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Nordic consensus report on asthma management. Nordic Asthma Consensus Group

The work with the Nordic consensus report on asthma management started some years ago. The Nordic countries have common socioeconomic conditions. We acknowledge the international as well as other European guidelines providing valuable recommendations. Nevertheless, we felt the need to combine the common Nordic experiences in order to have a local statement of asthma and asthma care, based upon Nor

Characteristic odor of Osmoderma eremita identified as a male-released pheromone

Osmoderma eremita (Scopoli) is an endangered scarab beetle living in hollow trees. It has mainly been known for its characteristic odor, typically described as a fruity, peachlike or plumlike aroma. The odor emanating from a single beetle can sometimes be perceived from a distance of several meters. In this paper, we show that the characteristic odor from O. eremita is caused by the compound (R)-(

A Semi-Empirical Tire-Model for Transient Combined-Slip Forces

This paper presents a semi-empirical combined-slip tiremodel including transient behavior. The method relies on theassumption that the transient behavior is a result from the dynamicdeformation of the tire carcass and that the interaction between thelateral and longitudinal slip and forces can be explained by thedeformation of the rubber treads. The deformation of the tire carcassmakes the tread s

Applications of laser spectroscopy to analytical chemistry, environmental monitoring and medicine

Popular Abstract in Swedish Det ljus som vi vanligen ser, har spritts av objekten i vår omgivning. Ett annat ljusfenomen är fluorescens, som kan användas inom olika områden för analys av prover. Olika substanser ger skilda fluorescensprofiler. Om dessa inte helt överlappar varandra kan substanserna särskiljas. Områden, där ljusdiagnostik har använts inom ramen för detta arbete, är kemisk analys, mIn this thesis spectroscopic techniques have been used in the fields of analytical chemistry, environmental and medical applications. In analytical chemistry, laser induced fluorescence was used to image the separation of substances during capillary electrophoresis. Here, an optical fibre imaging technique facilitated a higher sensitivity compared with a lens imaging technique. The motion of the s

Diffuse large B-cell lymphoma - tumour characteristics on RNA and protein level associated with prognosis

Popular Abstract in Swedish Diffust storcelligt B-celllymfom (DLBCL) är den vanligaste aggressiva lymfomsjukdomen, och drabbar ca 450 personer årligen i Sverige. Med modern antracyklin-innehållande cytostatikabehandling är DLBCL en potentiellt botbar sjukdom. Av patienter med lokaliserad sjukdom botas 70 %, med spridd sjukdom ca 50 %. Bakgrunden till arbete 1 i denna avhandling var en rapport därDiffuse large B-cell lymphoma (DLBCL) is the most frequent lymphoma subtype. In Sweden 450 new cases are diagnosed annually. With modern anthracycline-containing chemotherapy DLBCL is potentially curable, with an estimated overall cure rate of approximately 50% for patients with advanced stage disease. Through molecular profiling of DLBCL the ?cell-of-origin concept? has been established: patients

Relationship between PTEN gene expression and differentiation of human glioma

Objective. To investigate the relationship between PTEN gene expression and differentiation of glioma. Material and methods. The quantitative real-time reverse transcription-polymerase chain reaction (RT-PCR) method was applied to detect PTEN mRNA levels in glioma tissues. Tumor-adjacent normal tissues and benign brain tumors were used as controls. Relative PTEN mRNA levels were determined as the

Lidocaine for treatment of severe seizures in newborn infants. II. Blood concentrations of lidocaine and metabolites during intravenous infusion

The blood concentrations of lidocaine and its main active metabolites, methylethylglycinexylidide (MEGX) and glycinexylidide (GX), were measured in 24 newborn infants during anticonvulsive treatment with an iv infusion of lidocaine. After a bolus dose of 1.5-2.2 mg/kg and continuous infusion of lidocaine (4.7-6.3 mg/kg/h) there was accumulation of the drug and MEGX within 24 h. After termination o

Degree of in vivo inhibition of human gastric and pancreatic lipases by Orlistat (Tetrahydrolipstatin, THL) in the stomach and small intestine.

BACKGROUND AND AIMS: Orlistat, a lipase inhibitor, strongly inhibits the activities of all gastric/pancreatic lipases except pancreatic phospholipase A(2)in vitro. In clinical use, for obesity treatment, it induces a variable degree of weight loss and steatorrhoéa. The aim of this study was to examine the degree of in vivo inhibition of individual gastric/pancreatic lipases by Orlistat in man, whe

The effect of exercise on the absorption of inhaled human insulin via the AERx insulin diabetes management system in people with type 1 diabetes

OBJECTIVE - This study investigated the effect of moderate exercise on the absorption of inhaled insulin via the AERx insulin diabetes management system (iDMS). RESEARCH DESIGN AND METHODS - in this randomized, open-label, four-period crossover, glucose clamp study 23 nonsmoking subjects with type I diabetes received a dose of 0.19 units/kg inhaled human insulin followed in random order by either