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Architectural design is a process of creative problem solving, moreover architects manage not only information about the building but also about the user organisation. Therefore, information systems for architectural design must support the development of new ideas and concepts, and must be able to handle both building and user data. The paper presents two recently developed prototype applicationsArchitectural design is a process of creative problem solving, moreover architects manage not only information about the building but also about the user organisation. Therefore, information systems for architectural design must support the development of new ideas and concepts, and must be able to handle both building and user data. The paper presents two recently developed prototype applications

There are two main routes for customers of industrialized house building to follow: either rigid platforms offering preconfigured products, often called ‘type houses’, or more flexible platforms open to customization. The problem in customization is to link customer requirements with system opportunities. In axiomatic design processes, this problem is understood as the transformation of customer rThere are two main routes for customers of industrialized house building to follow: either rigid platforms offering preconfigured products, often called ‘type houses’, or more flexible platforms open to customization. The problem in customization is to link customer requirements with system opportunities. In axiomatic design processes, this problem is understood as the transformation of customer r

The presentation introduces the concept of 'sustainable welfare'. Central to this concept is the notion of human needs and how these could be satisfied for everyone, now and in future, within planetary limits and without economic growth. The contribution presents recent research results, addresses structural challenges to degrowth and sustainable welfare such as the hegemony of the growth paradigm

Since Herman Daly’s original writings, growth-critical scholarship has frequently referred to the policy tools of minimum income schemes and maximum limits on incomes and wealth to tackle social inequality in a degrowth transition. However, while there is a broad discussion of minimum income schemes within the degrowth research community and beyond, not much has been produced on maximum limits on

Denna avhandling undersöker retorisk flertydighet som en egenskap hos uttryck som adresserar sammansatta, heterogena publiker. Avhandlingens syfte är att utveckla konceptuella verktyg för analysen av flertydiga kommunikativa handlingar, för att undersöka vilka utfall de kan möjliggöra. Avhandlingens utgångspunkt är att uttryck är meningsfulla och fundamentalt sociala handlingar, som alltid är en dThis thesis is an inquiry into rhetorical ambiguity as a property of utterances addressing composite, heterogeneous audiences. The purpose is to develop conceptual tools to analyse ambiguous communicative acts for the outcomes they make possible. The thesis proceeds from the assumption that utterances are purposeful and fundamentally social acts, always part of an ongoing social dialogue. As such,

Authors of a recent paper demonstrate that, like ERMES (ER-mitochondria encounter structure) in fungal cells, PDZD8 (PDZ domain containing 8) tethers mitochondria to the ER in mammalian cells. However, identifying PDZD8 as a "functional ortholog" of yeast Mmm1 (maintenance of mitochondrial morphology protein 1) is at odds with the phylogenetic data. PDZD8 and Mmm1 are paralogs, not orthologs, whic

The purpose of this article is to explore the intersections between genes, the body and the lived experience of a genetic disease. This article is based on empirical material from a study on how individuals affected by Huntington’s disease experience their everyday life. This study identified two themes that represent and capture the experience of the affected individuals. The themes are (1) notic

Recension av Svante Nordin, Hitlers München.

Artikeln handlar om vad den nu lagfästa proportionalitetsprincipen i den nya förvaltningslagen innebär. I artikeln beskrivs mot bakgrund av tidigare forskning hur principen, med ursprung i tysk förvaltningsrätt, har fått insteg i svensk lagstiftning och utvecklats genom praxis, delvis med hjälp av europarätten. Vidare undersöks i vilken mån den nya regleringen uppfyller lagstiftningens syfte att f

The linear ubiquitin chain assembly complex (LUBAC) is required for optimal gene activation and prevention of cell death upon activation of immune receptors, including TNFR1 1 . Deficiency in the LUBAC components SHARPIN or HOIP in mice results in severe inflammation in adulthood or embryonic lethality, respectively, owing to deregulation of TNFR1-mediated cell death 2-8 . In humans, deficiency in

For a probability measure with compact and non-polar support in the complex plane we relate dynamical properties of the associated sequence of orthogonal polynomials {P n } to properties of the support. More precisely we relate the Julia set of P n to the outer boundary of the support, the filled Julia set to the polynomial convex hull K of the support, and the Green’s function associated with P n