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Learning with Skill-based Robot Systems : Combining Planning & Knowledge Representation with Reinforcement Learning

The usage of robots in industry is transforming. Traditionally, robots have been deployed to automate monotonous tasks through manual programming, excelling in speed and precision yet lacking flexibility. Now, as part of Industry 4.0, the paradigm is shifting towards collaborative robotics, where robots are expected to interact dynamically with their environment and handle non-repetitive tasks. Th

The Meme’s-Eye View of Strategic Communication : A Case Study of Social Movements from a Memetic Perspective

The article argues that a memetic approach, or meme’s-eye view, could help bring together the strategic management view and the CCO-school. ‘Memes’ are understood as a second-order concept, i.e., as a reference to ‘memory traces’ in people’s minds and anchor-point of joint or collective intentionality. This view, it is argued, permits the conceptualization of communication as a resource. To illust

Beyond ambidexterity : universities and their changing roles in driving regional development in challenging times

Around the world today, universities are expected to play a unique role as creators of regional growth and innovation. While there appears to be a consensus that the role of universities has been expanded, critiques show that the contribution of universities to their regions is still not well defined. There have been some developments in the literature on the concept of modern universities such as

Exploitation of Engineered Light-Switchable Myosin XI for Nanotechnological Applications

For certain nanotechnological applications of the contractile proteins actin and myosin, e.g., in biosensing and network-based biocomputation, it would be desirable to temporarily switch on/off motile function in parts of nanostructured devices, e.g., for sorting or programming. Myosin XI motor constructs, engineered with a light-switchable domain for switching actin motility between high and low

Short and long-term associations between serum proteins linked to cardiovascular disease and particle exposure among constructions workers

Objectives Construction workers are exposed to respirable dust, including respirable crystalline silica (RCS), which is a potential risk factor for cardiovascular disease (CVD). The aim of this study was to evaluate whether exposure to particles among construction workers is associated with short-and long-term alterations in CVD-related serum proteins. Methods Using proximity extension assay, we m

Development and Validation of a Genomic Profile for the Omission of Local Adjuvant Radiation in Breast Cancer

PURPOSEAdjuvant radiotherapy (RT) is used for women with early-stage invasive breast cancer treated with breast-conserving surgery. However, some women with low risk of recurrence may safely be spared RT. This study aimed to identify these women using a molecular-based approach.METHODSWe analyzed two randomized trials of women with node-negative invasive breast cancer to ± RT following breast-cons

Reduced dose direct oral anticoagulants compared with warfarin with high time in therapeutic range in nonvalvular atrial fibrillation

Direct oral anticoagulants (DOACs) used in nonvalvular atrial fibrillation (NVAF) are dose-reduced in elderly and patients with impaired renal function. Only reduced dose dabigatran is concluded as having similar stroke risk reduction and lower risk of major bleeding than warfarin in the pivotal studies. In clinical practice, reduced dose is prescribed more often than expected making this an impor