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Multiple myeloma (MM) is caused by the uncontrolled, clonal expansion of plasma cells. While there is epidemiological evidence for inherited susceptibility, the molecular basis remains incompletely understood. We report a genome-wide association study totalling 5,320 cases and 422,289 controls from four Nordic populations, and find a novel MM risk variant at SOHLH2 at 13q13.3 (risk allele frequenc
The aim of this thesis is to develop a conceptual model for understanding conditions for and outcomes of bootstrapping behaviors. Recent literature on financial bootstrapping in new firms acknowledges the necessity to consolidate and conceptualize the existing knowledge. Yet, the focus and findings of current research remain dispersed and at times contradictory, which might indicate the need for c
Muhammad Hejazi, deputy head of the Iranian Quds Force, is reported to have died of heart disease. However, a mysterious tweet hints that he might have been killed.
Debatten om covid-19 fokuserar främst på medicinska områden som smittspridning, antikroppar och vacciner. Men det finns andra aspekter som glöms bort.Våren 2020 rapporterade Interpol att stora mängder förfalskade covid-19- skyddsprodukter av olika slag var i omlopp. Nu ett år senare har den globala illegala spridningen ökat. Det gäller allt från undermåliga ansiktsmasker till sådant som utger sig
This paper addresses the influence of deteriorating structural system characteristics on the value of structural health monitoring (SHM) before its implementation. The value of SHM is calculated within a recently developed framework utilizing the Bayesian pre-posterior decision analysis modelling the structural system performance, the integrity management, the structural risks and the SHM informat
Supermassive black holes (SMBHs) are found in most galactic nuclei. A significant fraction of these nuclei also contains a nuclear stellar cluster (NSC) surrounding the SMBH. In this paper, we consider the idea that the NSC forms first, from the merger of several stellar clusters that may contain intermediate-mass black holes (IMBHs). These IMBHs can subsequently grow in the NSC and form an SMBH.
The article analyses how hunting tourism businesses in Sweden navigate in the nexus between moral and economic value spheres. Through the analytical lens of ‘moral gatekeeper’, the business operators are depicted as acting from a position where they navigate in a contested space. The analysis demonstrates how the operators balance different norms and practices of recreational hunting, wildlife man
The relationships between properties of present landscapes and species diversity within fragmented grasslands have been the subject of many studies. However the potential roles of grassland history and past landscape structure as determinants of diversity have not been widely studied. We therefore focus on these roles with an overview of patterns of variation in plant community composition in gras
We investigated allozyme variation and phenotypic variation in leaf shape in 15 populations of the shrub Hippocrepis emerus (Leguminosae) from the three isolated, regional populations in Scandinavia and analysed patterns of differentiation and the hierarchical structuring of diversity on different geographic scales There are pronounced geographic differences between the Norwegian and Swedish isola
The genetic control of variation at the Pgi‐2, Pgm‐1, Pgm‐2, and Tpi‐1 loci was investigated for the gynodioecious bladder campions, Silene uniflora and S. vulgaris. The main objective of the study was to determine whether alleles 1 and 2 at Pgi‐2, which have closely similar electrophoretic mobilities, were genuine Mendelian alleles. The results from a series of crossing experiments were consisten
