Filtyp
The dystrophin-glycoprotein complex (DGC) is composed of peripheral and integral membrane proteins at the muscle cell membrane that link the extracellular matrix with the intracellular cytoskeleton. While it is well established that genetic mutations that disrupt the structural integrity of the DGC result in numerous muscular dystrophies, the 3D structure of the complex has remained elusive. Two r
As the total cost of renewable electricity falls lower than the price of fossil fuel, not only can electricity be used to replace fossil fuels using batteries in vehicles but it can also be used to produce fuels. This makes it possible to replace fuels in sectors not easily directly electrified. It also provides new ways of balancing the electricity system. When renewable electricity is cheap a lo
This chapter critically examines a number of ethical dilemmas at stake for professionals working with refugee children and families in Denmark within the field of early childhood education. While national guidelines promote diversity by framing cultural differences as valuable resources, integration policies often result in efforts aimed at assimilation. The chapter explores how everyday ethical j
This article examines, firstly, how legal and safe pathways, in particular resettlement and humanitarian corridors, are regulated in French legislation and how they are implemented in practice, and secondly, the implications of this regulation and implementation for the promise of legal pathways to offer regular entry for asylum purposes. Using a legal and policy approach, our research shows that
Reactions of LXYL17 or LXYL18 (LXYL17 = α,α′-bis[((1-methyl-2-benzimidazolyl)methyl)-N-(6-methyl-2-pyridylmethyl)-amino]-m-xylene; LXYL18 = α,α′-bis[((1-methyl-2-benzimi-dazolyl)-methyl)-N-(2-pyridylethyl)-amino]-m-xylene) with [Cu(MeCN)4](ClO4) in CH2Cl2 at 298 K, subsequent exposure to dioxygen, and work-up from MeCN–MeOH, led to [CuII2(LXYL17)(μ-OMe)2](ClO4)2•0·5H2O (1) and [CuII2(L XYL18)(μ-OM
Introduction: The hepatic cytochrome P450 system includes the polymorphic CYP2D6 gene. CYP2D6 ultra rapid metabolizers (UMs) were 10-fold more common in suicide victims than in the general population in a previous study. The aim of this study was to investigate if the occurrence of the CYP2D6 UM genotype differs between subjects with and without previous suicide attempt in patients treated for dep
In order to understand and manipulate biological function at the molecular level, access to high-resolution structures of biological macromolecules is essential, as structure is intimately linked to function. The two main experimental techniques that can achieve atomic, or near-atomic, resolution are crystallography and electron microscopy. Unfortunately, the experimental data alone is typically n
The complexity of modern healthcare continues to evolve, emphasizing the need for comprehensive collaboration among professionals from diverse backgrounds, patients, and their families to integrate care. Multidisciplinary team meetings (MDTMs) have emerged as an opportunity to advance interprofessional collaborative practice. However, despite their growing prevalence in clinical and educational co
How may changes in musicians’ experience of time influence their impressions of hav- ing conscious intentions during musical activity? In this essay I will present and discuss an autoethnographic account of how an exceptionally heightened awareness of time during musical improvisation may be connected to a heightened awareness of one’s own mental activity, particularly of speedy internal deliberatHow may changes in musicians’ experience of time influence their impressions of having conscious intentions during musical activity? In this essay I will present and discuss an autoethnographic account of how an exceptionally heightened awareness of time during musical improvisation may be connected to a heightened awareness of one’s own mental activity, particularly of speedy internal deliberativ
Speech signal decoding relies on both cognitive performance and the ability to perceive the acoustic signal in sufficient detail. In everyday communication, natural speech is often rapid, spatially and spectrally complex, and accompanied by noise. The brain generates predictions to cope with the complex nature of the auditory signal in speech perception. Anticipatory coarticulation is a natural pa
(conference presentation at the "Svensk gnosis genom tiderna"/"Swedish Gnosis through the ages" conference, Stockholm, April 2025)
BACKGROUND: The predictive value of atrial conduction abnormalities, reflected by P-wave indices (PWI), and their association with biomarkers signaling fibrosis for the development of atrial fibrillation (AF) in patients with heart failure (HF) remains underexplored.OBJECTIVE: We aim to investigate the associations between PWI, fibrosis biomarkers, and the risk of incident AF in patients with HF.M
The South-to-North Water Diversion Project (SNWDP), the world’s largest water transfer initiative, is designed to address northern China’s acute water scarcity by diverting approximately 45 km3 of water annually from the south through three major routes, with completion targeted for 2050. This review demonstrates that the SNWDP has already improved water security for over 150 million people, stabi
The invention pertains to a process for preparing a random co- poly(hydroxycarbonate) comprising reacting a 6-membered di-cyclic carbonate with a polyol, or a monohydric alcohol, via a ring-opening polymerization (ROP) by catalytic control for carbonate unit formation, in the presence of a catalyst, through a ring- opening polymerization reaction. Also, the invention pertains to a random co- poly(
The invention pertains to a process for preparing a random co-poly(urethane-carbonate) comprising reacting a 6-membered di-cyclic carbonate with a polyamine via a ring- opening polymerization (ROP) by catalytic control for carbonate unit formation, in the presence of a catalyst, through a ring-opening polymerization reaction. Also, the invention pertains to a random co-poly(urethane-carbonate) bei
