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Topological superconductivity in semiconductor-superconductor-magnetic-insulator heterostructures

Hybrid superconductor-semiconductor heterostructures are promising platforms for realizing topological superconductors and exploring Majorana bound state physics. Motivated by recent experimental progress, we theoretically study how magnetic insulators offer an alternative to the use of external magnetic fields for reaching the topological regime. We consider different setups, where (1) the magnet

Effects of TiN Top Electrode Texturing on Ferroelectricity in Hf1-xZrxO2

Ferroelectric memories based on hafnium oxide are an attractive alternative to conventional memory technologies due to their scalability and energy efficiency. However, there are still many open questions regarding the optimal material stack and processing conditions for reliable device performance. Here, we report on the impact of the sputtering process conditions of the commonly used TiN top ele

Efficacy of an ACT and Compassion-Based eHealth Program for Self-Management of Chronic Pain (iACTwithPain) : Study Protocol for a Randomized Controlled Trial

Background: Chronic pain (CP) has serious medical and social consequences and leads to economic burden that threatens the sustainability of healthcare services. Thus, optimized management of pain tools to support CP patients in adjusting to their condition and improving their quality of life is timely. Although acceptance and commitment therapy (ACT) is considered an evidence-based psychological a

Prevention of ischemic myocardial contracture through hemodynamically controlled DCD

Purpose—Ischemic myocardial contracture (IMC) or ‘‘stoneheart’’ is a condition with rapid onset following circulatory death. It inhibits transplantability of hearts donated uponcirculatory death (DCD). We investigate the effectiveness of hemodynamic normalization upon withdrawal of life-sustaining therapy (WLST) in a large-animal controlled DCD model, with the hypothesis that reduction in cardiac

Improved Urinary Cortisol Metabolome in Addison Disease : A Prospective Trial of Dual-Release Hydrocortisone

CONTEXT: Oral once-daily dual-release hydrocortisone (DR-HC) replacement therapy has demonstrated an improved metabolic profile compared to conventional 3-times-daily (TID-HC) therapy among patients with primary adrenal insufficiency. This effect might be related to a more physiological cortisol profile, but also to a modified pattern of cortisol metabolism. OBJECTIVE: This work aimed to study cor

Body Temperature and Activity Rhythms Under Different Photoperiods in High Arctic Svalbard ptarmigan (Lagopus muta hyperborea)

Organisms use circadian rhythms to anticipate and exploit daily environmental oscillations. While circadian rhythms are of clear importance for inhabitants of tropic and temperate latitudes, its role for permanent residents of the polar regions is less well understood. The high Arctic Svalbard ptarmigan shows behavioral rhythmicity in presence of light-dark cycles but is arrhythmic during the pola

Factors Associated With the Decline of C-Peptide in a Cohort of Young Children Diagnosed With Type 1 Diabetes

CONTEXT: Understanding factors involved in the rate of C-peptide decline is needed to tailor therapies for type 1 diabetes (T1D). OBJECTIVE: Evaluate factors associated with rate of C-peptide decline after a T1D diagnosis in young children. DESIGN: Observational study. SETTING: Academic centers. PARTICIPANTS: A total of 57 participants from the Environmental Determinants of Diabetes in the Young (

Impact of surgical resection rate on survival in gastric cancer : nationwide study

BACKGROUND: There are marked geographical variations in the proportion of patients undergoing resection for gastric cancer. This study investigated the impact of resection rate on survival. METHODS: All patients with potentially curable gastric cancer between 2006 and 2017 were identified from the Swedish National Register of Oesophageal and Gastric Cancer. The annual resection rate was calculated

Routine versus selective intraoperative cholangiography during cholecystectomy : systematic review, meta-analysis and health economic model analysis of iatrogenic bile duct injury

BACKGROUND: Bile duct injury (BDI) is a severe complication following cholecystectomy. Early recognition and treatment of BDI has been shown to reduce costs and improve patients' quality of life. The aim of this study was to assess the effect and cost-effectiveness of routine versus selective intraoperative cholangiography (IOC) in cholecystectomy. METHODS: A systematic review and meta-analysis, c

Structure, Functions, and Physiological Roles of the Lipocalin α1-Microglobulin (A1M)

α1-microglobulin (A1M) is found in all vertebrates including humans. A1M was, together with retinol-binding protein and β-lactoglobulin, one of the three original lipocalins when the family first was proposed in 1985. A1M is described as an antioxidant and tissue cleaning protein with reductase, heme- and radical-binding activities. These biochemical properties are driven by a strongly electronega

Computational methods for querying and sampling the Twitter disinformation datasets

This study attempts to apply computational methods to the Twitter Election Integrity Datasets in order to derive a basic descriptive overview of this disinformation data, and to suggest some possible routes for developing these methods to address future research questions. The results indicate substantial variations in tweet frequency over time and geographical regions, as well as differences in r

Adipocytes Under Obese-Like Conditions Change Cell Cycle Distribution and Phosphorylation Profiles of Breast Cancer Cells : The Adipokine Receptor CAP1 Matters

Background: Obesity and associated metabolic conditions impact adipocyte functionality with potential consequences for breast cancer risk and prognosis, but contributing mechanisms remain to be understood. The adipokine receptor adenylyl cyclase-associated protein-1 (CAP1) has been implicated in the progression of breast cancer, but results are conflicting and the underlying molecular mechanisms a

Life satisfaction and adaptation in persons with Parkinson’s disease — A qualitative study

Persons with Parkinson’s disease (PD) need to adapt to their progressive disability to achieve and maintain a high degree of life satisfaction (LS), but little is known about the meaning of LS and adaptation. This study aimed to gain an in-depth understanding of the meaning of LS and adaptation in persons with PD. Open-ended in-depth interviews were performed with 13 persons diagnosed with PD, 9 w

The effect of nitrogen fertilization on tree growth, soil organic carbon and nitrogen leaching—a modeling study in a steep nitrogen deposition gradient in Sweden

Nitrogen (N) fertilization in forests has the potential to increase tree growth and carbon (C) sequestration, but it also means a risk of N leaching. Dynamic models can, if the important processes are well described, play an important role in assessing benefits and risks of nitrogen fertili-zation. The aim of this study was to test if the ForSAFE model is able to simulate correctly the effects of

Water quality changes during the first meter of managed aquifer recharge

The capacity of an artificial recharge field to alter organic matter and the bacterial flora of surface water was assessed by following changes in bacterial communities and composition of natural organic matter (NOM) over the first meter of infiltration depth. The sampling strategy applied in this study ensured that water samples consisted only of infiltrated water, excluding natural groundwater.

Moths are strongly attracted to ultraviolet and blue radiation

We carried out three choice experiments with 6116 nocturnal lepidopteran individuals (95 species, 7 families, 32 075 counts), each replicated 105 times during the seasons of 2 years. Moths were released indoors at the centre of a 10 × 10 m area with different lamps placed at each corner. In experiment 1, lamps emitted ultraviolet (UV) (peak at 365 nm), blue (450 nm), green (520 nm) or cool white (

Biomechanical properties of common carotid arteries assessed by circumferential 2D strain and β stiffness index in patients with ankylosing spondylitis

Objective. Ankylosing spondylitis (AS) is associated with an elevated risk of cardiovascular disease (CVD) related to atherosclerosis, preceded by arterial stiffness. We aimed to examine common carotid artery (CCA) biomechanical properties using ultrasound to calculate β stiffness index (indicating arterial stiffness) and, a more recently developed technique, 2-dimensional (2D) speckle tracking st