Objective: Monoclonal gammopathy of undetermined significance (MGUS) is the asymptomatic precursor of multiple myeloma (MM). Lytic bone lesions and fractures are hallmarks of MM and although there are no lytic lesions in MGUS, it has also been associated with fractures. The causes of fractures in MGUS are currently unclear but potential causes include inherent MGUS bone disease, undiagnosed MM, an

Pluvial flood damage to residential buildings causes a significant part of direct tangible flood losses. In this study, we investigate the non-hazard variables and sewer system types in relation to damage costs in the city of Malmö, Sweden. A comprehensive data set of around 1000 records of direct damage to residential buildings from a cloudburst event on 31 August 2014 in Malmö, Sweden has been a

Swedish has been generally assumed not to have any well-defined question intonation. However, with respect to Southern Swedish, Lindblad & Gårding (1973) present data showing final rises in polar (Y/N) questions. Gårding (1979) also assumes a broader and higher F0 range in Y/N questions than in statements, particularly on the final focussed word. The present study investigates the extent to wh

This new edition includes a greater focus on applicable ISO standards in facility management as well as maintaining an international perspective throughout. It covers: the fundamentals of facility management, including key roles, responsibilities and accountabilities and the core competencies of facility management; an exploration of facility planning, facility management strategy, outsourcing, pr

As a growing number of diplomatic practices take new digital forms, research on digital diplomacy is rapidly expanding. Many of the changes linked to digitalization transform or challenge traditional ways of doing diplomacy. Analyses of new forms of “digital diplomacy” are therefore valuable for the advancement of practice approaches in international relations theory. That said, digital diplomacy

Postural orthostatic tachycardia syndrome (POTS) is a chronic and often disabling disorder characterized by orthostatic intolerance with excessive heart rate increase without hypotension during upright posture. Patients often experience a constellation of other typical symptoms including fatigue, exercise intolerance and gastrointestinal distress. A typical patient with POTS is a female of child-b

This chapter reports preliminary findings from a study of epistemic consequences of misinformation in social networks. It uses the methodology of computer simulation, constructing computer models of Bayesian learning in networks that include untrustworthy sources. Censorship and de-platforming take time and money, and they violate social and democratic norms of inclusiveness and free speech. Enqui

BACKGROUND: Surgical safety during posterior sagittal anorectal plasty (PSARP) for anorectal malformations (ARM) depends on accurate pre-operative fistula localization. This study aimed to evaluate accuracy of pre-operative fistula diagnostics.METHODS: Ethical approval was obtained. Diagnostic accuracy of pre-PSARP symptoms (stool in urine, urine in passive ostomy, urinary tract infection) and exa

Background: Accumulation of alpha-synuclein (α-syn) is a main pathological hallmark of Parkinson’s and related diseases, which are collectively known as synucleinopathies. Growing evidence has supported that the same protein can induce remarkably distinct pathological progresses and disease phenotypes, suggesting the existence of strain difference among α-syn fibrils. Previous studies have shown t

Is audit capable of evolving into something that is more consistently valued and socially purposeful? We address this fundamental question, utilizing Sennett’s (2008). The Craftsman. New Haven: Yale University Press) notion of ‘dynamic repair’ to present four key ways of thinking differently about the statutory financial audit and its core conceptual foundations. First, we highlight the capacity f

This article investigates the microstructure evolution and corrosion response of surface mechanical attrition treated (SMAT) AZ91D magnesium alloy. In-depth transmission electron microscopy and combined isothermal calorimetry and pressure measurement technique, a novel and powerful tool for in situ monitoring of the magnesium corrosion process, are explored in the present study. A gradient structu

This article argues that while HTS’s transformation and split from al-Qaeda is real, al-Jolani must be pressured to share power over Idlib and loosen his group’s authoritarian grip, which is causing grievances that in the long term will push locals into the hands of radical groups like ISIS and al-Qaeda.

This report assesses the phenomenon of in-work poverty in Sweden inrelation to the four specific VUP groups identified within the Working, Yet Poor project. It is shown that the main drivers of in-work poverty in Sweden are not related to the wage setting system as dealt with through collective bargaining as such. Rather, in-work poverty is more closely associated with work-intensity affecting wor