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Widespread variation in salt tolerance within freshwater zooplankton species reduces the predictability of community-level salt tolerance

The salinization of freshwaters is a global threat to aquatic biodiversity. We quantified variation in chloride (Cl−) tolerance of 19 freshwater zooplankton species in four countries to answer three questions: (1) How much variation in Cl− tolerance is present among populations? (2) What factors predict intraspecific variation in Cl− tolerance? (3) Must we account for intraspecific variation to ac

Mitral regurgitation management : a systematic review of clinical practice guidelines and recommendations

Multiple guidelines exist for the diagnosis and management of mitral regurgitation (MR), the second most common valvular heart disease in high-income countries, with recommendations that do not always match. We systematically reviewed guidelines on diagnosis and management of MR, highlighting similarities and differences to guide clinical decision-making. We searched national and international gui

Perioperative interventions to reduce pancreatic fistula following pancreatoduodenectomy : meta-analysis

BACKGROUND: Data on interventions to reduce postoperative pancreatic fistula (POPF) following pancreatoduodenectomy (PD) are conflicting. The aim of this study was to assimilate data from RCTs. METHODS: MEDLINE and Embase databases were searched systematically for RCTs evaluating interventions to reduce all grades of POPF or clinically relevant (CR) POPF after PD. Meta-analysis was undertaken for

Perceptions and Experiences of Individuals With Neck Pain : A Systematic Critical Review of Qualitative Studies With Meta-Summary and Meta-Synthesis

OBJECTIVE: This study aimed at exploring the perspectives and experiences of individuals with neck pain by synthesizing all available qualitative studies. METHODS: A systematic, qualitative meta-summary and meta-synthesis was conducted following the 5-step methodology proposed by Sandelowski and Barroso. A systematic search of 9 electronic databases was conducted in May 2021. Methodological qualit

Long-Term Risk of Hospitalization for Somatic Diseases among Survivors of Childhood Acute Lymphoblastic Leukemia

Background: Survivors of childhood acute lymphoblastic leukemia (ALL) may be at increased long-term risk of hospitalization for somatic diseases. However, large population-based cohort studies with risk estimates for survivors successfully cured without experiencing a relapse or requiring hematopoietic stem cell transplantation (HSCT) are lacking. Methods: Danish and Swedish patients diagnosed wit

A Biphasic Pattern of Reproductive Hormones in Healthy Female Infants : The COPENHAGEN Minipuberty Study

CONTEXT: Minipuberty, a period of a transient activation of the hypothalamic-pituitary-gonadal (HPG) axis in both sexes, enables evaluation of gonadal function in infants suspected of hypogonadism. However, female minipuberty remains poorly elucidated. OBJECTIVE: We aimed to establish continuous reference ranges for the most commonly used reproductive hormones and to evaluate the dynamics of the H

ECG based assessment of circadian variation in AV-nodal conduction during AF—Influence of rate control drugs

The heart rate during atrial fibrillation (AF) is highly dependent on the conduction properties of the atrioventricular (AV) node. These properties can be affected using β-blockers or calcium channel blockers, mainly chosen empirically. Characterization of individual AV-nodal conduction could assist in personalized treatment selection during AF. Individual AV nodal refractory periods and conductio

Dovetail Design for Direct Cooled Rotor: Design and Manufacturing

This work investigates dovetail joints as a means to mount pre-wound coils in an electrically excited rotor for a synchronous machine for EV application. The aim is to manufacture a prototype of a direct cooled machine with hollow rectangular rotor windings which requires a rotor design where the windings can be applied on the poles separately. Two experimental tensile tests are made to validate t

Wind Energy in Denmark : A Short History [History]

This history of wind energy in Denmark describes how top-down policy support and bottom-up initiatives shaped the Danish wind power sector, ultimately facilitating the integration of wind energy in the grid. From the early days of wind power, innovative entrepreneurs tinkered with and improved upon the emergent wind power technologies, but coal and oil remained the prioritized fuels for the almost

A cognitive mess : Mixed feelings about wind farms on the Danish coast and the emotions of energy infrastructure opposition

The majority of local respondents in a large-scale survey were in favour of planned local wind farms on the Danish coast, despite these wind farm plans being the source of wider public and political contestation and opposition. Here we discuss results from the open-ended questions in the survey, specifically focusing on comments expressing how some respondents felt split in their views of these wi

The use of management controls in different cultural regions : an empirical study of Anglo-Saxon, Germanic and Nordic practices

Most cross-cultural studies on management control have compared Anglo-Saxon firms to Asian firms, leaving us with limited understanding of potential variations between developed Western societies. This study addresses differences and similarities in a wide variety of management control practices in Anglo-Saxon (Australia, English Canada), Germanic (Austria, non-Walloon Belgium, Germany) and Nordic

Comprehensive genome-wide association study of different forms of hernia identifies more than 80 associated loci

Hernias are characterized by protrusion of an organ or tissue through its surrounding cavity and often require surgical repair. In this study we identify 65,492 cases for five hernia types in the UK Biobank and perform genome-wide association study scans for these five types and two combined groups. Our results show associated variants in all scans. Inguinal hernia has the most associations and we