Sökresultat

(conference presentation at the "Svensk gnosis genom tiderna"/"Swedish Gnosis through the ages" conference, Stockholm, April 2025)

BACKGROUND: The predictive value of atrial conduction abnormalities, reflected by P-wave indices (PWI), and their association with biomarkers signaling fibrosis for the development of atrial fibrillation (AF) in patients with heart failure (HF) remains underexplored.OBJECTIVE: We aim to investigate the associations between PWI, fibrosis biomarkers, and the risk of incident AF in patients with HF.M

The South-to-North Water Diversion Project (SNWDP), the world’s largest water transfer initiative, is designed to address northern China’s acute water scarcity by diverting approximately 45 km3 of water annually from the south through three major routes, with completion targeted for 2050. This review demonstrates that the SNWDP has already improved water security for over 150 million people, stabi

The invention pertains to a process for preparing a random co- poly(hydroxycarbonate) comprising reacting a 6-membered di-cyclic carbonate with a polyol, or a monohydric alcohol, via a ring-opening polymerization (ROP) by catalytic control for carbonate unit formation, in the presence of a catalyst, through a ring- opening polymerization reaction. Also, the invention pertains to a random co- poly(

The invention pertains to a process for preparing a random co-poly(urethane-carbonate) comprising reacting a 6-membered di-cyclic carbonate with a polyamine via a ring- opening polymerization (ROP) by catalytic control for carbonate unit formation, in the presence of a catalyst, through a ring-opening polymerization reaction. Also, the invention pertains to a random co-poly(urethane-carbonate) bei

FLT3 is a critical prognostic marker in acute myeloid leukemia (AML) due to its high frequency of mutation. Primary mutations in FLT3 include point mutations or deletions in the tyrosine kinase domain (TKD) and internal tandem duplications (ITD) in the juxtamembrane (JM) region. These mutations lead to ligand-independent activation, disrupting the JM region and kinase domain interaction, resulting

Homelessness has increased significantly in Sweden since the early 1990s. A national survey of homelessness in 2023 showed that 27,383 people were in one of the four homelessness situations that are used in Sweden, namely 1) Acute homelessness, 2) Institutional and supported housing, 3) Long-term housing organised by the municipality and 4) Short-term accommodation arranged on one’s own. These homHomelessness has increased significantly in Sweden since the early 1990s. A national surveyof homelessness in 2023 showed that 27,383 people were in one of the four homelessnesssituations that are recognised in Sweden, namely: (a) acute homelessness; (b) institutional orsupported housing; (c) long-term housing organised by a municipality; and (d) short-termaccommodation arranged by people themselv

FN:s oberoende kommission har slagit fast att ett folkmord pågår i Gaza. Trots det vägrar Lunds universitetsledning att ompröva sina samarbeten med israeliska universitet och företag med kopplingar till vapenindustrin.Lunds universitet måste nu ta ansvar och avbryta dessa samarbeten – eller erkänna att man väljer att blunda för brott mot mänskligheten. Det skriver 16 forskare från Lunds universite

Polyoxometalates (POMs) and their instrinsic discrete nature has enabled them to support a wide range of research spanning solution-speciation chemistry, biological/medical assays, catalytic processes and fundamental crystallography. The structure-property relationship of POMs are a consequence of their constiuent metal atoms, which inevitably are formed under specific regimes - for simplicity, ac

Circularity metrics simplify complex systems, and trade-offs between simplicity, scope, and usability introduce unavoidable limitations. We revisit the Ellen MacArthur Foundation’s Material Circularity Indicator (MCI) to identify opportunities for a more accurate, comprehensive, reliable measure of circularity. Although widely used and highly regarded, the MCI exhibits limitations and methodologic

INTRODUCTION: While the characteristics and medical management of patients treated with long-term oxygen therapy (LTOT) have transformed during the last decades, the evidence base for LTOT itself remains largely unchanged. This study aimed to compare the risk of hospitalization and death among hypoxemic patients discontinuing LTOT, with that of controls continuing therapy.METHODS: This was a retro

Glucuronidation is the major phase II biotransformation reaction that facilitates the clearance of exogenous compounds from the human body. Glucuronidated metabolites have been investigated in urine samples at a broad scale; however, their characterization in other human biospecimens is underexplored. Our study has now performed a comprehensive profiling of glucuronides in plasma, fecal, and cereb

Background: Peritoneal recurrence (PREC) following nephrectomy for localized renal cancer (RCC) is rare. Our objective was to report a multicenter analysis of PREC to analyze incidence, treatment, survival and risk factors. Methods: Between 1987 and 2023, patients with PREC following radical or partial nephrectomy (PN) for localized RCC across ten European institutions (UroCCR, NKI, IRCCS, Foch an

Speaking in poor acoustic conditions constitutes a risk factor for voice disorders. This study investigated how speaker’s comfort and vocal effort were affected during short speech tasks in four different room acoustic configurations. Voice recordings of the speech tasks and self-evaluations of the speaker’s comfort were collected from 15 participants in four room acoustic configurations as part o

Scope: Vascular graft or endograft infection (VGEI) is a severe complication requiring a multidisciplinary approach combining surgery and antimicrobial therapy. This study aimed to develop expert consensus on the management and follow-up of VGEI, with a focus on antimicrobial strategies. Methods: A modified Delphi method was conducted to reach consensus on key aspects of VGEI care, including antim

Aging is the primary risk factor for most neurodegenerative diseases, yet the cell-type-specific progression of brain aging remains poorly understood. Here, human cell-type-specific transcriptomic aging clocks are developed using high-quality single-nucleus RNA sequencing data from post mortem human prefrontal cortex tissue of 31 donors aged 18–94 years, encompassing 73,941 high-quality nuclei. Di