Magnesium, the second and fourth most abundant cation in the intracellular compartment and whole body, respectively, is of great physiologic importance. Magnesium exists as bound and free ionized forms depending on temperature, pH, ionic strength, and competing ions. Free magnesium participates in many biochemical processes and is most commonly measured by ion-selective electrode. This analytical

A likelihood-based discriminant for the identification of quark- and gluon-initiated jets is built and validated using 4.7 fb of proton-proton collision data at collected with the ATLAS detector at the LHC. Data samples with enriched quark or gluon content are used in the construction and validation of templates of jet properties that are the input to the likelihood-based discriminant. The discrim

South Africa is a complex and dynamic society, with overwhelming and increasing problems with disaster risk in the vulnerable urban communities in and around its rapidly growing metropolitan centres. The purpose of this study is to improve the understanding of the challenges for disaster risk reduction in such communities. It focuses on the case of Imizamo Yethu, in the Western Cape, in order to b

The Brain-Expressed X-linked (BEX) family proteins are comprised of five human proteins including BEX1, BEX2, BEX3, BEX4 and BEX5. BEX family proteins are expressed in a wide range of tissues and are known to play a role in neuronal development. Recent studies suggest a role of BEX family proteins in cancers. BEX1 expression is lost in a subgroup of patients with acute myeloid leukemia (AML) and c

Long-term mallard capture-recapture data from Sweden and Finland were analyzed to describe temporal mortality patterns and reasons. We used program MARK and Seber models to estimate annual survival (S) and recovery (r) rates. Survival rates were used in a Monte Carlo simulation to evaluate the correspondence between observed and predicted annual population sizes of a Finnish sub-population. About

The growth of epitaxial graphene on SiC has been identified as one of the most promising techniques to produce graphene for electronic applications. In this paper, we present a systematic study of the electronic and structural properties of large-area quasifree standing epitaxial monolayer graphene grown on top of the SiC(0001) surface. For this purpose, we combine the thermal treatment of SiC in

Purpose: We determined if the deliberate establishment of asymptomatic bacteriuria with Escherichia coli 83972 in patients with incomplete bladder emptying and recurrent urinary tract infection protects against recurrence. Materials and Methods: In phase 1 of the study the patients were randomized to blinded inoculations with E. coli 83972 or saline. Crossover occurred after monitoring for 12 mont

Hairdressing work is classified as carcinogenic based on excess risk for bladder cancer. We aimed at evaluating if current hairdressers are exposed to established/suspected bladder carcinogens (aromatic amines) and indicate possible sources of exposure.

The satellite-derived normalized difference vegetation index (NDVI), which is used for estimating gross primary production (GPP), often includes contributions from both mosses and vascular plants in boreal ecosystems. For the same NDVI, moss can generate only about one-third of the GPP that vascular plants can because of its much lower photosynthetic capacity. Here, based on eddy covariance measur

Tyler, G. 2010: Variability in colour, metallic lustre, and body size of Carabus arvensis Herbst, 1784 (Coleoptera: Carabidae) in relation to habitat properties.-Entomol. Fennica 21: 90-96. Objectives are to elucidate whether populations of Carabus arvensis Herbst, 1784 from contrasting habitats differ in (i) colour, (ii) brightness of metal lustre, or (iii) body size (length of elytra, of elytra

Popular Abstract in Swedish HIV består av två besläktade virusvarianter, HIV-1 och HIV-2. Båda kan orsaka uttalad immunbrist (AIDS) hos drabbade individer, men detta sker långsammare vid HIV-2. HIV-1 är viruset som orsakat den globala HIV epidemin medan HIV-2 främst hittas i Västafrika. HIV infekterar kroppens immunceller genom att binda till vissa äggviteämnen på cellytan. Efter inbindning till CHIV-1 infection of CD4+ immune cells requires the assistance of cellular coreceptors. The regulation of these receptors is highly dynamic. In addition to the major coreceptors, CCR5 and CXCR4, several alternative coreceptors mediate entry for selected HIV isolates in vitro, although their role in vivo is yet to be established. Compartmentalized HIV-1 infection of the central nervous system (CNS) m

Interference among predators decreases per capita foraging rates and has implications for both community dynamics and top-down trophic processes. Interference originates from behavioural interactions among foragers, and these behaviours could be affected by environmental conditions. In experiments on pike foraging alone or among conspecifics in different levels of water turbidity, we expected high

Heparan sulfate (HS), a substance common in the extracellular matrix on epithelial cells is present in the pancreas, lining the duct lumen. During pathological conditions, we propose that it can be shed from the ECM and bind to receptors on the cell surface, thus triggering an inflammatory response, which if excessive can cause acute pancreatitis (AP). Infusion of HS in the pancreatic duct in rats

This study explores the differences in oral narrative skills between school-age children with mild-to-moderate sensorineural hearing loss (HL) and children who have typical hearing and language development. Narrative samples were collected following a picture-elicited storytelling task. Language samples were transcribed and coded for a number of measures, including narrative content, syntax, and g

With aging, the incidence of falls and fractures increases. There has during the last decades been secular changes in demographics so that the proportion of elderly increases in society. Hence, there is an increasing need for clinicians to be able to make a solid appraisal of the elderly patient's functional capacity, as to identify individuals with an increased risk to fall. If high risk individu

1. Permutation tests are important in ecology and evolution as they enable robust analysis of small sample sizes and control for various forms of dependencies among observations. A common source of dependence is spatial autocorrelation. Accounting for spatial autocorrelation is often crucial, because many ecological and evolutionary processes are spatially restricted, such as gene flow, dispersal,

Tasquinimod is an orally active antiangiogenic drug that is currently in phase III clinical trials for the treatment of castration-resistant prostate cancer. However, the target of this drug has remained unclear. In this study, we applied diverse strategies to identify the histone deacetylase HDAC4 as a target for the antiangiogenic activity of tasquinimod. Our comprehensive analysis revealed allo