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Efficacy of asenapine in manic episodes with depressive symptoms: A review of post-hoc analyses
Background: Manic episodes with depressive symptoms represent a severe presentation of bipolar disorder. The effi-cacy of drugs shown useful for pure mania is largely unproven in the subset of patients with depressive symptoms. We reviewed different post-hoc analyses evaluating asenapine's effects in patients experiencing depressive symptoms during manic episodes. Methods: Different post-hoc analy
The impact study - Motivating a change in health behaviour
IMPaCT is a five-year project funded by the Department of Health, UK. Running in the UK and now Sweden, the IMPACT Project aims to target the poor physical health and excessive substance use seen in people with SMI. There is evidence that behavioural interventions may be associated with an improvement in physical health and substance use in this population. IMPaCT is a randomised controlled trial
The inadequacy of ADHD: a philosophical contribution
Attention Deficit Hyperactivity Disorder (ADHD) is a widely spread diagnosis.The dominant paradigm of ADHD is biomedical where ADHD isdefined as a brain disorder. At the same time, the legitimacy of thediagnosis is being questioned since it is unclear whether or not ADHDcan be deemed a medical disorder in itself. The aim of this article is tocritically assess the merits of understanding the diagnoAttention Deficit Hyperactivity Disorder (ADHD) is a widely spread diagnosis.The dominant paradigm of ADHD is biomedical where ADHD isdefined as a brain disorder. At the same time, the legitimacy of thediagnosis is being questioned since it is unclear whether or not ADHDcan be deemed a medical disorder in itself. The aim of this article is tocritically assess the merits of understanding the diagno
Social cognition, symptom profile, and quality of life in schizophrenia
Cats parallel great apes and corvids in motor self-regulation, but size matters
We tested domestic cats in the cylinder task, and found that they perform better ifthe cylinder is larger. We also found that their highest performance parallels that ofgreat apes and corvids, which are known as the best performing animals on this task.The cylinder task is used to test animals’ motor self-regulation. Recently a large-scalestudy tested 36 species on the task and found that absolute
Cylinder size affects cat performance in the motor self-regulation task
We tested domestic cats in the so-called cylinder task, and found that they perform better if the cylinder is larger. We also found that their highest performance parallels that of great apes and corvids, which are known as the best performing animals on this task. The cylinder task is used to test animals’ motor self-regulation: the inhibition of unproductive, but prepotent, movements in favour o
Techno-economic evaluation of biogas upgrading using ionic liquids in comparison with industrially used technology in Scandinavian anaerobic digestion plants
The process of biogas upgrading with ionic liquids, i.e. pure 1-butyl-3-methylimidazolium bis(trifluoro-methylsulfonyl)imide ([bmim][Tf2N]), aqueous choline chloride/urea (ChCl/Urea), and aqueous 1-allyl-3-methyl imidazole formate ([Amim][HCOO]), was simulated in Aspen Plus and compared with the conventional water scrubbing upgrading technique. The comparisons of the performances on the amount of
Do humans really prefer semi-open natural landscapes? A cross-cultural reappraisal
There is an assumption in current landscape preference theory of universal consensus in human preferences for moderate to high openness in a natural landscape. This premise is largely based on empirical studies of urban Western populations. Here we examine for the first time landscape preference across a number of geographically, ecologically and culturally diverse indigenous populations. Included
Pronouns in affinal avoidance registers : Evidence from the Aslian languages (Austroasiatic, Malay Peninsula)
Affinal avoidance registers are strategies of restrained linguistic conduct in relation to one’s in-laws. Current theories are primarily concerned with two types of strategies: (1) taboos on uttering the proper names of affines, and (2) substitution of everyday words with dedicated parallel lexicon in the presence of affines (so-called “mother-in-law languages”). However, the role of pronouns has
Being disconnected from life : meanings of existential loneliness as narrated by frail older people
Objectives: This study illuminated the meanings of existential loneliness (EL) as narrated by frail older people. Method: Data were collected through individual narrative interviews with 23 people 76–101 years old receiving long-term care and services. A phenomenological hermeneutical analysis was performed, including a naïve reading and two structural analyses as a basis for a comprehensive under
Improving patient-assessed outcomes after cataract surgery
Purpose: To identify and evaluate possible causes of poor patient-reported visual function after cataract surgery. Methods: We obtained retrospective data from the Swedish National Cataract Register on patient self-assessed visual function before and after cataract surgery based on the Catquest-9SF questionnaire. We identified patients who self-reported similar or more difficulties postoperatively
Long-term patient survival in a Swedish population-based cohort of patients with ANCA-associated vasculitis
Objectives: Patients with antineutrophil cytoplasmatic antibodies-associated vasculitides (AAV) exhibit higher mortality than the general population. In the current study, we assessed whether cluster affiliation based on clinical presentation might predict mortality. Methods: With case record review, the outcomes for a population-based cohort of patients diagnosed with AAV in southern Sweden (catc
Linking amyloid-β and tau deposition in Alzheimer disease
Loss of the tumor suppressor gene AIP mediates the browning of human brown fat tumors
Human brown fat tumors (hibernomas) display concomitant loss of the tumor suppressor genes MEN1 and AIP. In the present study, we hypothesized that the brown fat phenotype is attributed to these mutations. Accordingly, we demonstrate that silencing of AIP in human brown preadipocytic and white fat cell lines results in the induction of the brown fat marker UCP1. In human adipocytic tumors, loss of
The impact of clinical practice on the outcome of central venous access devices in children with haemophilia
Introduction: Central venous access devices facilitate home treatment in boys with haemophilia. These are usually fully implanted lines, referred to as ports. Caregivers are taught to manage the port using sterile techniques and maintaining patency by flushing with saline or heparin solution. National and international guidelines for the home care of ports are lacking. Aim: To evaluate if infectio
The Interrater Reliability of the Autism Diagnostic Interview-Revised (ADI-R) in Clinical Settings
Background: The Autism Diagnostic Interview-Revised (ADI-R) is considered a first choice assessment tool in autism spectrum disorder. Nevertheless, despite its wide use in psychiatric practice and recommendations by various clinical guidelines, its interrater reliability has predominantly been confirmed in research settings by specially trained, research reliability interviewers. The reliability o
Småstäder och andra orter i senmedeltidens Småland
Late medieval towns have often been neglected within the urban archaeological paradigm. This article tries to discuss the medieval urbanization from the perspective of small late medieval towns in relation to other types of central places by using a regional perspective. The towns of Vimmerby and Eksjö, and the central places of Värnamo and Vetlanda in Småland are used as examples. In this region,