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Evidence associates cardiovascular risk factors with unfavorable systemic and neuro-inflammation and cognitive decline in the elderly. Cardiovascular therapeutics (e.g., statins and anti-hypertensives) possess immune-modulatory functions in parallel to their cholesterol- or blood pressure (BP)-lowering properties. How their ability to modify immune responses affects cognitive function is unknown.
Alltsedan Kockums huvudkontor sträckte sig över varvets kranar har skyskraporna i Malmö genererat intensiva debatter om vad staden är och, inte minst, vad den borde vara. Skyskrapsprojekt har om och om igen varit del av hur stadens identitet vuxit fram: Sydsvenskanhuset, Kronprinsen, Triangeln och senare Turning Torso och Malmö Live är några exempel.I Malmhattanism undersöker arkitekturforskaren F
Infectious diseases are an existential health threat, potentiated by emerging and re-emerging viruses and increasing bacterial antibiotic resistance. Targeted treatment of infectious diseases re-quires precision diagnostics, especially in cases where broad-range therapeutics such as antibiotics fail. There is thus an increasing need for new approaches to develop sensitive and specific in vitro dia
The directive to close the dumpsite in Kisumu, Kenya has made the search for alternative solid waste treatment and disposal technologies urgent. The aim of this research is to support the decision-making process by analyzing multiple socioeconomic and environmental parameters of salient solid waste treatment options. We used multi-criteria analysis to assess and compare anaerobic digestion, sanita
BackgroundThere is a continuous and dynamic discussion on artificial intelligence (AI) in present-day society. AI is expected to impact on healthcare processes and could contribute to a more sustainable use of resources allocated to healthcare in the future. The aim for this work was to establish a foundation for a Swedish perspective on the potential effect of AI on the medical physics profession
Background: Unhealthy lifestyle habits, low socioeconomic status, and low self-rated health (SRH) increase the risk of non-communicable diseases, such as cardiovascular disease. There are shared risk factors between arterial and venous thrombosis (VTE), and they predispose for one another. Targeted health dialogues have proven to be an effective method for finding those at risk. The Swedish health
SARS-CoV-2 has spread rapidly worldwide, causing the COVID-19 pandemic. Platelet activation and platelet-leukocyte complex formation are proposed to contribute to disease progression. Here, we report platelet and leukocyte activation during acute and convalescent COVID-19 in patients recruited between May-July 2020. Blood samples were analyzed by flow cytometry and ELISA using paired comparison be
Objectives The literature on patient safety in psychiatry has not been explored systematically in terms of what interventions are used, how they are used, and what type of (preventable) harm is targeted. The aims of this scoping review are to explore patient safety strategies used in psychiatry and determine how they construct the notion of preventable harm.Method A scoping review of literature on
Keeping the umbilical cord intact after delivery facilitates transition from fetal to neonatal circulation and allows a placental transfusion of a considerable amount of blood. A delay of at least 3 minutes improves neurodevelopmental outcomes in term infants. Although regarded as common sense and practiced by many midwives, implementation of delayed cord clamping into practice has been unduly slo
OBJECTIVES: The safety of generic substitution of antiseizure drugs (ASDs) has been questioned for many years. This study aimed to identify physicians' attitudes to the generic substitution of ASDs in epilepsy and which factors were of significance when deciding on compound substitutions.MATERIAL AND METHODS: A cross-sectional web-based survey was sent to neurologists and neurology residents in pu
Our purpose in hosting the National First Peoples Gathering on Climate Change (the Gathering) was to celebrate, learn from and enhance First Peoples-led climate action. We set out to strengthen kinships, cultural identity and well-being, and to strengthen caring for Country by using both Indigenous and scientific knowledge. The Gathering supported this overall purpose through five aims:• Bring Tra
In risk-related research of fire safety engineering, metamodels are often applied to approximate the results of complex fire and evacuation simulations. This approximation may cause epistemic uncertainties, and the inherent uncertainties of evacuation simulations may lead to aleatory uncertainties. However, neither the epistemic ‘metamodel uncertainty’ nor the aleatory ‘inherent uncertainty’ have
This paper contains a description, an alignment and a joint approach for technology readiness development with a three phases support of decision value analyses. The three phases are separated into the decision value forecasting, decision value analysis and the technology value quantification supporting the technological concept formulation and experimental testing, the prototype development and t
Support structures of offshore wind turbines are subject to cyclic stresses generated by different time-variant random loadings such as wind, waves, and currents in combination with the excitation by the rotor. In the design phase, the cyclic demand on wind turbine support structure is calculated and forecasted with semi or fully probabilistic engineering models. In some cases, additional cyclic s
The temporality of agency plays a fundamental role in regional development but has received little attention in economic geography and regional studies. This paper zooms in on two aspects of temporality: the temporality of intentions and the temporality of consequences. The former refers to actors’ perception and valuation of opportunities in the near and distant future, whereas the latter refers
Accurate and timely monitoring of streamflow and its variation is crucial for water resources management in watersheds. This study aimed at evaluating the performance of two process-driven conceptual rainfall-runoff models (HBV: Hydrologiska Byråns Vattenbalansavdelning, and NRECA: Non Recorded Catchment Areas) and seven hybrid models based on three artificial intelligence (AI) methods (adaptive n
Christina Pipers (1673-1752) pietistiska tro, och hur den uttrycks i hennes liv, särskilt som änka.
Anti-Black Racism is still very present in Yemen, with a discriminatory caste system that is based on skin colour. Nevertheless, there are initiatives and solutions being put forward to combat this and ways in which awareness is being raised. This paper seeks to explore the dynamics of anti-Black racism in Yemen and how resistance against this is expressed, as well as the obstacles activists face
This study aimed to investigate the responses of university students (late adolescents) about their conceptualization of a child, exploring the characteristics they associate with being a child. The study was conducted in two phases. In phase 1, responses to one open-ended question, what is a child? (N=75), were analyzed using qualitative content analysis. In phase 2, students (N=90) filled in an
