Olanzapine and quetiapine are routinely used off-label at lower doses, though it remains unclear whether treatment is associated with mortality. Here, we examined the associations between low-dose olanzapine/quetiapine, defined as 5 mg/day of olanzapine equivalents (OE) with cardiometabolic mortality in a population-based, longitudinal cohort of individuals who sought specialized psychiatric servi

Det uppskattas att år 2050 kommer tio miljoner människor att dö av infektionersom inte kan behandlas på grund av att bakterier blivit resistenta ochdärmed gjort antibiotika ineffektiv. Denna typ av dystopier är en form avresor både bakåt och framåt i tiden, och där samhället beskrivs som någotannat än vad vi är vana vid. Tanken om en framtid utan antibiotika – enså kallad postantibiotisk era – går

Early ventricular tachycardia (VT) and ventricular fibrillation (VF) are associated with increased in-hospital mortality but do not influence the long-term prognosis in ST-elevation myocardial infarction (STEMI). Recent data advocate a differential approach to the type of arrhythmia and indicate long-term mortality hazard associated with monomorphic VT. We aimed to evaluate the prognostic value of

Biodegradable magnesium (Mg) alloys can revolutionize osteosynthesis, because they have mechanical properties similar to those of the bone, and degrade over time, avoiding the need of removal surgery. However, they are not yet routinely applied because their degradation behavior is not fully understood. In this study we have investigated and quantified the degradation and osseointegration behavior

Det uppskattas att år 2050 kommer tio miljoner människor att dö av infektionersom inte kan behandlas på grund av att bakterier blivit resistenta ochdärmed gjort antibiotika ineffektiv. Denna typ av dystopier är en form avresor både bakåt och framåt i tiden, och där samhället beskrivs som någotannat än vad vi är vana vid. Tanken om en framtid utan antibiotika – enså kallad postantibiotisk era – går

Purpose: Using observational and experimental designs, the purpose of this study was to explore if the power relation between the offender and the victim of incivility and the level of perceived severity of the incivility were associated with bystanders’ intentions to help when witnessing workplace incivility. Design/methodology/approach: In Study 1, 160 participants completed a questionnaire wher

A novel natural small molecule, voacangine (Voa), has been discovered as a potent antiangiogenic compound. Notably, Voa directly binds the kinase domain of the vascular endothelial growth factor receptor 2 (VEGFR2) and thereby inhibits downstream signaling. Herein, we developed synthetic small molecules based on the unique chemical structure of Voa that directly and specifically target and modulat

Recension av: Stefan Östersjö, 2021. Listening to the Other, 184 s. Leuven: Leuven University Press. ISBN: 978-94-6270-229-5.

In the past few decades, there has been a global trend of international harmonization of accounting standards, with many countries having either partially or completely replaced their national accounting standards with the International Financial Reporting Standards (IFRS). The intended goal is to remove the barriers that hinder investors when comparing accounting information of companies from dif

Prostate cancer bone metastasis is still not fully understood, and increased knowledge could aid in the development of better treatment options for patients in the future. This thesis focuses on microRNAs (miRNAs), which modulate gene expression in healthy and tumour cells. Using cell culture, animal and patient studies, we investigated the biological role of microRNA-96 (miR-96) and microRNA-379

The book comprises three parts: (1) a general presentation and analysis of the main relevant concepts: bioethics, human genetic engineering, eugenics, disability and, particularly, of the relations between these; (2) the analysis of two documents of the Council of Europe (the so called “Bioethics Convention” and its first protocol), and the reconstruction of the debates surrounding their primary c

Über sociale Differenzierung ist Georg Simmels erstes hauptsächlich der Soziologie gewidmetes Werk. Das Buch stellt Simmels Grundlegung der neuen Wissenschaft dar, ihrer Themen, Möglichkeiten, Grenzen, allgemeinen Begriffe und Annahmen. Soziale Differenzierung, Wechselwirkung, Individualisierung, Gruppe, Vergesellschaftung und Bewegung sind entscheidende, variable Begriffe dieses zwischen Grundleg

A heterocyclic chemical compound of formula (1) or (2) or a neutral or acidic salt thereof where the counter ion is LI+, Na+, K+, Mg2+, Ca2+, NH4+ or another pharmacologically acceptable positively charged inorganic or organic ion or any combination thereof. The compound contains B, Si, N, P, S or Se in the ring structure.

Introduction. Underage drinking is associated with poor mental health. Early detection for risky alcohol use is recommended,although less implemented in adolescent care. +e objective of this study was to investigate the prevalence of risky alcohol use andpsychiatric comorbidity. Methods. Over a nine-month period, 145 eligible adolescents admitted to the child and adolescentemergency unit in Malmo,

Affective and anxiety diagnoses are common in older people with intellectual disability (ID). The aim was to describe support and social services for older people with ID and affective and/or anxiety diagnoses, also to investigate in this study group the association between support and social services and frailty factors in terms of specialist healthcare utilisation, multimorbidity, polypharmacy,

The aim of this study was to describe the social care provided for different age groups of people with intellectual disability, 55 years or above, and to investigate the association between such care and frailty factors for those with diagnosed level of intellectual disabilities. Descriptive and logistic regression analyses were used. Commonest forms of social care among the 7936 people were Resid