an integrated micro-historical analysis of household earnings, savings, poverty
The expansion of e-commerce and the consequent spatial changes raise questions about how accessibility and liveability for older people is considered in increasingly ageing societies. The aim of this article is to enhance the understanding of how digitally literate older people perceive e-commerce as a tool to accommodate their needs. The study therefore poses the question: How do digitally litera
