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Understanding the evolution of evolvability—the evolutionary potential of populations—is key to predicting adaptation to novel environments. Despite growing evidence that evolvability structures adaptation, it remains unclear how adaptation to novel environments in turn influences evolvability. Here we address the interplay between adaptation and evolvability in the peacock fly Tephritis conura, w
In Mantle Cell Lymphoma (MCL), the role of macrophages within the tumour microenvironment (TME) has recently gained attention due to their impact on prognosis and response to therapy. Despite their low absolute number in MCL tumour tissue, recent findings reveal an association between the levels of macrophages and prognosis, consistent with trends observed in other lymphoma subtypes. M2-like macro
This open access book tells stories of conviviality, solidarity, and everyday management of conflicts and tensions, by building on original, long-term ethnographic research (fourteen months in 2009-2010, followed by fieldwork trips until now) on Burgaz, an island home to more than twenty ethnic and religious groups from different socio-economic backgrounds. The island provides an excellent case st
PURPOSE: The gold standard for skin cancer diagnosis is surgical excisional biopsy and histopathological examination. Several non-invasive diagnostic techniques exist, although they have not yet translated into clinical use. This is a proof-of-concept study to assess the possibility of imaging an angiosarcoma in the periocular area.METHODS: We use laser speckle, hyperspectral, and photoacoustic im
Serum electrophoresis (SPEP) is a method used to analyze the distribution of the most important proteins in the blood. The major clinical question is the presence of monoclonal fraction(s) of antibodies (M-protein/paraprotein), which is essential for the diagnosis and follow-up of hematological diseases, such as multiple myeloma. Recent studies have shown that machine learning can be used to asses
A foreseeable challenge with a substantial increase in railway mode share will be how to uphold punctuality. Higher volumes of train traffic will result in timetables that are more sensitive to disruptions; whose severity and frequency is also expected to increase in light of greater asset utilization and climate change. This calls for a definitive understanding of the relationship between inciden
Most companies and organizations are primarily interested in universities' educational activities and to a lesser extent in universities' research activities. Against this background, it is strange that the research on collaboration between universities and the surrounding society is primarily directed towards research collaboration between universities and companies/organizations and to a lesser
The articles in this volume largely come from the international conference “Childhood at War and Genocide: Children’s Experiences of Conflict in the 20th Century—Agency, Survival, Memory and Representation” that took place between October 17 and 19, 2022 at the Centre for Holocaust Studies at the Leibniz Institute for Contemporary History (IfZ) in Munich, with the cooperation of Fritz Bauer Instit
In this paper, we estimate the vulnerability of railway infrastructure, switches, signals, tracks, and catenaries to different weather conditions, temperature, precipitation, snow depth, and wind speed across the entire Swedish railway network between 2006-2020. Using a method to quantify the fault rate we establish thresholds that can be useful for identifying areas of concern for operations. Res
Objective: Acceptance and commitment therapy (ACT) is a transdiagnostic, behavioral treatment focusing on common processes behind different diagnoses. Internet-based treatment programs can improve access to treatment and easily be integrated into the individual’s life. Method: This single-arm, pre-post-follow-up pilot study examined the acceptability, safety, and effectiveness of internet-based AC
A 12-bit time-interleaved (TI) analog-to-digital converter (ADC) with pipelined successive-approximation (SAR) channels is presented in this paper. The ADC consists of four TI channels, each incorporating a two-stage pipelined asynchronous SAR ADC. To facilitate clock distribution, a common bootstrapped sampler in front of the four channels is employed. The reset switch in the capacitive digital-t
The Journal of Comparative Physiology A is the premier peer-reviewed scientific journal in comparative physiology, in particular sensory physiology, neurophysiology, and neuroethology. Founded in 1924 by Karl von Frisch and Alfred Kühn, it celebrates its 100th anniversary in 2024. During these 100 years, many of the landmark achievements in these disciplines were published in this journal. To comm
Background & Aims: Inflammatory bowel disease (IBD) is linked to reduced female fertility, but it is unclear how fertility rates vary by histologic disease activity. Methods: Nationwide IBD cohort of Swedish women aged 15 to 44 years. We examined fertility rates during periods with vs without histologic inflammation (n = 21,046; follow-up, 1990–2016) and during periods with vs without clinical
We present a micro-Raman study of InP/InGaP tandem junction photovoltaic nanowires. These nanowires render possible InGaP compositions that cannot be made in thin films due to strain. The micro-Raman spectra acquired along the nanowires reveal the existence of compositional changes in the InGaP alloy associated with the doping sequence. The heavily Zn-doped InxGa1-xP (x is the In molar fraction) s
The electronic structure and geometrical organization of aqueous Cu2+ have been investigated by using X-ray photoelectron spectroscopy (XPS) at the Cu L-edge combined with state-of-the-art ab initio molecular dynamics and a quantum molecular approach designed to simulate the Cu 2p X-ray photoelectron spectrum. The calculations offer a comprehensive insight into the origin of the main peak and sate
