Sökresultat

Filtyp

Din sökning på "*" gav 539937 sökträffar

How are thiopurines used and monitored by Swedish gastroenterologists when treating patients with inflammatory bowel disease?

Objective. To perform a survey of thiopurine treatment in inflammatory bowel disease (IBD) among Swedish gastroenterologists. Material and methods. A web-based questionnaire consisting of 25 multiple-choice questions was sent to 322 gastroenterologists in adult practice. Results. A total of 132 questionnaires were received giving a response rate of 41%. Thiopurines were used by all 122 gastroenter

Usefulness of Rajka and Langeland Eczema Severity Score in Clinical Practice.

Simple, validated eczema severity scores are required for the evaluation of interventions. The Rajka and Langeland (R and L) scale is based on 3 domains (extent, course, and intensity); however, its validity is not yet confirmed. The aim of this study was to investigate the quality aspects of the R and L scale in clinical practice. In the first part of the study, experts and consumers judged the c

Genome-wide transcription factor binding site/promoter databases for the analysis of gene sets and co-occurrence of transcription factor binding motifs.

BACKGROUND: The use of global gene expression profiling is a well established approach to understand biological processes. One of the major goals of these investigations is to identify sets of genes with similar expression patterns. Such gene signatures may be very informative and reveal new aspects of particular biological processes. A logical and systematic next step is to reduce the identified

A Novel Automated Platform for Quantifying the Extent of Skeletal Tumour Involvement in Prostate Cancer Patients Using the Bone Scan Index.

BACKGROUND: There is little consensus on a standard approach to analysing bone scan images. The Bone Scan Index (BSI) is predictive of survival in patients with progressive prostate cancer (PCa), but the popularity of this metric is hampered by the tedium of the manual calculation. OBJECTIVE: Develop a fully automated method of quantifying the BSI and determining the clinical value of automated

Face-to-Face, Buzz and Knowledge Bases: Socio-spatial implications for learning and innovation policy

While concurring with the new streams of literature in geography that highlight the importance of face-to-face and buzz in the globalizing learning economy, the article argues that this literature is misleading on three interrelated accounts. Firstly, it conflates face-to-face and buzz; secondly, it fails to distinguish between the importance of face-to-face and buzz for industries drawing on diff

No title

The Churches of Bornholm in the Early Middle Ages: The architecture of the 15 12th-13th C churches of the island is seen as an expression of a feudal society dominated by king and archbishop. The towers are interpreted as local symbols of the feudal lordship, and the vaulted upper storeys as treasuries where the revenues - grain, pork, butter and herring - were stored.

Deep sequencing of uveal melanoma identifies a recurrent mutation in PLCB4.

Next generation sequencing of uveal melanoma (UM) samples has identified a number of recurrent oncogenic or loss-of-function mutations in key driver genes including: GNAQ, GNA11, EIF1AX, SF3B1 and BAP1. To search for additional driver mutations in this tumor type we carried out whole-genome or whole-exome sequencing of 28 tumors or primary cell lines. These samples have a low mutation burden, with

EU-gruppundantag med förhinder

Artikel presenterar det nya förslaget till gruppundantag för tekniklicensavtal och granskar om kommissionen lyckas i sitt uppsåt att främja och förenkla tekniksamverkan i Europa. Dagens rättsläge diskuteras i avsnitt II. I avsnitt III presenteras det senaste förslaget översiktligt och därefter behandlas det nya marknadsandelsförslaget. I avsnitt V kommenteras hanteringen av marknadsuppdelning och