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Glycaemic control, disease duration and beta-cell function in patients with Type 2 diabetes in a Swedish community. Skaraborg Hypertension and Diabetes Project.

AimsTo examine determinants for glycaemic control in primary care patients with Type 2 diabetes. MethodsIn a community-based surveillance of primary care patients with Type 2 diabetes, 190 men and 186 women were consecutively identified and examined for cardiovascular risk factors. Insulin resistance and beta-cell function were estimated using homeostasis model assessment (HOMA). Good glycaemic c

Gender equality in the work of local research ethics committees in Europe: a study of practice in five countries

Background: Funding organisations and research ethics committees (RECs) should play a part in strengthening attention to gender equality in clinical research. In the research policy of European Union (EU), funding measures have been taken to realise this, but such measures are lacking in the EU policy regarding RECs. Objective: To explore how RECs in Austria, Germany, Ireland, The Netherlands and

Evaluation of a pre-cell hit detector for the future single ion hit facility in Lund

Currently, a single ion hit facility, for irradiation of single cells with single, light MeV ions is under development at the Lund Nuclear Microprobe. In this paper, a novel approach to the ion detection issue is presented. A silicon detector, a type utilized at other facilities for post-cell ion detection, has been investigated as a possible option for pre-cell hit detection. If proven successful

Fuktdimensionering ger fuktsäkrare byggnader (informationsskrift i serien: Fuktsäkerhet i byggnader)

Bygg rätt från början är ett centralt motto om man vill bygga ett sunt hus. Fuktdimensionering är en hjälp för att lyckas med detta. Fukt orsakar ofta dålig innemiljö och kostnaden för att åtgärda fuktskador uppgår till miljardbelopp årligen. Genom att använda den kunskap som finns skulle de vanligaste fuktproblemen kunna undvikas. Kunskapen finns dokumenterad bl a i serien Fuktsäkerhet i byggnade

Epicardial and endocardial dispersion of ventricular repolarization. A study of monophasic action potential mapping in healthy pigs.

Objectives. To investigate the total dispersion of ventricular repolarization of the epi- and endocardium. Design. Monophasic action potentials (MAP) were recorded from 211 +/- 54 (151-353) left and right ventricular epi- and endocardial sites during atrial pacing in 10 pigs using the CARTO system. The activation time (AT), MAP duration (MAPd) and end of repolarization time (EOR) were measured. Re

Silicon neural interfaces -Design and biomedical aspects-

This thesis covers the development of a silicon neural interface, with focus on silicon sieve electrode fabrication, design, nerve regeneration, signal recording and biocompatibility. A study of how the via hole size and transparency of the perforated sieve membrane influences the nerve regeneration is presented together with a study on soft tissue responses to planar and porous silicon. A method

Direct cytoplasmic CA(2+) responses to gastrin-releasing peptide in single beta cells

The neuropeptide gastrin releasing peptide (GRP) stimulates insulin secretion and induces oscillations of the cytoplasmic Ca(2+) concentration ([Ca(2+)](cyt)) in clonal insulinoma cells. It is not known whether GRP affects [Ca(2+)](cyt) in normal beta cells. We investigated, in single, normal, mouse islet beta cells, the effects of GRP on [Ca(2+)](cyt), by dual wavelength spectrophotofluorometry.

On Dynamic Real-Time Scheduling of Model Predictive Controllers

The paper discusses dynamic real-time scheduling in the context ofmodel predictive control (MPC). Dynamic scheduling in this settingis motivated by the highly varying execution times associated withMPC controllers. Premature termination of the optimization algorithmis exploited to trade off prolonged computations versuscomputational delay. A feedback scheduling strategy for multiple MPCcontrollers

Effects of organic solvents on motor activity in mice

Groups of male mice were exposed via inhalation to methylene chloride, perchloroethylene, toluene, trichloroethylene or 1,1,1-trichloroethane. The exposures were started at 2300 h. Generation of vapor was stopped after 1 h. Motor activity of the animals during the exposures was measured with a Doppler radar. Several concentrations of each solvent were tested. Concentrations could be found for all

Assessments of PSA Forms and hK2 as Very Early Predictors of Prostate Cancer

Popular Abstract in Swedish Prostatacancer är den bland män vanligast förekommande cancerformen i Sverige. Under 2003 diagnostiserades 9882 nya fall. Sjukdomen drabbar framför allt äldre individer; många män är 70 år gamla eller äldre när de får diagnosen. Sjukdomsförloppet kan vara mycket varierande. Hos många är tumörtillväxten långsam, men sjukdomen kan också utvecklas snabbt. Många patienter lConcentrations of prostate-specific antigen (PSA) and human kallikrein 2 (hK2) were investigated in blood samples that had been obtained from men who were diagnosed with prostate cancer (PCa) decades later. The studies were based on a cohort comprising 22,444 men who, in 1974?1986, were early middle aged and represented a non-PCa-screened population. The results clearly demonstrate a very strong c