Molecular imprinting, method for creating artificial receptors that are mimics of biological antibodies and receptors, is based on the concept of creating substrate-specific recognition sites in polymeric matrices by means of template polymerisation. The polymeric receptors produced display favourable binding characteristics, such as high affinity and specificity towards the substrate molecules. C

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Most of the recombinant proteins produced nowadays are fused to affinity tags, in order to facilitate their purification through affinity chromato-graphy. Out the different tags available, poly-histidine tags are among the most commonly used and can help purification through immobilised metal ion affinity chromatography (IMAC). In this thesis, we present different metal binding tags, and their af

This paper deals with the joint estimation of spatial mode shapes and temporal frequencies from transient vibrations measured by a uniform circular array of sensors encircling a cross-section of a cylinder. The geometry allows each 2D mode to be interpreted as two real planar waves impinging from mirrored directions with respect to the broadside of a uniform linear array. Algorithms for joint esti

It is shown how tilt anisoplanatism in laser-supported multi-conjugatedadaptive optics (MCAO) systems can be a) predicted from a prioriknowledge, b) compensated using additional natural guide stars (NGS),and c) estimated in real time from control loop data to allow PSFretrieval. As a consequence of the problems associated with retrievingatmospheric tip and tilt from laser guide star (LGS) measurem

As emphasized by Jeremy Bentham and the analytical school, logical consistency is a requirement for rational legislation. For understanding consistency between norms, a logical scrutiny of normative conflicts is needed. In our paper, a framework for the fine structure of such conflicts is introduced and explained. “Normative conflict” is defined relative the framework and different types of confli

Artikeln visar statistik och diskuterar möjligheterna och begränsningarna i äldres tillgänglighet till i IT-samhället under senare delen av 1990-talet. Resultatet från en intervjuundersökning (n=186)visar att äldre IT-användare kan kategoriseras i beroende, akriva och avancerade användare och att detta formas av tillgången, förmågan, förväntningarna, självbilden och dagliga restriktioner (sociala

Popular Abstract in Swedish Magsäcken är ett av kroppens största peptidhormon-producerande organ. Peptid-hormon härifrån är inte bara viktiga för att reglera olika fysiologiska funktioner i magsäcken t.ex. saltsyrasekretion och motilitet, utan också för andra funktioner i kroppen. Fortfarande vet vi mycket lite om de hormon som produceras i magsäcken. Några av de hormon man identifierat har okändaThe novel gastric hormone ghrelin was discovered by virtue of its ability to release growth hormone (GH) via interaction with the so-called GH-secretagogue receptor (GHS-R). Earlier only synthetic agents were known to bind with the GHS-R, hence, ghrelin is the first identified endogenous ligand. GHS-R occurs in the pituitary and hypothalamus but also in several peripheral tissues, suggesting the i