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High-dimensional cortical signals reveal rich bimodal and working memory-like representations among S1 neuron populations

Complexity is important for flexibility of natural behavior and for the remarkably efficient learning of the brain. Here we assessed the signal complexity among neuron populations in somatosensory cortex (S1). To maximize our chances of capturing population-level signal complexity, we used highly repeatable resolvable visual, tactile, and visuo-tactile inputs and neuronal unit activity recorded at

Rationale and design of the BeyeOMARKER study : prospective evaluation of blood- and eye-based biomarkers for early detection of Alzheimer’s disease pathology in the eye clinic

Background: Alzheimer’s disease (AD) is a common, complex and multifactorial disease that may require screening across multiple routes of referral to enable early detection and subsequent future implementation of tailored interventions. Blood- and eye-based biomarkers show promise as low-cost, scalable and patient-friendly tools for early AD detection given their ability to provide information on

Spatial resolution and optical sensitivity in the compound eyes of two common European wasps, Vespula germanica and Vespula vulgaris

Vespula germanica and Vespula vulgaris are two common European wasps that have ecological and economic importance as a result of their artificial introduction into many different countries and environments. Their success has undoubtedly been aided by their capacity for visually guided hunting, foraging, learning and using visual cues in the context of homing and navigation. However, the visual sys

Isolated attosecond pulse generation in a semi-infinite gas cell driven by time-gated phase matching

Isolated attosecond pulse (IAP) generation usually involves the use of short-medium gas cells operated at high pressures. In contrast, long-medium schemes at low pressures are commonly perceived as inherently unsuitable for IAP generation due to the nonlinear phenomena that challenge favourable phase-matching conditions. Here we provide clear experimental evidence on the generation of isolated ext

Associations between physical activity and ankle-brachial index : the Swedish CArdioPulmonary bioImage Study (SCAPIS)

Background: The ankle–brachial index (ABI) is the ratio of the ankle and brachial systolic blood pressures. In the clinical setting, low ABI (< 0.9) is an indicator of peripheral atherosclerosis, while high ABI (> 1.4) is a sign of arterial stiffness and calcification. The purpose of the current study was to investigate the association between ABI and physical activity levels, measured by accelero

Does Peer Socialization Within Cohorts Foster Political Attitudes? A Longitudinal Study of Elite Business Students

The association between higher education and political attitudes is well-recognized, and research suggests that socialization amongst peers is one of the most probable mechanisms explaining a possible attitudinal change. However, identifying a socialization effect is difficult due to self-selection mechanisms and limitations in data availability. This article empirically investigates the underlyin

ChatGeoAI: Enabling Geospatial Analysis for Public through Natural Language, with Large Language Models

Large Language Models (LLMs) such as GPT, BART, and Gemini stand at the forefront of Generative Artificial Intelligence, showcasing remarkable prowess in natural language comprehension and task execution. This paper proposes a novel framework developed on the foundation of Llama 2, aiming to bridge the gap between natural language queries and executable code for geospatial analyses within the PyQG

Topological superconductivity in Fibonacci quasicrystals

We investigate the properties of a Fibonacci quasicrystal (QC) arrangement of a one-dimensional topological superconductor, such as a magnetic atom chain deposited on a superconducting surface. We uncover a general mutually exclusive competition between the QC properties and the topological superconducting phase with Majorana bound states (MBS): there are no MBS inside the QC gaps and the MBS neve

Inpatient Suicides in Swedish Psychiatric Settings - A Retrospective Exploratory Study from a Nursing Perspective

In Sweden, approximately 1,200 individuals die by suicide annually. Inpatient suicide is considered rare, but death by suicide still occurs when admitted to a psychiatric hospital. This study was part of a national retrospective project covering data from all patients' medical records for the 2 years before death by suicide in 2015. In this study, 41 patients who died by suicide while being admitt

A study protocol of the effectiveness of the Attempted Suicide Short Intervention Program (ASSIP) for recent suicide attempters : a randomized controlled trial

BACKGROUND: Given the limited research focusing on psychotherapeutic interventions for suicide attempters, it is noteworthy that the Attempted Suicide Short Intervention Program (ASSIP) has demonstrated promising results in previous studies. In this investigation, we aim to evaluate the effectiveness of ASSIP across diverse healthcare settings, outlining the study design and planned evaluation.MET

Excess mortality and suicide risk in treatment-seeking individuals with schizotypal disorder : A population-based study using Swedish national registers

This study investigates the excess mortality, both all-cause and due to suicide, among individuals with schizotypal disorder (SD) compared to the general population. Using individual-level data from the Swedish National Patient Register and the Cause of Death Register, we analyzed mortality in 998 patients diagnosed with SD from 2006 to 2017. Our primary outcomes were all-cause mortality and suici

Marital Status and Serum Level of Testosterone: In Relation to Serum Level of Cortisol

Purpose: To explore the association between marital status and testosterone, and cortisol serum levels in 119 healthy men aged 45 to 60 years representing the general population. Material and Methods: Data on men’s age, waist circumference, body mass index, smoking, alcohol consumption, and marital status were collected. Serum levels of LH, testosterone, and cortisol were also measured. Two groups

Association between Serum Cortisol Level and Erectile Function in Healthy Men from the General Population

Purpose: The aim of the study is to investigate the association between serum levels of cortisol and erectile function in healthy men aged 45-60 years.Material and methods: The serum level of cortisol was measured. The international index of erectile function-5 items (IIEF-5) was used to assess the erectile function.Data were gathered on the age of participants, Body Mass Index (BMI), waist circum