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Because of the emergence of strains of Mycobacterium tuberculosis resistant to first-line antituberculosis agents, one of the second-line drugs, p-aminosalicylate (PAS), has regained importance in the treatment of tuberculosis. The mode of action of PAS, however, remains controversial as to whether it inhibits mycobactin or folate biosynthesis. To unravel this, we have studied the effect of PAS on

A »manly» Queen with »feminine» charm. Gender perspectives. Existential biography does not so much search for a logical development in a person’s life as for the opportunities to shape and choose between different paths. Instead of using identities, which are often ambiguous in the extreme, I follow the Swedish historian Henrik Rosengren in his use of different cultural identifications that toget

Background: In evaluating complex interventions, it is a challenge for researchers to provide transparent reporting of the intervention content with sufficient detail and clarity such that effects can be compared across studies or countries. Objective: To describe and compare the content of current rehabilitation for patients with inflammatory arthritis across 4 northern European countries. Patien

BACKGROUND AND PURPOSE: Distal radius fractures are most often treated nonoperatively, but sometimes they are treated surgically when deemed unstable. Based on the literature, a consensus protocol for treatment has been developed in southern Sweden to aid clinicians in their decision making. We evaluated the results of this protocol prospectively using a validated outcome instrument (DASH) in a la

Various neuropsychiatric disorders are a common feature of today. Not least the adhd diagnosis. The aim of the article is to provide an alternative model for understanding adhd which differ from the otherwise dominant neurobiological perspective. The method used was to let a person – Anders who is almost 30 years – tell about his life and his adhd diagnosis. Through the told story it becomes clear

Detailed stratigraphic analyses of sediments deposited in Lake Botjarnen, a small boreal forest lake in the shield terrain of central Sweden, clearly reflect progressively increasing human impact on terrestrial and aquatic ecosystems following settlement and establishment of an iron industry in the 17th century. Rising frequencies of pollen and spores from light-demanding plants provide evidence o

Two types of main-chain type polybenzoxazines with amide and benzoxazine groups as repeating units in the main chain, termed as poly(amide-benzoxazine), have been synthesized. They have been prepared by polycondensation reaction of primary amine-bifunctional benzoxazine with adipoyl and isophthaloyl dichloride using dimethylacetamide as solvent. Additionally, a model reaction is designed from the

Gas turbine blade tips encounter large heat load as they are exposed to the high temperature gas. A common way to cool the blade and its tip is to design a serpentine passage with 180-deg turns under the blade tip-cap inside the turbine blade. Improved internal convective cooling is therefore required to increase the blade tip lifetime. In this paper, turbulent fluid flow and heat transfer through

This thesis has contributed to the methodological development in the field of assistive technology and has generated new knowledge about the effectiveness and the service delivery process when powered mobility devices are provided to adult first time users in a Nordic context. Some of the results have been used to investigate the relationship between the three key elements of Donabedian’s conceptu

The competitions for the commission to decorate the Marriage Chamber in Stockholm City Law Courts (1912–1915) have become one of the most important events in the history of mural painting in Sweden. One of the proposals, by artist Isaac Grünewald, has become a major icon of early modernistic art in Sweden. Among the participants in the competition we find some of the most important introducers of

Making the built environment accessible for all regardless of functional capacity is an important goal for public health efforts. Considerable impediments to achieving this goal suggest the need for valid measurements of acccessibility and for greater attention to the complexity of person-environment fit issues. To address these needs, this study aimed to provide a methodological platform, useful

TLR agonists are attractive candidate adjuvants for therapeutic cancer vaccines as they can induce a balanced humoral and T cell-mediated immune response. With a dense network of dendritic cells (DCs) and draining lymphatics, the skin provides an ideal portal for vaccine delivery. Beside direct DC activation, TLR agonists may also induce DC activation through triggering the release of inflammatory

In the study of insect neuroanatomy, three-dimensional (3D) reconstructions of neurons and neuropils have become a standard technique. As images have to be obtained from whole-mount brain preparations, pigmentation on the brain surface poses a serious challenge to imaging. In insects, this is a major problematic in the first visual neuropil of the optic lobe, the lamina, which is obstructed by the

Host defense peptides have recently gained much interest as novel anti-infectives owing to their ability to kill bacteria and simultaneously modulate host cell responses. The cationic host defense peptide GKY25 (GKYGFYTHVFRLKKWIQKVIDQFGE), derived from the C terminus of human thrombin, inhibits proinflammatory responses in vitro and in vivo, but the mode of action is unclear. In this study, we sho

The kinking of a corrosion crack due to mixed-mode fatigue loading is studied using an adaptive finite element procedure. The rate of material dissolution is assumed to be proportional to the stretching of the corroding surface. The dissolution of material is governed by a corrosion law, where no criterion is needed for neither crack growth nor growth direction. The problem is treated as a general

Hemoglobin is the major oxygen-carrying system of the blood, but has many potentially dangerous side effects due to oxidation and reduction reactions of the heme-bound iron and oxygen. Extracellular hemoglobin, resulting from hemolysis or exogenous infusion, is shown to be an important pathogenic factor in a growing number of diseases. This review briefly outlines the oxidative/reductive toxic rea

The experimental detector setup TASISpec (TA SCA in Small Image mode Spectroscopy) comprises composite Ge- and highly segmented Si-detectors. The setup is constructed to provide multi-coincidence spectroscopic data between gamma-rays, X-rays, conversion electrons, fission fragments, and alpha-particles for heavy and superheavy elements (Z >= 100). The full array has been virtually constructed usin

Popular Abstract in Swedish När elektroner som färdas i en hastighet nära ljusets hastighet böjs av i ett magnetfält genereras framåtriktad elektromagnetisk strålning. Denna strålning, som även kallas synkrotronljus, kan användas för att studera strukturer och egenskaper hos olika material. Vid en synkrotronljuskälla, som t.ex. MAX II eller MAX III vid MAX-lab i Lund, cirkulerar elektroner runt i The MAX II and MAX III synchrotron light sources at MAX-lab provide synchrotron radiation for experiments in a wide variety of research fields. The synchrotron radiation is emitted by ultra-relativistic electrons circulating in electron storage rings. In this thesis the transverse and longitudinal electron beam sizes and the electron beam lifetime limitations in electron storage rings are discusse

I denna studie diskuterar vi en av flera intressanta aspekter, som verkar göra nätburen utbildning klart positivare än campusutbildning, nämligen faktumet att lärare och studenter kommer närmare varandra på Internet-baserade kurser än på campuskurser.