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Introduction: The ε4 allele of the apolipoprotein E (APOE) gene is a prominent risk factor for Alzheimer's disease (AD), but its implication in other dementias is less well studied. Methods: We used a data set on 2858 subjects (1098 AD, 260 vascular dementia [VaD], 145 mixed AD and VaD, 90 other dementia diagnoses, and 1265 controls) to examine the association of APOE polymorphisms with clinical d

In order to meet the requirements in the stringent emission regulations, more and more research work has been focused on homogeneous charge compression ignition (HCCI) and partially premixed combustion (PPC) or partially premixed compression ignition (PCCI) as they have the potential to produce low NOx and soot emissions without adverse effects on engine efficiency. The mixture formation and charg

Small closely-coupled post injections of fuel in diesel engines are known to reduce engine-out soot emissions, but the relative roles of various underlying in-cylinder mechanisms have not been established. Furthermore, the efficacy of soot reduction is not universal, and depends in unclear ways on operating conditions and injection schedule, among other factors. Consequently, designing engine hard

Background: Pain from various locations in the body and mental illness are common and the comorbidity between the two is well-known although the temporal relationship remains to be determined. Our aim was to follow patients over time to study if pain (here dorsalgia/abdominal pain) or fibromyalgia lead to an increased risk of developing mental illness (here depression/anxiety) and/or the reverse,

Although predation is commonly thought to exert the strongest selective pressure on coloration in aposematic species, sexual selection may also influence coloration. Specifically, polymorphism in aposematic species cannot be explained by natural selection alone. Males of the aposematic wood tiger moth (Arctia plantaginis) are polymorphic for hindwing coloration throughout most of their range. In S

We present a dual-wavelength polarimetric measurement method to distinguish species and sexes of disease transmitting mosquitoes in flight. By measuring co- and de-polarized backscattered light at 808 and 1550nm, the degree of linear polarization, wingbeat frequency, reflectance, spectral ratio and glossiness of mosquitoes can be retrieved. Body and wing contributions to these signals can be separ

This thesis is concerned with refugee status determination (RSD) in the context of ‘natural’ disasters and climate change. Considering evidence that the legal predicament of people who seek recognition of refugee status in this connection has been inconsistently addressed by judicial bodies in leading refugee law jurisdictions, and identifying theoretical as well as doctrinal impediments to a cleaThis thesis is concerned with refugee status determination (RSD) in the context of ‘natural’ disasters and climate change. Considering evidence that the legal predicament of people who seek recognition of refugee status in this connection has been inconsistently addressed by judicial bodies in leading refugee law jurisdictions, and identifying theoretical as well as doctrinal impediments to a clea

This paper reports on a rare case study of Australian university extension in rural tourism enterprise development. The case primarily draws on a review of 89 participant evaluation surveys, supplemented by document review and program manager interview. Findings highlight the importance of program adaptation to client needs, noting particular benefits of personal delivery methods, especially works

The influence of the ignition quality of diesel-and gasoline-like fuels on the lift-off length of the jet were investigated in an optical heavy duty engine. The engine was operated at a load of 22 bar IMEPg and 1200 rpm. A production type injector with standard holes were used. The lift-off length was recorded with high speed video Different injection pressures and inlet temperatures were used to

Impaired incretin effect is a culprit in Type 2 Diabetes. Cocaine- and amphetamine-regulated transcript (CART) is a regulatory peptide controlling pancreatic islet hormone secretion and beta-cell survival. Here we studied the potential expression of CART in enteroendocrine cells and examined the role of CART as a regulator of incretin secretion and expression. CART expression was found in glucose-

Diesel engines are one of the most important power generating units these days. Increasing greenhouse gas emissions level and the need for energy security has prompted increasing research into alternative fuels for diesel engines. Biodiesel is the most popular amongst the alternatives for diesel fuel as it is biodegradable, renewable and can be produced domestically from vegetable oils. In recent

Purpose: Manufacturer specifications for the resolution of an additive manufacturing (AM) machine can be ten times smaller (more optimistic) than the actual size of manufacturable features. Existing methods used to establish a manufacturable design rule-set are conservative piecewise-constant approximations. This paper aims to evaluate the effectiveness of a first-order model for producing improve

The concept of myth is far from foreign to geographical research, yet its definition and use has been both varied and assumed, leaving much of its potential geographically unexplored. Myths – naturalised stories which reflect ideology, alleviate anxiety, and guide everyday practices – instil place with meaning. Following the tradition within human geography of engaging with issues intersecting per

Metformin is eliminated through glomerular filtration and tubular secretion in the kidneys. New guidelines recommend use of metformin down to a GFR of 30 mL/min under the condition that the dose is adjusted. As the risk of inducing lactic acidosis is very low in connection with administration of iodine contrast media, new recommendations in Sweden say that metformin must be stopped only when GFR iTreatment with metformin in type 2 diabetes mellitus-new routines when renal function is reduced and in connection with administration of iodine contrast media Metformin is eliminated through glomerular filtration and tubular secretion in the kidneys. New guidelines recommend use of metformin down to a GFR of 30 mL/min under the condition that the dose is adjusted. As the risk of inducing lactic a

Aim: To add to our knowledge concerning the key elements involved in the individual’s experience of growing up with substance abusing parents and the resulting challenges this involved for their own parenthood. Methods: In-depth interviews were conducted with 19 parents who had participated in a mental health intervention programme. All had experienced substance abusing parents in their family of

Collaborative networks provide a viable means for destination management organisations (DMOs) to engage small enterprises in collaborative destination development, and may offer a means to steer destinations toward small enterprises in collaborative destination development, and may offer a means to steer destinations toward sustainability. However, the use of collaborative networks in destination

The book took as its starting point the distinction practised by Roland Barthes between texts of pleasure and texts of jouissance. All the chapters in the book are a commentarius perpetuus at the century-long querelle des anciens et des modernes, the purpose being the aesthetic criteria in establishing the chronotope of masterpiece.

Despite the growing interest for visualization of sentiments and emotions in textual data, the task of detecting and visualizing various stances is not addressed well by the existing approaches. The challenges associated with this task include development of the underlying computational methods and visualization of the corresponding multi-label stance classification results. In this poster abstrac