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Conceptualizing Flexible Organizational Structures in Social Movements of Neglected Geographies: A Case Study of the Shame Movement’s Transformation in Georgia

The success of social movements is highly dependent on their sustainability, as in their efforts to produce meaningful change, they inevitably encounter oppressive dominant forces. With the advent of the social media era, scholarly research on collective action has acquired an additional dimension, bringing the role of their communicative constitution to the forefront of discussions. However, a de

Oral histories of domestic heating transitions in England and Sweden : lessons on how heating transitions play out across place and time

Over the last seventy years, most European countries have undergone one or more transitions in home heating provision. Moving first away from burning solid fuels and towards communal or individual central heating systems and now towards low carbon electric heating systems. Heating transitions are awash with personal, social and cultural complexity but tend to be simplified into grand narratives th

Using provocative PR and promotional communication to leverage a vegan activist brand: An exploratory study of Mr. Charlie’s communicative strategies

An increasingly competitive market, as well as transforming consumer expectations, have considerably altered the socio-economic landscape in which contemporary profit-making organizations operate. As a result, it is more difficult than ever to establish a successful and distinct brand, whilst adhering to fast-changing customer demands – especially when consumers bank on brands to fulfil a higher p

Moving beyond Mediatized Activism for Social Justice: Creating Visual Safe/Brave Spaces for Activists

The large-scale mass mobilizations and colossal demonstrations of the last decade have shown that digital and social media platforms, globally, now play significant roles in early formation and further facilitation of activist movements, interested in progressive causes and societal changes. However, the repercussions of the very same events have also clearly shown the shortcomings of mediatized a

The Trolley Problem and Isaac Asimov's First Law of Robotics

How to make robots safe for humans is intensely debated, within academia as well as in industry, media and on the political arena. Hardly any discussion of the subject fails to mention Isaac Asimov’s three laws of Robotics. We find it curious that a set of fictional laws can have such a strong impact on discussions about a real-world problem and we think this needs to be looked into.The probably mHow to make robots safe for humans is intensely debated, within academia as well as in industry, media and on the political arena. Hardly any discussion of the subject fails to mention Isaac Asimov’s three laws of Robotics. Asimov’s laws and the Trolley Problem are usually discussed separately but there is a connection in that the Trolley Problem poses a seemingly unsolvable problem for Asimov’s F

The Lessons of the Gezi Park Protests in Turkey

The mass mobilization and the collective political engagement of the Gezi Park protests of 2013 came as a surprise for many in Turkey. What was new about these large-scale demonstrations was not only the sheer number of people taking place in them (more than 3.5 million), but rather the expansive range of the protesters.This presentation looks into the Gezi events through a research question of Ho

A data-driven biocomputing pipeline with meta-analysis on high throughput transcriptomics to identify genome-wide miRNA markers associated with type 2 diabetes

BACKGROUND: MicroRNAs (miRNAs) are sought-after biomarkers of complex, polygenic diseases such as type 2 diabetes (T2D). Data-driven biocomputing provides robust and novel avenues for synthesizing evidence from individual miRNA seq studies.OBJECTIVE: To identify miRNA markers associated with T2D, via a data-driven, biocomputing approach on high throughput transcriptomics.MATERIALS AND METHODS: The

Highly perturbed genes and hub genes associated with type 2 diabetes in different tissues of adult humans : a bioinformatics analytic workflow

Type 2 diabetes (T2D) has a complex etiology which is not yet fully elucidated. The identification of gene perturbations and hub genes of T2D may deepen our understanding of its genetic basis. We aimed to identify highly perturbed genes and hub genes associated with T2D via an extensive bioinformatics analytic workflow consisting of five steps: systematic review of Gene Expression Omnibus and asso

Do Probiotics Cause a Shift in the Microbiota of Dental Implants-A Systematic Review and Meta-Analysis

OBJECTIVE: The primary aim of this current systematic review and meta-analysis was to evaluate the potential microbiological effect of probiotics on the implant microbiota. The secondary aim was to evaluate if probiotics have any effect as an adjunct to non-surgical peri-implant treatment in reducing peri-implant mucositis and peri-implantitis clinical parameters-bleeding on probing, modified Ging

Nutritional markers of undiagnosed type 2 diabetes in adults : Findings of a machine learning analysis with external validation and benchmarking

OBJECTIVES: Using a nationally-representative, cross-sectional cohort, we examined nutritional markers of undiagnosed type 2 diabetes in adults via machine learning.METHODS: A total of 16429 men and non-pregnant women ≥ 20 years of age were analysed from five consecutive cycles of the National Health and Nutrition Examination Survey. Cohorts from years 2013-2016 (n = 6673) was used for external va

Clinical notes as prognostic markers of mortality associated with diabetes mellitus following critical care : A retrospective cohort analysis using machine learning and unstructured big data

BACKGROUND: Clinical notes are ubiquitous resources offering potential value in optimizing critical care via data mining technologies.OBJECTIVE: To determine the predictive value of clinical notes as prognostic markers of 1-year all-cause mortality among people with diabetes following critical care.MATERIALS AND METHODS: Mortality of diabetes patients were predicted using three cohorts of clinical

Twenty-year trajectories of morbidity in individuals with and without osteoarthritis

OBJECTIVES: To identify multimorbidity trajectories over 20 years among incident osteoarthritis (OA) individuals and OA-free matched references.METHODS: Cohort study using prospectively collected healthcare data from the Skåne region, Sweden (~1.4 million residents). We extracted diagnoses for OA and 67 common chronic conditions. We included individuals aged 40+ years on 31 December 2007, with inc

Label-free quantitative proteomics reveals differentially regulated proteins in experimental gingivitis

We investigated the sequential protein expression in gingival crevicular fluid samples during the induction (I) and resolution (R) of experimental gingivitis. Periodontally and systemically healthy volunteers (n = 20) participated in a three-week experimental gingivitis protocol, followed by debridement and two weeks of regular plaque control. Gingival crevicular fluid (GCF) samples were collected

Antimicrobial Peptides : Roles in Periodontal Health and Disease

Why do cockroaches and rats survive in sewers and other extremely challenging conditions? The answer is that through evolution they have been equipped with antimicrobial peptides (AMPs) that protect them from microbiological insult. In the case of cockroaches and rats, the AMPs are very potent, allowing for these challenging environments [1–3]. AMPs are the most ancient and primitive arm of the hu

Three-Dimensional Large-Eddy Simulation of Non-Premixed H2-Air Annular Rotating Detonation Combustor

Three-dimensional Large Eddy Simulations (LES) are conducted on a non-premixed hydrogen-air annular rotating detonation combustor (RDC). A 22-step finite-rate chemistry reaction mechanism and a flow solver previously developed for high-speed reacting flow are used to perform the LES’. The selected case is an RDC designed by the US Air Force Research Laboratory and has been studied experimentally a