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Nuclear factor Y is a pervasive regulator of neuronal gene expression

Nervous system function relies on the establishment of complex gene expression programs that provide neuron-type-specific and core pan-neuronal features. These complementary regulatory paradigms are controlled by terminal selector and parallel-acting transcription factors (TFs), respectively. Here, we identify the nuclear factor Y (NF-Y) TF as a pervasive direct and indirect regulator of both neur

Sustainable One-Pot Synthesis of 5-(Hydroxymethyl)furfural from C6-Sugars by Enhanced H+ Exchange Heterogeneous Catalysis

This study focuses on the characterization of NaCl-induced enhancement of H+ exchange catalysis and preparation of the renewable C6 platform chemical, 5-(hydroxymethyl)furfural (5-HMF), through dehydration of fructose and glucose, C6-sugars, utilizing a heterogeneous catalyst. The effect of a catalytic amount of NaCl was explored to enhance the H+ exchange of cation exchangers, characterized on th

‘Ageing with an alcohol problem is not what I envision’: reclaiming agency in shaping personal ageing trajectory and recovery from alcohol problems

BackgroundEliciting and understanding older persons’ descriptions of their resources for healthy ageing and the interaction of these resources with alcohol use and alcohol problems can facilitate health promotion. It can also inform clinicians when identifying areas of recovery capital that present risks and strength for older people seeking alcohol treatment. The objective of this study was to il

Wassermann (e. 53) for tape

TITLE: WassermannCAT# (YEAR COMPOSED): #53 (1999)INSTRUMENTATION: for electronic playbackDURATION (APPROX): 10’59PUBLICATION: published recording on 'ELECTRONIC VOICES', Galerie SPHNHenry Miller in Big Sur and the Oranges of Hieronymous Bosch provides a description of transformation that was similar to the spirit of Wassermann “Every creature, every object, every place has its own ambience which i

Flintmining at Södra Sallerups (Sweden)

The area in Södra Sallerup is, as far as we know, the only large-scale flint mining area in Sweden. Radiocarbon dates indicate that the flint was mined mainly during the Early Neolithic. It is clear, however, that the flint that was scattered throughout the area by the mining activity was used during later periods, even as late as the Viking and Medieval Periods.The large-scale mining during the E

Spel i undervisning och forskning : Att lära ut till och samtidigt lära av studenter

Ett nytt moment har införts på de två nya civilingenjörsprogrammen i brandteknik och riskhantering vid LTH: ett spelmoment där studenterna ställs inför ett simulerat riskhanteringsscenario där de med begränsade resurser och osäkra framtidsutsikter är satta att hantera översvämningsrisker i en humanitär kontext. De får öva på att fatta beslut för att försöka undvika kris och hushålla med värdefulla

Har du undermedvetna fördomar? : Ett interaktivt föredrag om jämställdhet på LTH

Undermedvetna könsstereotyper och fördomar påverkar jämställdheten i akademin, och även de som tror att de har en jämställd syn kan vara påverkade av dessa implicita bias. Kvinnor inom naturvetenskapliga ämnen både bedöms hårdare inom undervisning, bedömning, granskning och rekrytering och undervärderar sina egna akademiska förmågor vilket leder till en långsammare karriärsutveckling och i förläng

Impact of Climate Change on Extreme Events: Insights from Asia and Scandinavia

As climate has warmed significantly over past decades, numerous studies have confirmed a pattern of more frequent and more intense hydro-climate events across the globe, such as floods, heatwaves, and droughts. Analyzing the variability of climate events with reliable historical data records is one of the most direct approaches for understanding its patterns of change. The development of climate m

Valorization of biomass related substrates into value added chemicals : Hydrogen transfer catalysis

In the current global scenario, it is evident that global warming and climate change are primarily driven by emissions stemming from the utilization of fossil fuels. Yet, if we look around, most of what we see is made from or linked to fossil fuels and it clearly shows our over-dependency on fossil fuels and hence there is a significant need to develop alternate sources of energy and raw materials

Towards Explaining Satellite Based Poverty Predictions with Convolutional Neural Networks

Deep convolutional neural networks (CNNs) have been shown to predict poverty and development indicators from satellite images with surprising accuracy. This paper presents a first attempt at analyzing the CNNs responses in detail and explaining the basis for the predictions. The CNN model, while trained on relatively low resolution day- and night-time satellite images, is able to outperform human

Evidence for an L3 phase in ternary deep eutectics : composition-induced L3-to-Lα transition of AOT

Pure and hydrated deep eutectic solvents (DES) are proposed to form self-assembled nanostructures within the fluid bulk, similar to the bicontinuous L3 phase common for ionic liquids (ILs). Labelled choline chloride : urea : water DES were measured using small-angle neutron scattering (SANS), showing no long-range nanostructure. However, solutions of the surfactant AOT in this DES yielded scatteri

Nanostructure in Amphiphile-Based Deep Eutectic Solvents

Deep eutectic solvents (DESs) are an emerging class of modern, often “green” solvents with unique properties. Recently, a deep eutectic system based on amphiphilic surfactant N-alkyl-N,N-dimethyl-3-ammonio-1-propanesulfonate (C12 & C14 sulfobetaine) and (1S)-(+)-10-camphor-sulfonic acid in the molar ratio 1:1.5 has been reported. Nanostructuring can be expected in this DES due to the nature of

Use of non-surgical treatments on the journey to knee replacement in patients with knee osteoarthritis : A 10-year population-based case-control study

Aim To investigate temporal trends in primary care visits, physiotherapy visits, dispensed non-steroidal anti-inflammatory drugs (NSAIDs) and opioids in knee osteoarthritis (OA) patients who have and have not undergone knee replacement. Methods We analysed 5665 OA patients from the Skåne Healthcare Register, Sweden, who underwent knee replacement between 2015 and 2019. Controls were OA patients wi