Aromatic l-amino acid decarboxylase (AADC) cells are widely distributed in the spinal cord, and their functions are largely unknown. We have previously found that AADC cells in the spinal cord could increase their ability to produce serotonin (5-hydroxytryptamine) from 5-hydroxytryptophan after spinal cord injury (SCI). Because AADC is a common enzyme catalyzing 5-hydroxytryptophan to serotonin an

Background: Type 2 diabetes and its cardiovascular disease complications are the major public health threats of our century. Although physical activity and dietary changes are the cornerstones in prevention of diabetes, their broad implementation is not elementary and other complementary lifestyle regimens are needed. Summary: Vasopressin (VP) is the main regulator of body water homeostasis, and a

Purpose To develop an infrastructure for structured and automated collection of interoperable radiation therapy (RT) data into a national clinical quality registry. Materials and methods The present study was initiated in 2012 with the participation of seven of the 15 hospital departments delivering RT in Sweden. A national RT nomenclature and a database for structured unified storage of RT data a

Nutritional management of blood glucose levels is a strategic target in the prevention and management of type 2 diabetes mellitus (T2DM). To implement such an approach, it is essential to understand the effect of food on glycemic regulation and on the underlying metabolic derangements. This comprehensive review summarizes the results from human dietary interventions exploring the impact of dietary

Biblioteks- och informationsvetenskaplig forskning har visat hur infrastruk-turer och data inte är neutrala utan bidrar till att forma både det som de re-presenterar och sammanhangen där de används. Vi utgår från dessa insik-ter och diskuterar i artikeln en nyhetsrapportering från november 2015 som handlade om en eventuell förändring av abortgränsen i Sverige. Registerda-ta från Svenskt Neonatalt Library and information studies research has shown how infrastructures and data are, contrary to common perceptions, not neutral but take part in sha- ping what they represent and the contexts in which they are used. Starting off from these insights we discuss Swedish media reports from November 2015 about a possible alteration of the abortion limit due to recent findings in neonatal care and rese

We investigated phonon-phonon interactions in photoexcited single-crystalline graphite by ultrafast electron diffraction. Transient electron diffraction profiles from a 35 nm graphite film were observed following laser excitation. Changes in intensities of diffraction spots revealed a two-exponential relaxation process with

We report on a theoretical study of the electronic structures of the [1 1 1]-oriented, freestanding, zincblende InAs and InP nanowires with hexagonal cross sections by means of an atomistic sp3s∗, spinorbit interaction included, nearest-neighbor, tight-binding method. The band structures and the band state wave functions of these nanowires are calculated and the symmetry properties of the bands an

People who live in brown bear areas often fear encounters with these animals. This article evaluated the potential effect of exposure to bears and their habitats on human fear of brown bears using the modeling of appropriate behavior when close to bears. In a within-subject design, 25 persons who reported to be fearful of brown bears participated in a guided walk approaching approximately 50 m of

Objective: Iron isomaltoside (Monofer®) is a high-dose intravenous iron preparation with good tolerability and efficacy in inflammatory bowel disease (IBD) patients with iron deficiency anaemia (IDA). This trial evaluates the safety and efficacy, including effect on intact fibroblast growth factor 23 (iFGF23) of a high single dose and cumulative doses of iron isomaltoside in IBD patients with IDA.

Calcium-rich supernovae (SNe) represent a significant challenge for our understanding of the fates of stellar systems. They are less luminous than other SN types and they evolve more rapidly to reveal nebular spectra dominated by strong calcium lines with weak or absent signatures of other intermediate-and iron-group elements, which are seen in other SNe. Strikingly, their explosion sites also mar

Four species of Coleoptera, not previously reported from Sweden are presented; Euconnus campestris (Schaufuss, 1866) (Staphylinidae: Scydmaeninae), Scopaeus ryei Wollaston, 1872 (Staphylinidae: Paederinae), Acritus homoeopaticus Wollaston, 1857 (Histeridae) and Ephistemus reitteri Casey, 1900 (Cryptophagidae). They have all been collected using car net in an area next to the lake Häckeberga in Sca

Background and Purpose - Orosomucoid (α-1-acid glycoprotein) is an acute-phase protein that has been implicated in anti-inflammatory, immunomodulating, and angiogenic pathways. Orosomucoid has also been associated with coronary disease and stroke. The relationship between orosomucoid, carotid plaque, and stroke incidence were explored in this study. Methods - Plasma levels of orosomucoid were asse

Platelet P-selectin and activated glycoprotein IIb–IIIa (GPIIb–IIIa) are markers of platelet activation and mediates platelet aggregation. Prasugrel (Pras) 5 mg may be used in very elderly (VE) acute coronary syndrome (ACS) patients undergoing PCI, but its effect on platelet P-selectin and activated GPIIb–IIIa in those patients is not known. Stable ACS patients, VE (78 ± 5 years, n = 23) and non-e

The transition from a fossil fuel-based energy system to a renewable one has emerged as a priority for many governments. This, in turn, has facilitated a rapid increase in renewable energy investments. However, this development raises important questions about the sustainability of energy governance when it comes to access and control of energy, public participation and transparency. In this artic

Background: Spirometric diagnosis of chronic obstructive pulmonary disease (COPD) is based on the ratio of forced expiratory volume in 1 second (FEV1)/vital capacity (VC), either as a fixed value 1/VC ratio in a general population setting. The second aim was to evaluate the characteristics of subjects with COPD who obtained a higher SVC than FVC. Methods: Subjects (n=1,050) aged 50-64 years were i

Young people with psychiatric disabilities may require support in structuring their everyday life. To learn more about the relevance of day centres in this respect, this study aimed to examine the experiences of young people with psychiatric disabilities. A particular focus was on the perceptions of meaningful occupation when visiting day centres, their reasons for not choosing this option when gi

Background: Stress-related disorders are a public health problem and represent a significant burden to individuals and society. It is, therefore, of importance to regard stress in a wider context and identify risk factors not only at work but in all occupations in everyday life, to prevent ill health. Aim/objective: The aim of this study was to examine potential associations between everyday occup

Objectives: Audiologists provide professional contact and support between appointments to clients with hearing impairment using telephone and e-mail, but more advanced and flexible technological platforms are also possible. The present study aimed to evaluate the clinical application of an Internet-based support system for audiologists and their first-time hearing aid clients. Design: An Internet-