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Recent studies provide insights about local agency in regional development. While acknowledging non-local actors and drivers, these studies have not systematically discussed the link between extra-regional relations and local agency. This paper first discusses three key arguments in the literature on extra-regional relations covering context-specific dependencies, strategic coupling and open innov

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The present invention relates to a method of removing an endotoxin from solution containing basic proteins. More specifically, the method of the present invention comprises the steps of adding the surfactant to solution containing the basic protein obtained from the recombinant microorganism and mixing the resultant, of loading the resultant solution on the cation exchange column, washing the cati

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The practices of doctoral education are intricately entangled with technologies. This methodological paper examines the practical concerns involved in doing the analytic work in a networked learning setting with Actor-Network theory (ANT). It is a story about engaging with ANT as a companion in an ethnographic research project on teaching practices in Sweden during the Covid-19 pandemic. The empir

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The paper explores what the methodological considerations are for a study of educational practice and networked learning in technologically dense classrooms. The approach of the discussed study is informed by Actor-Network Theory (ANT) (Latour, 2005) and the paper outlines the methodological consequences for adopting principles associated with ANT and post-humanist critiques of representational ep

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Controlling the surface morphology and chemical interaction is necessary for the development of advanced quantummaterials, particularly in low-dimensional systems. As the research increasingly focuses on miniature and nanoscaletechnologies, a fundamental understanding of localized or interface states becomes essential for successful integrationinto functional devices. This thesis investigates atom

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Chemical exchange saturation transfer MRI is a promising magnetization transfer (MT) imaging technique that utilizes, by radiofrequency irradiation, selective saturation of exchangeable protons in solutes. This enables the indirect detection of the solutes through the water signal after saturation transfer by chemical exchange, cross-relaxation, or the combination of the two. Typically, the water-

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INTRODUCTION: Epidemiological studies focusing on the association of exposure to perfluoroalkyl substances (PFAS) with cardiovascular disease (CVD) morbidity and mortality are limited, with inconsistent findings.OBJECTIVES: This register-based study aimed to investigate the associations between exposure to PFAS and the risk of CVD morbidity and mortality in a Swedish population exposed to PFAS, do

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This study investigated the associations between solar and geomagnetic activity and circulating biomarkers of systemic inflammation and endothelial activation in the Normative Aging Study (NAS) cohort. Mixed effects models with moving day averages from day 0 to day 28 were used to study the associations between solar activity (sunspot number (SSN), interplanetary magnetic field (IMF)), geomagnetic

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Estrogen influences T cell development and enhances infection resistance in females, but its immunological effects during gender-affirming hormone therapy (GAHT) remain poorly understood. Here, we characterize immune adaptations in male rhesus macaques (RMs) treated with 17β-estradiol (E2) or placebo over 7 months. E2 therapy suppressed endogenous testosterone production, induced female physical t

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Immune function varies widely across humans. Biological sex is a key factor underlying human immune variability, with men presenting with more severe infections and increased cancer rates, while women exhibit higher vaccine responses and prevalence of autoimmunity. Intrinsic biological sex differences arise from varying contributions of chromosomal sex, and sex hormone sensing and downstream signa

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OBJECTIVE: To externally validate the Paediatric Emergency Care Applied Research Network (PECARN) rule for identifying febrile infants aged <60 days at low risk of serious bacterial infections (SBIs) and assess the utility of the rule with C reactive protein (CRP) instead of procalcitonin (PCT).METHODS: Secondary analysis of data from the Management and Outcomes of Fever in Children in Europe (MOF

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This study focuses on the introduction of new nuclear, particularly Small Modular Reactors (SMRs) in Sweden. The Swedish Government has decided on a revival for nuclear energy where SMRs are an important contribution to reach the goal of a total output of at least 2 500 MW by 2035. In this stage when much is unclear about the re-introduction and SMRs are under development media is an important age

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Bladder cancer is the ninth most common type of cancer globally, and the projected number of deaths is estimated to almost double by the year 2040. Immunotherapy with checkpoint inhibitors has revolutionized treatment of bladder cancer and can achieve durable responses; however, only a minority of patients respond. By identifying additional targets and treatment combinations, more patients could b

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While leadership is generally understood as an agentic process, there are divergent positions in the literature regarding the extent to which agency is to be understood as centralized in individuals and individual actions or distributed among actors and located in the collaborative process itself. In this study, we align with post-heroic studies of the realization of moments of leadership through

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Data and code are essential for ensuring the credibility of scientific results and facilitating reproducibility, areas in which journal sharing policies play a crucial role. However, in ecology and evolution, we still do not know how widespread data- and code-sharing policies are, how accessible they are, and whether journals support data and code peer review. Here, we first assessed the clarity,