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We could determine the S-phase fraction (SPF) by flow cytometric DNA analysis of paraffin archival material in 160 of 260 patients with soft-tissue sarcoma of extremity and trunk wall. The prognostic value of SPF was compared with other clinicopathological factors. The median follow-up time was 16 (6-31) years. In a univariate analysis, deep tumour location, increasing tumour size and histological

The morphologic and physiologic effects of vitamin E, a powerful antioxidant, on the autolysis and sporulation of Aspergillus nidulans FGSC26 were studied. In carbon-depleted submerged cultures, reactive oxygen species (ROS) accumulated in the cells and, concomitantly, progressing autolysis was observed, which was characterized by decreasing dry cell masses and pellet diameters as well as by incre

One of the central questions in theoretical particle physics, since already several decades, has been that of "masses and mixings of the quarks. With the entry of neutrino oscillations into the field, the issue of lepton masses has added a new dimension to the problem. In the literature one finds many models of quark and lepton mass matrices. However, the mass and mixing problems remain unsolved.

Late Weichselian and early Holocene partly carbonate-rich sediments from a small lacustrine deposit in Skane, southern Sweden, were analysed for stable carbon and oxygen isotopes and mollusc assemblages. The data from these analyses reveal a pronounced climatic warming at c. 12,400 BP, accompanied by a general change from continental to maritime conditions. Two significant climatic oscillations we

Accommodative pupil constrictions were compared between 27 children (9-10years) and 13 young adults (22-26years) in order to clarify the issue whether or not children have such a response. Accommodative stimuli of 4 and 7 diopters were used to elicit the response and experiments were performed at 5 and 100lux in order to investigate whether the level of ambient light has different effects on devel

We present a method for studying large finite periodic structures using software developed for infinite periodic structures. The method is based on the Floquet-Bloch transformation, which splits the spatial description into one microscopic spatial variable inside the unit cell, and one macroscopic wave vector describing the variations on a scale encompassing many unit cells. The resulting algorith

A dry release method for fabrication of suspended nanostructures is presented. The technique has been combined with an anti-stiction treatment for fabrication of nanocantilever based nanoelectromechanical systems (NEMS). The process combines a dry release method, using a supporting layer of photoresist which is removed using oxygen ashing in a reactive ion etcher (RIE), with CHF3 plasma induced de

Background: The purpose of this study was to investigate whether different behaviors in a stressful situation modify the risk of atherosclerosis in association with a myocardial infarction, cardiovascular mortality, and all-cause mortality. Many individuals have atherosclerotic changes in their arteries but may never experience any symptoms nor develop cardiovascular disease. A myocardial infarcti

Background: It has recently been reported that sulindac has an apoptotic effect on KYN-2 cells, an undifferentiated hepatoma cell line. The present work investigates whether sulindac also has an apoptotic effect on well-differentiated hepatoma cells and what its potential mechanism might be. Materials and Methods: Hep G2 cells were treated with sulindac at different concentrations. Apoptosis rate,

While implementing the EC Procurement Directives in Swedish legislation, there remains a reference to 'business-like' (affärsmässig) practice as an external system of norms. The problem is that the term a. might contradict non-economic considerations in the award of contracts. Municipal procurement is often managed by professionals with limited legal expertise, and diverging practices are found. I

Sera from patients with sexually acquired reactive arthritis (SARA) with antibodies reacting with C. trachomatis and C. pneumoniae (group 1; n = 20) and also with C. psittaci (group 2; n = 19) were analyzed for antibody specificity. Sera from group 2 reacted significantly more often with C. trachomatis serotype E, H and K and had higher antibody titers to serotype E, as tested by microimmunofluore

Compared with Hipparcos, Gaia will give an enormous improvement in accuracy, completeness and number of stars: about two orders of magnitude in accuracy, four orders in number, and a completeness limit that is 12 magnitudes fainter. How is all this possible? The answer is: by a combination of many factors, the most important being bigger and more efficient detectors, and bigger optics. The method

Satellite telemetry was used to record the submergence duration of green turtles (Chelonia mydas) as they migrated from Ascension Island to Brazil (N=12 individuals) while time/depth recorders (TDRs) were used to examine the depth distribution and dive profiles of individuals returning to Ascension Island to nest after experimental displacement (N=5 individuals). Satellite telemetry revealed that