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Prevalence of Severe Visual Disability Among Preterm Children With Retinopathy of Prematurity and Association With Adherence to Best Practice Guidelines

Importance: Retinopathy of prematurity (ROP) can cause severe visual disability even in high-resource settings. A better understanding of the prevalence and processes leading to ROP-induced severe visual impairment may help health care professionals design preventive measures.Objectives: To determine the prevalence of severe visual disability among children born preterm in Sweden, evaluate adheren

Human Rights

Halme-Tuomisaari has written the definitions for keywords ‘Human Rights’, ‘International Humanitarian Law’ & ‘Monitoring Mechanisms’

Guarding utopia : Law, vulnerability and frustration at the UN Human Rights Committee

In the 1940s activists lobbied for the creation of a binding international bill of rights backed up by an international human rights court as the backbone of the post‐World War II order. Together, so the activists believed, these would guarantee peace and harmony to all mankind. Seven decades later this vision has been transformed into a cluster of UN human rights treaties and expert committees kn

Targeting OGG1 arrests cancer cell proliferation by inducing replication stress

Altered oncogene expression in cancer cells causes loss of redox homeostasis resulting in oxidative DNA damage, e.g. 8-oxoguanine (8-oxoG), repaired by base excision repair (BER). PARP1 coordinates BER and relies on the upstream 8-oxoguanine-DNA glycosylase (OGG1) to recognise and excise 8-oxoG. Here we hypothesize that OGG1 may represent an attractive target to exploit reactive oxygen species (RO

Where’s the well : DNA evidence, personal narratives and unpredictability in Finnish family reunification

For people on the move, family reunification has become a major ‘channel’ to Europe and the ‘right to family’ is a widely recognized principle in international human rightsprotection and domestic legislations. Yet in practice exercising this ‘right’ is oftendifficult and migration buraucracies leave applicants unsure not only of the outcomeof their applications but of the criteria that are relied