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Cost of Illness for Five Major Foodborne Illnesses and Sequelae in Sweden

ObjectivesThe main objective of this study was to derive cost estimates of five major foodborne illnesses (campylobacteriosis, salmonellosis, enterohemorrhagic Escherichia coli (EHEC), yersiniosis and shigellosis) in Sweden. These estimates provide a necessary contribution to perform future cost-benefit analyses aimed at reducing the burden of foodborne disease. A secondary aim was to obtain estim

Genomic Profiles of Neuroblastoma Associated With Opsoclonus Myoclonus Syndrome

Opsoclonus myoclonus syndrome (OMS), often called "dancing eyed syndrome," is a rare neurological condition associated with neuroblastoma in the majority of all childhood cases. Genomic copy number profiles have shown to be of prognostic significance for neuroblastoma patients. The aim of this retrospective multicenter study was to analyze the genomic copy number profiles of tumors from children w

LSC - 2017 - Hippo-YAP/TAZ signaling is deranged in IPF

Objective: Idiopathic pulmonary fibrosis (IPF) is a devastating disease with no cure and is characterized by deranged epithelial repair, myofibroblast activation, and excess deposition of extracellular matrix. Yes associated protein (YAP) and transcriptional co-regulator with PDZ-binding domain(TAZ), co-transcriptional activators of the Hippo pathway and proto-oncogenes, were recently found to be

Rescue Effect Inherited in Colony Formation Assays Affects Radiation Response

It is well known that nonirradiated cells can exhibit radiation damage (bystander effect), and recent findings have shown that nonirradiated cells may help protect irradiated cells (rescue effect). These findings call into question the traditional view of radiation response: cells cannot be envisioned as isolated units. Here, we investigated traditional colony formation assays to determine if they

Characteristics of BVOC emissions from a Swedish boreal forest : Using chambers to capture biogenic volatile organic compounds (BVOCs) from trees and forest floor

Plant-emitted biogenic volatile organic compounds (BVOCs) are a large group of hydrocarbons released by plant leaves, bark, flowers and fruits into the atmosphere and from plant roots into the soil. BVOCs have important physiological and ecological functions, such as mediating within-plant and plant-plant communication, defense against herbivores attack, protection against heat or other oxidative

Physical neglect during childhood alters white matter connectivity in healthy young males

Background: Childhood adversity (CA) leads to greater vulnerability for psychopathology by causing structural as well as functional brain abnormalities. Recent findings on gray matter effects point towards the importance of identifying CA outcome as a function of different CA types, varying in the dimensions of threat and deprivation. Using diffusion tensor imaging, we investigate whether differen