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To determine the functions of fibromodulin (Fmod), a small leucine-rich keratan sulfate proteoglycan in tooth formation, we investigated the distribution of Fmod in dental tissues by immunohistochemistry and characterized the dental phenotype of 1-day-old Fmod-deficient mice using light and transmission electron microscopy. Immunohistochemistry was also used to compare the relative protein express

To test the hypothesis that GH-induced insulin resistance is mediated by an increase in FFA levels we assessed insulin sensitivity after inhibiting the increase in FFA by a nicotine acid derivative, Acipimox, in nine GH-deficient adults receiving GH replacement therapy. The patients received in a double blind fashion either Acipimox (500 mg) or placebo before a 2-h euglycemic (plasma glucose, 5.5

Preventive actions targeting community-dwelling frail older people will be increasingly important with the growing number of very old and thereby also frail older people. This study aimed to explore and summarize the empirical literature on recent studies of case/care management interventions for community-dwelling frail older people and especially with regard to the content of the interventions a

Abstract in UndeterminedThe effects of harvesting on the long-term mass balances of calcium (Ca), magnesium (Mg) and potassium (K) were evaluated on a regional level in Sweden. A new high-resolution weathering database was used together with estimates of total deposition, losses through harvest and leaching. Estimates were made for pine and spruce separately and for two harvesting intensity scenar

Abstract in Danish At indisk landbrug stik imod forventningerne har udviklet sig positivt efter selvstændigheden, er ikke blot et resultat af den grønne revolution. Det skyldes i lige så høj grad statens aktive indblanding og ikke mindst bøndernes kamp for jordreformer, fremgår det af denne analyse af sociale bevægelsers betydning for indiske landbrugsudvikling. Nye producentorienterede bondebevæg

This report discusses control of dissolved oxygen in a bioreactor where the oxygen supply is manipulated using the stirrer speed. In batch and fed-batch cultivations the operating conditions change significantly which may cause tuning problems. Analysis using a linearized process model shows that the process dynamics is mainly affected by changes in the volumetric oxygen transfer coefficient $K_La

The first results from a series of experiments focused on the study of the internal structure of nuclei at the extremes of N:Z ratio using isomer spectroscopy are reported. These experiments represent the first of the Stopped Beam section of the Rare Isotopes Investigations at GSI (RISING) project. Exotic nuclei were synthesized using relativistic projectile fragmentation of similar to 500 -> 1000

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The purpose of the paper is to discuss whether a particular robot can be said to have an 'inner world', something that can be taken to be a critical feature of consciousness. It has previously been argued that the mechanism underlying the appearance of an inner world in humans is an ability of our brains to simulate behaviour and perception. A robot has previously been designed in which perception

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors regulating the expression of genes involved in lipid and glucose metabolism in a complex and to some extent unknown manner. Our aim was to study the impact of different factors on PPAR delta mRNA expression in human skeletal muscle on one side, and the impact of PPAR delta mRNA expression on these factors, including glucose

Screening women for lower genital tract infection with Chlamydia trachomatis is important in the prevention of pelvic inflammatory disease, ectopic pregnancy and infertility. This systematic review aims to state clearly which of the available diagnostic tests for the detection of C. trachomatis would be most effective in terms of clinical effectiveness. The review included all studies published fr

Abstract in French Au cours de la preacutesente eacutetude nous faisons la description systeacutematique, du point de vue neurolinguistique et interactionnel, de deux enfants de sexe feacuteminin souffrant de deacutesordres seacutemantico-pragmatiques, ces derniers formant un sous-groupe au sein du groupe des deacutesordres speacutecifiques les plus aigus du deacuteveloppement du langage. Nous avaIn the present study we provide thorough descriptions of two children with a semantic-pragmatic disorder, a subgroup within the group of specific and severe developmental language disorders, from a neurolinguistic and interactional perspective. We argue that the pragmatic problems, at least in these two girls, are most probably secondary to their semantic'conceptual deficit. If sufficient contextu