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Arbetsgivarbegreppet och arbetsrättsligt ansvar i komplexa arbetsorganisationer : En studie av anställningsskydd, diskriminering och arbetsmiljö
Waste management in Zaatari refugee camp / Mafraq-Jordan
Jordan population have increased 3 million in the last five years. 1.5Million are refugees from Syria. 800 thousand are inside refugeecamps in the northern part of Jordan. 100 thousand are situated inZaatari camp which is located 10 kilometres east of Mafraq city. Thisenormous influx increased solid waste volume generated by 480 tonsdaily. The additional waste generation has exacerbated pre-existi
Waste-to-Energy in Jordan - Potential and Challenges
Application of Response Surface Methodology for Study of Fluxes Effects in Fusion of Ashes from Mineral Coal
The present study uses RSM (Response Surface Methodology) to verify the fusibility of bottom ash from coal industry, and efficient flux between, calcium oxide (CaO), lithium oxide (Li2O) and sodium oxide (Na2O). The bottom ashes,have demonstrated the possibility to be used in the development of glass-ceramics, and glassy materials, due to the presence of high concentrations of aluminum silicates.
Epilepsy surgery in the Nordic countries
Tailoring the Optical Response of III-V Nanowire Arrays
Semiconductor nanowires show a great deal of promise for applications in a widerange of important fields, including photovoltaics, biomedicine, and informationtechnology. Developing these exciting applications is strongly dependent onunderstanding the fundamental properties of nanowires, such as their opticalresonances and absorption spectra. In this thesis we explore optical absorption spectra of
Anterograde and retrograde regulation of nuclear genes encoding mitochondrial proteins during growth, development, and stress
Mitochondrial biogenesis and function in plants require the expression of over 1000 nuclear genes encoding mitochondrial proteins (NGEMPs). The expression of these genes is regulated by tissue-specific, developmental, internal, and external stimuli that result in a dynamic organelle involved in both metabolic and a variety of signaling processes. Although the metabolic and biosynthetic machinery o
The membrane-bound NAC transcription factor ANAC013 functions in mitochondrial retrograde regulation of the oxidative stress response in Arabidopsis
Upon disturbance of their function by stress, mitochondria can signal to the nucleus to steer the expression of responsive genes. This mitochondria-to-nucleus communication is often referred to as mitochondrial retrograde regulation (MRR). Although reactive oxygen species and calcium are likely candidate signaling molecules for MRR, the protein signaling components in plants remain largely unknown
A membrane-bound NAC transcription factor, ANAC017, mediates mitochondrial retrograde signaling in Arabidopsis
Plants require daily coordinated regulation of energy metabolism for optimal growth and survival and therefore need to integrate cellular responses with both mitochondrial and plastid retrograde signaling. Using a forward genetic screen to characterize regulators of alternative oxidase1a (rao) mutants, we identified RAO2/Arabidopsis NAC domain-containing protein17 (ANAC017) as a direct positive re
AtWRKY40 and AtWRKY63 modulate the expression of stress-responsive nuclear genes encoding mitochondrial and chloroplast proteins
The expression of a variety of nuclear genes encoding mitochondrial proteins is known to adapt to changes in environmental conditions and retrograde signaling. The presence of putative WRKY transcription factor binding sites (W-boxes) in the promoters of many of these genes prompted a screen of 72 annotated WRKY factors in the Arabidopsis (Arabidopsis thaliana) genome for regulators of transcripts
Comparison of transcriptional changes to chloroplast and mitochondrial perturbations reveals common and specific responses in Arabidopsis
Throughout the life of a plant, the biogenesis and fine-tuning of energy organelles is essential both under normal growth and stress conditions. Communication from organelle to nucleus is essential to adapt gene regulation and protein synthesis specifically to the current needs of the plant. This organelle-to-nuclear communication is termed retrograde signaling and has been studied extensively ove
LETM proteins play a role in the accumulation of mitochondrially encoded proteins in Arabidopsis thaliana and AtLETM2 displays parent of origin effects
The Arabidopsis thaliana genome contains two genes with homology to the mitochondrial protein LETM1 (leucine zipper-EF-hand-containing transmembrane protein). Inactivation of both genes, Atletm1 and Atletm2, together is lethal. Plants that are hemizygous for AtLETM2 and homozygous for Atletm1 (letm1(-/-) LETM2(+/-)) displayed a mild retarded growth phenotype during early seedling growth. It was sh
REDOX regulation of mitochondrial function in plants
Mitochondrial components dynamically change in response to environmental and developmental cues. However, the regulatory pathways that underlie these changes are largely unknown. A global analysis of changes in mitochondrial components at the transcript, protein and metabolite levels was undertaken, to gain a greater insight into how mitochondrial functions are regulated and respond to various int
TCP transcription factors link the regulation of genes encoding mitochondrial proteins with the circadian clock in Arabidopsis thaliana
Diurnal regulation of transcripts encoding proteins located in mitochondria, plastids, and peroxisomes is important for adaptation of organelle biogenesis and metabolism to meet cellular requirements. We show this regulation is related to diurnal changes in promoter activities and the presence of specific cis-acting regulatory elements in the proximal promoter region [TGGGC(C/T)], previously defin
Perturbation of indole-3-butyric acid homeostasis by the UDP-glucosyltransferase UGT74E2 modulates Arabidopsis architecture and water stress tolerance
Reactive oxygen species and redox signaling undergo synergistic and antagonistic interactions with phytohormones to regulate protective responses of plants against biotic and abiotic stresses. However, molecular insight into the nature of this crosstalk remains scarce. We demonstrate that the hydrogen peroxide-responsive UDP-glucosyltransferase UGT74E2 of Arabidopsis thaliana is involved in the mo
Prohibitins : mitochondrial partners in development and stress response
Twelve years after their discovery in plants, prohibitins (PHBs) have retained their status as some of the most enigmatic mitochondrial proteins. Although the original hypothesis that PHBs act as negative cell cycle regulators has lost its impetus in plants, the essential molecular function(s) PHB complexes perform in the inner mitochondrial membrane are now beginning to be understood. We review t
Defining the mitochondrial stress response in Arabidopsis thaliana
To obtain a global overview of how mitochondria respond to stress, we aimed to define the plant mitochondrial stress response (MSR). By combining a set of 1196 Arabidopsis thaliana genes that putatively encode mitochondrial proteins with 16 microarray experiments on stress-related conditions, 45 nuclear encoded genes were defined as widely stress-responsive. Using green fluorescent protein (GFP) f
Developmental stage specificity and the role of mitochondrial metabolism in the response of Arabidopsis leaves to prolonged mild osmotic stress
When subjected to stress, plants reprogram their growth by largely unknown mechanisms. To provide insights into this process, the growth of Arabidopsis (Arabidopsis thaliana) leaves that develop under mild osmotic stress was studied. Early during leaf development, cell number and size were reduced by stress, but growth was remarkably adaptable, as division and expansion rates were identical to con
The transcription factor ABI4 is a regulator of mitochondrial retrograde expression of ALTERNATIVE OXIDASE1a
Plant cells integrate signals from external sources and from organelles to regulate gene expression, referred to as anterograde and retrograde signaling, respectively. Functional characterization of the promoter of ALTERNATIVE OXIDASE1a (AOX1a) from Arabidopsis (Arabidopsis thaliana), a marker for mitochondrial retrograde response, was carried out by testing the ability of the AOX1a promoter to dr