Sökresultat

BackgroundThe impact of a narrow true lumen (NTL) on the outcomes of fenestrated-branched endovascular repair in patients with postdissection thoracoabdominal aortic aneurysms (PD-TAAAs) is underreported.MethodsData from an international, multicenter registry were analyzed, to identify patients treated for PD-TAAAs (2015-2025) at 23 centers. All patients underwent fenestrated-branched endovascular

AimObesity is a stigmatised disease, and weight-related bullying is the most common form of victimisation. This study aimed to provide a nuanced understanding of adolescents’ experiences of such victimisation and related interventions.MethodsData were collected between April and October 2025 through semi-structured interviews and analysed using reflexive thematic analysis. Participants were Swedis

Anhedonia is a core and disabling symptom of mood disorders with limited treatment options. We evaluated the efficacy and safety of the dopamine agonist pramipexole in patients with mood disorders characterized by clinically significant anhedonia. In this single-center, randomized, double-blind, placebo-controlled trial, adults with major depressive disorder, dysthymia or bipolar depression and el

Online retail is growing rapidly, but fierce and global competition poses a challenge for retailers seeking to compete on values beyond price. Research in product and physical retail branding shows that building a relevant brand image can increase consumers’ willingness to pay a premium over competing brands with similar products. However, the academic literature lacks understanding of how brandin

Moisture‐induced deterioration is critical to building envelope durability in cold and temperate climates. To propose a new framework for selecting moisture design periods (MDPs) in Swedish building assemblies that capture sever moisture conditions more accurately, this paper evaluates different methods for producing MDPs. Using a 30‐year historical weather dataset as a benchmark, we compared simu

The present study examined the cognitive mechanisms underlying decision-making in number-line estimation in 26 preschoolers through the lens of the evidence-accumulation paradigm. Children completed a traditional Number Line Estimation Task (NLET) and the Numeracy Screener test, which assessed symbolic and nonsymbolic abilities. They also completed a novel two-alternative forced-choice version of

Seagrass meadows have been proposed as a nature-based coastal protection measure to reduce incoming wave energy. Although numerous studies have demonstrated the capability of seagrass meadows to attenuate waves, their real-world effectiveness in providing coastal protection remains uncertain. The aim of this study was to quantify the influence of a Zostera marina meadow located in a non-tidal fetc

OBJECTIVE: Chronic inflammation of the urinary bladder is associated with the bladder pain syndrome. The treatment alternatives in humans are far from satisfactory and need further attention. Well-established preclinical models have shown that pro-inflammatory cytokines contribute to the progress of the inflammatory response behind pain and hyperalgesia. Previously presented results indicate that

The issue of riba, or interest, is crucial for both Islamic and non-Islamic countries. Western economic systems use the interest rate to efficiently distribute financial resources for investment and/or consumption. In the entire economic system outside the Islamic countries, interest rates are practically a prerequisite, for the functioning of the economic system. Islamic economies, on the contrar

I rapporten undersöks hur kommuner och regioner kan stärka sin ledningsförmåga – det vill säga förmågan att samordna beslutskraft och handlingskraft – i en tid präglad av komplexa samhällsutmaningar, begränsade resurser och höga krav på legitimitet och effektivitet. Rapporten baseras på intervjuer med ledande politiker och tjänstepersoner i åtta kommuner och tre regioner. Rapportens utgångspunkt äThis report examines how municipal and regional authorities can strengthen their capacity for leadership—that is, their ability to coordinate decisiveness with effective action—in a context characterised by complex societal challenges, constrained resources, and high demands for legitimacy and efficiency. The report is based on interviews with senior elected representatives and public officials in

The conversion of a blood meal into viable offspring is a central physiological challenge for female mosquitoes. A new study has found that rectal pad cells function as a peripheral neuroendocrine hub, sensing feeding-related signals and regulating reproductive investment, linking the hindgut to reproductive decision-making.

Diel rhythms synchronized to Earth's photic cycle are near-ubiquitous among animals living in regions with distinct day-night cues. Where such cues are reduced or absent, however, activity patterns may weaken, reorganize or become decoupled from the light-dark cycle, which may allow for more flexible behavioural expression. Using a dataset of >900 free-ranging black-legged kittiwakes from colonies

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease caused by the selective loss of upper and lower motor neurons. There is a considerable variability in the disease progression of sporadic ALS, but the molecular basis for phenotypic heterogeneity remains largely unknown. ALS patients often manifest systemic metabolic abnormalities such as glucose intolerance and hyperme

Transposable elements (TEs) comprise nearly half of mammalian genomes and have shaped genome architecture, chromatin organization, and transcriptional landscapes. Thanks to recent advances in long-read sequencing and functional (epi)genomics, the focus has shifted from TE families to individual TE loci, revealing widespread, locus-specific regulatory roles. While most TEs have lost the capacity to

Wearable eye tracking in unconstrained settings is often compromised by slippage, yet the direct relationship between physical frame displacement and gaze error remains unexplored. This study addresses this gap combining eye tracking and motion capture to evaluate the slippage robustness of Pupil Labs Neon, Tobii Pro Glasses 3 and ViewPointSystems Lite eye trackers. Data were collected as twelve p