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Bringing SMS in Aviation to Life by Human Integration: Building on the Basis of ICAO SMS and Transitioning away from a Static Regulatory Approach

The ICAO approach to risk management is essentially a technical model based on an engineering process viewpoint and is more applicable in concept to stable systems, such as chemical and nuclear industries. If airlines are to manage risk in a proactive manner they need to apply risk detection tools that provide real time and continuous systems oversight. This paper describes briefly the systems ap

Smuggling of asylum-seekers and criminal justice

The objective of this paper is to demonstrate the legal implications for asylum-seekers flowing from their resort to falsified documents as a method of gaining access to the territory of asylum countries. Article 31(1) of the Refugee Convention is supposed to act as a shield against punishment for illegal entry. However, the paper identifies four issues relating to the application of Article 31 wh

GALIELLALACTONE ANALOGUES – SYNTHESIS AND PROPERTIES

Popular Abstract in Swedish Efter hand som människans livslängd ökar, ökar också frekvensen av och dödligheten i cancer. För att cancer ska kunna överleva och inte selekteras ut och attackeras av kroppens immunförsvar måste den anpassa sig till och styra sin omgivning. Ett sätt att motarbeta cancern är att angripa proteiner som är nödvändiga för cancerns överlevnad. Naturprodukten galiellalakton hCancer cells use normal cell signalling pathways in a proliferative fashion in order to prolong their own survival. Inhibition of one of the major signal proteins, STAT3 (Signal Transducer and Activator of Transcription 3) has previously been shown to induce apoptosis. Galiellalactone, a fungal metabolite, inhibits STAT3, thus presenting a potential lead for cancer treatment. The inhibition is bel