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OBJECTIVE: To examine whether iron intake and genetically determined iron overload interact in predisposing to the development of childhood islet autoimmunity (IA) and type 1 diabetes (T1D).RESEARCH DESIGN AND METHODS: In The Environmental Determinants of Diabetes in the Young (TEDDY) study, 7,770 genetically high-risk children were followed from birth until the development of IA and progression t
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Open Source Software (OSS) has become an increasingly important knowledge asset in modern economies. However, the economic impact of OSS on countries’ GDP is ambivalent due to its public good character. Using a cross-country panel from 2000 to 2018, including 25 of the largest EU countries plus the USA, Japan, Korea, Canada, China, Norway, and Switzerland, matching OSS commits to GitHub to macroec
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In this perspective article, we call for more engagement with the unexplored politics of residual emissions. Residual emissions are those emissions that remain at the point of net zero, despite abatement efforts. Unlike carbon dioxide removal, which has been the focus of a lively research and policy debate, the notion of residual emissions remains relatively unexplored so far. With the mainstreami
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Extended Reality (XR) serves as a broad term that encompasses several immersive technologies, including Augmented Reality (AR), Mixed Reality (MR), and Virtual Reality (VR). Currently, most XR devices are connected by cables, which restrict user mobility and negatively impact the overall Quality of Experience (QoE) for users. XR devices face limitations not only in terms of connectivity but also i
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Background: Various plasma phosphorylated tau species have been shown to be associated with amyloid-β (Aβ) PET and Tau PET in Alzheimer’s disease (AD), but whether APOE ε4 affects the interaction between glial fibrillary acidic protein (GFAP) and phosphorylated tau (pTau), and whether a three-way interaction exists among APOE ε4, GFAP, and pTau that influences AD progression remain unclear. Method