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Slutrapportering av samordning av universitetets hantering av forskningsdata

Detta är slutrapportering av rektorsuppdraget Samordning av universitetets hantering av forskningsdata, Dnr STYR 2019/295. Rapporten beskriver forskningsdataområdets disruptiva natur och dess relation till e-infrastrukturområdet, hur ett samordningsuppdrag formaliserades och med tiden formerades, vilka underprojekt som initierats och delområden som bevakats, föreslår en färdplan inför nästa steg i

Rapport för projekt Verksamhetskartläggning forskningsdata : Ett underprojekt till uppdrag Samordning av universitetets hantering av forskningsdata

Projektet har gjort en kartläggning över Lunds universitets förmågor att stötta god forskningsdatahantering med hjälp av verksamhetsarkitekturella metoder. Kartläggningen grundar sig på intervjuermed forskare, workshops med forskare, intervjuer med expertroller och stödorganisationspersonal,samt enkät till stödorganisationer. Analyser av insamlat material har resulterat i grafiska representationer

The new geographies of popular music (in a pandemic) : Guilty geographies and compressed intimacies

In this paper, I analyse developments in the relationship between popular musicians and their audiences that have intensified during the COVID-19 pandemic of 2020–21. The first, guilty geographies, concerns musicians and music venues becoming increasingly reliant on charitable audience support, appealing to fans’ ethical consciences through the crowdfunding (or fan-funding) model. The second, comp

Sex differences in off-target binding using tau positron emission tomography

Purpose: Off-target binding in the skull and meninges is observed in some subjects undergoing tau positron emission tomography (PET) and could potentially differ between men and women. In this study we elucidate sex differences in tau off-target binding using three different tau PET tracers. Methods: 541 cognitively unimpaired amyloid-β negative participants underwent tau PET using [18F]flortaucip

Reduction in the amount of sulfur in waste oil using reactive molecular distillation

Petroleum, contains proportions of contaminants such as sulfur, nitrogen, oxygen, and metals, such as nickel, iron, copper, sodium, and vanadium. Particularly, contaminants containing sulfur cause problems during handling, transportation, and the use of the their derivatives. This work had the goal of cracking the heavy crude oil molecules by reacting these molecules with tetralin and simultaneous

Novel approaches in cardiac imaging for non-invasive assessment of left heart myocardial fibrosis

In the past, the identification of myocardial fibrosis was only possible through invasive histologic assessment. Although endomyocardial biopsy remains the gold standard, recent advances in cardiac imaging techniques have enabled non-invasive tissue characterization of the myocardium, which has also provided valuable insights into specific disease processes. The diagnostic accuracy, incremental yi

Different feeding regimens were not associated with variation in body composition in preterm infants

Aim: The aim was to determine body composition and growth in preterm infants based on two different feeding regimens and to assess how standard and individual fortification (IF) affect energy and protein intake. Body composition was assessed at full term and at four months corrected age. Methods: Sixty preterm infants born before gestational week 32 were randomized either to IF of mother’s breast

Transition policies for climatically sustainable aviation

Emissions from aviation are expected to grow. With evidence that the International Civil Aviation Organization’s Carbon Offsetting and Reduction Scheme for International Aviation is an inadequate mitigation mechanism, there is interest in upscaling the sector’s climate-related policies. This paper reviews potential aviation emissions mitigation policies against the background of emerging complexit

Selection of the optimal candidate to mitraclip for secondary mitral regurgitation : Beyond mitral valve morphology

Secondary mitral regurgitation (MR) occurs despite structurally normal valve apparatus due to an underlying disease of the myocardium leading to disruption of the balance between tethering and closing forces with ensuing failure of leaflet coaptation. In patients with heart failure (HF) and left ventricular dysfunction, secondary MR is independently associated with poor outcome, yet prognostic ben

Glucocorticoid induced TNF receptor family-related protein (GITR) – A novel driver of atherosclerosis

Atherosclerosis is a lipid-driven, chronic inflammatory disease. In spite of efficient lipid lowering treatments, such as statins and PCSK9 inhibitors, patients, especially those with elevated inflammatory biomarkers, still have a significant residual cardiovascular disease risk. Novel drugs targeting inflammatory mediators are needed to further reduce this residual risk. Agonistic immune checkpoi

Mortality after Ischemic Stroke in Patients with Alzheimer's Disease Dementia and Other Dementia Disorders

Background: Stroke and dementia are interrelated diseases and risk for both increases with age. Even though stroke incidence and age-standardized death rates have decreased due to prevention of stroke risk factors, increased utilization of reperfusion therapies, and other changes in healthcare, the absolute numbers are increasing due to population growth and aging. Objective: To analyze predictors

A review of romiplostim mechanism of action and clinical applicability

Thrombocytopenia results from a variety of conditions, including radiation, chemotherapy, autoimmune disease, bone marrow disorders, pathologic conditions associated with surgical procedures, hematopoietic stem cell transplant (HSCT), and hematologic disorders associated with severe aplastic anemia. Immune thrombocytopenia (ITP) is caused by immune reactions that accelerate destruction and reduce

The B-Natural study—The outcome of immune tolerance induction therapy in patients with severe haemophilia B

Introduction: Inhibitors develop less frequently in haemophilia B (HB) than haemophilia A (HA). However, when present, the success of tolerization by immune tolerance induction (ITI) therapy is lower and the risk of complications higher. Aim: To evaluate the use and outcome of ITI in patients with HB and inhibitors. Methods: Subjects include singletons or siblings with a current/history of inhibit

Predicting pathological axillary lymph node status with ultrasound following neoadjuvant therapy for breast cancer

Purpose: High-performing imaging and predictive markers are warranted to minimize surgical overtreatment of the axilla in breast cancer (BC) patients receiving neoadjuvant chemotherapy (NACT). Here we have investigated whether axillary ultrasound (AUS) could identify axillary lymph node (ALN) metastasis (ALNM) pre-NACT and post-NACT for BC. The association of tumor, AUS features and mammographic d

COVID-19 weakens both sides in the battle between coal and renewables

By disrupting investment, supply chains and technology diffusion, COVID-19 may harm renewables more than coal, but still weaken coal lock-in in developing countries. To enable new low-carbon energy choices, international flows of low-carbon technology and policy expertise must quickly re-emerge.

Muconic Acid Production Using Engineered Pseudomonas putida KT2440 and a Guaiacol-Rich Fraction Derived from Kraft Lignin

Industrial lignin such as kraft lignin is an abundant feedstock for renewable chemicals and materials. In this study, a process was developed for depolymerization of kraft lignin followed by an upgrading separation step and further bioconversion of the obtained monoaromatic compounds to muconic acid. First, industrial kraft lignin, Indulin AT, was processed into a guaiacol-rich stream using base-c

Innovation in the long run: Perspectives on technological transitions in Sweden 1908-2016

There are fundamental unresolved questions about the nature of the long-run interplay between innovation and economic development processes. This study examines technological transitions in Sweden, 1908-2016, using a new literature-based innovation output indicator for the engineering industry, allowing a mixed-methods approach. The results suggest that waves of innovation have taken place during

Experimental wildfire induced mobility of radiocesium in a boreal forest environment

Wildfires are expected to increase with warmer climate, which can contribute to the mobility and the resuspension of long-lived and potentially hazardous radionuclides. The release of 137Cs during combustion of dried litter, forest floor organic soil, and peat was investigated in a small-scale experimental set-up. Combustion conditions were varied to simulate different wildfire scenarios, and the