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Background: Myocardial injury activates the complement lectin pathway (LP) in acute coronary syndrome (ACS) and LP inhibition improved cardiac function in experimental studies, suggesting a direct pathogenic role. The clinical consequences of LP activation are insufficiently defined. We investigated how plasma levels of the LP activators mannose-binding lectin (MBL) and ficolin-2 (FCN2) relate to
For centuries there has been great interest in the dissolution of cellulose. Regarding industrial uses, water-based solvents remain the primary focus. It has long been known that concentrated solutions of sodium hydroxide can dissolve significant amounts of cellulose, but only at temperatures well below ambient conditions. This review discusses a general thermodynamic framework for cellulose disso
Background: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease targeting multiple organ systems, including the nervous system. The cerebellum may be involved in prevalent neuropsychiatric manifestations, such as depression and cognitive dysfunction, alongside other prevalent SLE manifestations such as pain and fatigue. We aim to compare cerebellar volumes in SLE patients and healt
Background: Adenosquamous carcinoma of the pancreas (ASCP) is a rare and aggressive subtype of pancreatic cancer with a dismal prognosis. Futility in ASCP has been inadequately studied. The aim is to assess the incidence of futility in ASCP cases within a European cohort. Methods: Retrospective, multicenter European study including all consecutive patients who underwent surgery for ASCP between 20
Natural enemies provide an important ecosystem service, limiting the population densities of insect pests in agricultural crops. In white clover (Trifolium repens L.) grown for seed production, the white clover seed weevil (Protapion fulvipes Geoffrey) is a major factor limiting seed yields. We explored the abundances and parasitism rates of P. fulvipes in relation to local field management and la
AIMS: Inflammasome activation has emerged as a promising therapeutic target to reduce residual cardiovascular (CV) risk in patients on guideline lipid-lowering therapy. IL-1β and IL-6 have been intensively studied, whereas the role of the inflammasome-related cytokine IL-18 has gained less attention. Here we aimed to assess the associations of IL-18 with risk of coronary events and severity of ath
AIMS: Aging is a major risk factor for cardiovascular disease (CVD) and is also linked to a functional decline of the immune system. B cells contribute to atherosclerosis progression by antibody secretion, antigen presentation and T-cell regulation. During aging, CD11c+CD21low B cells accumulate, but it is unclear whether these age-associated B cells (ABCs) are linked with incident cardiovascular
In the face of accelerating climate disruption, imagination is increasingly recognised as a vital but underdeveloped dimension of transformative change. This article explores immersive soundwalks—location-based audio narratives experienced through walking—as techniques of experiential climate futuring and affective engagement. Drawing on qualitative analysis of 62 reflection texts written by unive
Background Women identified with psychosocial risk factors are at higher risk of interventions during labour and birth and adverse maternal outcomes. Midwifery Continuity of Care (MCoC) reduces interventions and improves maternal outcomes among low-risk women; however, evidence on MCoC’s impact among women with psychosocial risk factors is limited. This study aimed to investigate whether an MCoC m
It has been said that the Kalmar Union, the union of Denmark, Norway, and Sweden between the late fourteenth and early sixteenth century, was typical of Europe at that time, but this has never been tested. A comparison is made here between the Kalmar Union, Poland–Lithuania, Castile–Aragon (Spain), and the Burgundian state, and particularly how they came into being. I con-sider four possible reaso
Airflow between rooms in an apartment is difficult to measure. Tracer gas methods can be used and will give good accuracy when fans are used to create well mixed air in each room. This will however affect the airflow between rooms with open doors. A series of experiments using single source tracer gas in 8 different apartments were performed in Sweden 2017-19. The time dependent concentration of t
Background: New long field-of-view (FOV) PET scanners using bismuth germanate (BGO) detectors without time-of-flight (TOF) capability are now available. These systems incorporate deep learning-based TOF (DLb-TOF) models to compensate for the absence of TOF. There is a lack of studies systematically investigating the optimal balance between signal to noise ratio and lesion detectability across a br
Background: Children in foster family care face elevated risks in mental and physical health, social functioning, and placement stability. Various interventions aim to strengthen foster family care, yet the evidence base remains unclear. Objective: This systematic review synthesizes evidence on the effects of interventions intended to strengthen foster family care on children’s well-being and func
Leaf chlorophyll (Chl) and carotenoids (Cxc) jointly govern light harvesting and photoprotection. However, concurrent retrieval from leaf reflectance remains challenging because Cxc absorption is weaker and strongly overlaps with Chl in the visible range. This spectral challenge, together with the physiological coordination between Chl and Cxc, motivates a multi-task learning (MTL) formulation for
Background. Seismocardiography (SCG) is a non-invasive, wearable technology that captures mechanical vibrations of the heart, offering a potential low-cost tool for assessing cardiac function. While conventional imaging modalities such as transthoracic echocardiography (TTE) and cardiac magnetic resonance (CMR) provide detailed structural and volumetric measures, they are operator-dependent and re
Perceived safety is a fundamental condition for people’s opportunity to move through and use urban public space. This thesis investigates how urban design can support perceived safety in everyday movement through public space, focusing on the area surrounding Persborg Train Station in Malmö. The project combines literature studies, document reviews, spatial mapping, and site observations to examin
Internationella investeringstvister skiljer sig från traditionella kommersiella skiljeförfaranden genom att statens samtycke till skiljeförfarande vanligtvis lämnas i förväg genom ett stående erbjudande i ett investeringsskyddsavtal. Ett bindande skiljeavtal mellan staten och den enskilda investeraren uppkom-mer först när en investerare som omfattas av erbjudandet accepterar detta, van-ligtvis genInternational investment disputes differ from traditional commercial arbitration proceedings in that the state’s consent to arbitration is usually given in ad-vance through a standing offer contained in an investment treaty. A binding arbitration agreement between the state and the individual investor arises only when an investor that falls within the scope of the offer accepts it, usually by init
Inom processrätten har det länge uttryckts att hypotetiska händelseförlopp är svåra att bevisa. I de nya rättsfallen NJA 2025 s. 1231 ”Konsignationsavtalet” och HD:s dom 2026–07–09 i mål nr T 8371-24 ”Innovationen” har domstolen dock uttalat att ett hypotetiskt händelseförlopp i sig inte utgör skäl för ett sänkt beviskrav. Hypotetiska händelseförlopp förekommer ofta i skadeståndsmål, såväl vid bedIt has long been acknowledged in procedural law that hypothetical sequences of events are difficult to prove. However, in the recent cases NJA 2025 p. 1231 ”Konsignationsavtalet” and the Swedish Supreme Court’s judgment of 09–07–2026, in case no. T 8371-24 ”Innovationen”, the court stated that a hypothetical sequence of events does not, in itself, constitute grounds for an alleviation of evidentia
Background: Several experimental studies have suggested potential anticarcinogenic effects of flavonoids, although epidemiologic evidence for the impact of dietary flavonoids on risk of gastric cancer (GC) is limited. Objective: We investigated the association between intake of dietary flavonoids and lignans and incident GC. Design: The study followed 477,312 subjects (29.8% men) aged 35-70 y from
