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Transfer into L3 English : Global accent in German-dominant heritage speakers of Turkish

This study is concerned with L3 acquisition in heritage speakers (HSs). The goals are to incorporate HSs into L3 acquisition research and investigate the role of language dominance for predicting L3 transfer. We analyze global accent in German-Turkish early bilinguals, HSs of Turkish, who acquired English as their L3. Twenty native-speaker judges determined accent strength and accent source in the

Enzymatic Activity of Lipase-Nanoparticle Conjugates and the Digestion of Lipid Liquid Crystalline Assemblies

Variants of lipase were attached to gold nanoparticles (NPs) and their enzymatic activity was studied. The two bioengineered lipase variants have been prepared with biotin groups attached to different residues on the protein outer surface. The biotinylation was evidenced by denaturing polyacrylamide gel electrophoresis and quantified by the ([2-(4'-hydroxyazobenzene)]benzoic acid spectrophotometri

The influence of crystalline lens accommodation on post-saccadic oscillations in pupil-based eye trackers

It is well known that the crystalline lens (henceforth lens) can oscillate (or 'wobble') relative to the eyeball at the end of saccades. Recent research has proposed that such wobbling of the lens is a source of post-saccadic oscillations (PSOs) seen in data recorded by eye trackers that estimate gaze direction from the location of the pupil. Since the size of the lens wobbles increases with accom

Atomic Scale Surface Structure and Morphology of InAs Nanowire Crystal Superlattices: The Effect of Epitaxial Overgrowth

While shell growth engineering to the atomic scale is important for tailoring semiconductor nanowires with superior properties, a precise knowledge of-the surface structure and morphology at different stages of this type of overgrowth has been lacking. We present a systematic scanning tunneling microscopy (STM) study of homoepitaxial Shell growth of twinned superlattices in zinc blende InAs nanowi

Membrane Interaction of α-Synuclein in Different Aggregation States

Aggregated α-synuclein in Lewy bodies is one of the hallmarks of Parkinson's disease (PD). Earlier observations of α-synuclein aggregates in neurons grafted into brains of PD patients suggested cell-to-cell transfer of α-synuclein and a prion-like mechanism. This prompted the current investigation of whether α-synuclein passes over model phospholipid bilayers. We generated giant unilamellar vesicl

Drawing Planar Graphs on Points Inside a Polygon

In this paper, we study the problem of drawing a given planar graph such that vertices are at pre-specified points and the entire drawing is inside a given polygon. We give a method that shows that for an $n$-vertex graph and a $k$-sided polygon, $\Theta(kn^2)$ bends are always sufficient. We also give an example of a graph where $\Theta(kn^2)$ bends is necessary for such a drawing.

Peer Deviance, Parental Divorce, and Genetic Risk in the Prediction of Drug Abuse in a Nationwide Swedish Sample: Evidence of Environment-Environment and Gene-Environment Interaction.

IMPORTANCE Peer deviance (PD) strongly predicts externalizing psychopathologic conditions but has not been previously assessable in population cohorts. We sought to develop such an index of PD and to clarify its effects on risk of drug abuse (DA). OBJECTIVES To examine how strongly PD increases the risk of DA and whether this community-level liability indicator interacts with key DA risk factors a

"Young Women": The Meaning of a Collaborative Program Supporting Young Women's Rehabilitation and Reintegration into the Labor Market.

Women are at a higher risk for long-term sick leaves and mental ill health. The aim of this study was to explore a supportive program's meaning for women with anxiety/stress/depression problems that are unemployed and/or on a sick leave, and for the personnel involved. Seven women and the personnel (n = 5) were interviewed individually pre- and post-intervention. Data was analyzed using content an

Visualization and phenotyping of proinflammatory antigen-specific T cells during collagen-induced arthritis in a mouse with a fixed collagen type II-specific transgenic T-cell receptor beta-chain

Introduction: The V beta 12-transgenic mouse was previously generated to investigate the role of antigen-specific T cells in collagen-induced arthritis (CIA), an animal model for rheumatoid arthritis. This mouse expresses a transgenic collagen type II (CII)-specific T-cell receptor (TCR) beta-chain and consequently displays an increased immunity to CII and increased susceptibility to CIA. However,

A Charter Moment: Restructuring Governance for Sustainability

We are living in a highly dynamic, human-dominated Earth System in which non-linear, abrupt and irreversible changes are not only possible but also probable. These changes require institutional structures capable of steering human society away from critical tipping points and irreversible change and ensuring sustainable livelihoods for all. We see 2012 as a charter moment, a historic opportunity t

Mutation spectrum in South American Lynch syndrome families

Background: Genetic counselling and testing for Lynch syndrome have recently been introduced in several South American countries, though yet not available in the public health care system. Methods: We compiled data from publications and hereditary cancer registries to characterize the Lynch syndrome mutation spectrum in South America. In total, data from 267 families that fulfilled the Amsterdam c

Age at first introduction to complementary foods is associated with sociodemographic factors in children with increased genetic risk of developing type 1 diabetes.

Infant's age at introduction to certain complementary foods (CF) has in previous studies been associated with islet autoimmunity, which is an early marker for type 1 diabetes (T1D). Various maternal sociodemographic factors have been found to be associated with early introduction to CF. The aims of this study were to describe early infant feeding and identify sociodemographic factors associated wi

Finite volume for three-flavour Partially Quenched Chiral Perturbation Theory through NNLO in the meson sector

We present a calculation of the finite volume corrections to meson masses and decay constants in three flavour Partially Quenched Chiral Perturbation Theory ( PQChPT) through two-loop order in the chiral expansion for the flavour-charged ( or off-diagonal) pseudoscalar mesons. The analytical results are obtained for three sea quark flavours with one, two or three different masses. We reproduce the

Recovery after total intravenous general anaesthesia or spinal anaesthesia for total knee arthroplasty: a randomized trial.

BACKGROUND: /st>This study was undertaken to compare the effects of general anaesthesia (GA) and spinal anaesthesia (SA) on the need for postoperative hospitalization and early postoperative comfort in patients undergoing fast-track total knee arthroplasty (TKA). METHODS: /st>One hundred and twenty subjects were randomly allocated to receive either intrathecal bupivacaine (SA group) or GA with tar

Sympatric divergence and clinal variation in multiple coloration traits of Ficedula flycatchers

Geographic variation in phenotypes plays a key role in fundamental evolutionary processes such as local adaptation, population differentiation and speciation, but the selective forces behind it are rarely known. We found support for the hypothesis that geographic variation in plumage traits of the pied flycatcher Ficedula hypoleuca is explained by character displacement with the collared flycatche

β-cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment.

Objective: This report examines the foundation of β-cell failure in type 2 diabetes and suggests areas for future research on the underlying mechanisms that may lead to improved prevention and treatment. Participants: A group of experts participated in a conference on October 14-16, 2013 cosponsored by The Endocrine Society and the American Diabetes Association. A writing group prepared this summa

Educational achievements in Pierre Robin Sequence

The aim of this retrospective population-based study was to determine if there is any significant difference in academic achievement between students with a Pierre Robin Sequence (PRS) compared with the general population of Swedish students at the typical time of graduation from compulsory school (usually at 16 years of age). The data were obtained from the Swedish Medical Birth Register for the

Spatio-temporal skin strain distributions evoke low variability spike responses in cuneate neurons

A common method to explore the somatosensory function of the brain is to relate skin stimuli to neurophysiological recordings. However, interaction with the skin involves complex mechanical effects. Variability in mechanically induced spike responses is likely to be due in part to mechanical variability of the transformation of stimuli into spiking patterns in the primary sensors located in the sk