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Identification of cardiomyocyte nuclei has been challenging in tissue sections as most strategies rely only on cytoplasmic marker proteins(1). Rare events in cardiac myocytes such as proliferation and apoptosis require an accurate identification of cardiac myocyte nuclei to analyze cellular renewal in homeostasis and in pathological conditions(2). Here, we provide a method to isolate cardiomyocyte
Huntington's disease (HD) is an inherited neurodegenerative disorder characterized by both neurological and systemic abnormalities. Immune activation is a well-established feature of the HD brain and we have previously demonstrated a widespread, progressive innate immune response detectable in plasma throughout the course of HD. In the present work we used multiplex ELISA to quantify levels of che
Dendrochronology and source-criticism - on the dating of the Romanesque rebuilding of the church in Stora Köpinge: The dendro-dating of a "Romanesque" apse to the late 13th C has been met with scepticism. Author discusses use and misuse of the traditional source criticism, and attempts a revaluation of the declining market place Store Köpinge and the growing town of Ystad nearby.
A subgroup of patients suffering from primary Sjögren's syndrome (pSS) display unexplained low levels of complement components C3 and/or C4 which is associated with increased risk of non-Hodgkin's lymphoma. C4b-binding protein (C4BP) is a major fluid-phase complement inhibitor which can influence C4 and C3 levels. Therefore we analysed C4BP levels in the sera of patients with pSS to better underst
Sveriges judar är liksom andra svenskar i hög grad sekulariserade. Det är därför ingen överraskning att de mer ser judendomen som en nationell tillhörighet än som en religion. Det passar bra i det svenska samhället där man idag uppskattar multikulturalism och förhåller sig reserverat till svensk nationalism.
Abstract in Spanish Más atención se está dando a la necesidad de integrar la gestión del riesgo en el trabajo de desarrollo para poder reducir así la vulnerabilidad de los pobres que viven en áreas urbanas. Usando El Salvador como estudio de caso, este artículo analiza el proceso de integración en dos sectores de desarrollo: planificación urbana y vivienda social. El objetivo es identificar de qué
This article reviews the media studies section at the European Association of Japanese Studies conference in Ljubljana, Slovenia in July 2014. The conference marked the introduction of a separate media studies section at the EAJS, and the review comments favorably on the initiative as well as the overall outcome of the presentations and discussions in the section.
The aim of this study was to compare the frequency of human leukocyte antigen (HLA) genotypes in 1-18-year-old patients with type 1 diabetes newly diagnosed in 1986-1987 (n = 430), 1996-2000 (n = 342) and in 2003-2005 (n = 171). We tested the hypothesis that the HLA DQ genotype distribution changes over time. Swedish type 1 diabetes patients and controls were typed for HLA using polymerase chain r
Single-strand RNA-binding proteins (RBPs) are involved in many aspects of RNA metabolism and in the regulation of gene transcription. The RBP RBM3 was recently suggested to be a proto-oncogene in colorectal cancer; however, such a role has not been corroborated by previous studies in the colon or other tumor types, and the prognostic implications of tumor-specific RBM3 expression remain unclear. M
Abstract is not available
A mandatory National Premarital Thalassemia Screening Program was implemented in Jordan in 2004. This cross-sectional study aimed to assess the knowledge and attitudes of university students in North Jordan toward this program. Data was collected from 542 students from four universities (two public and two private universities) located in North Jordan, using a structured questionnaire. Results of
OBJECTIVES: To map out-patients with Chronic Obstructive Pulmonary Disease (COPD) with special reference to patients suffering from acute exacerbations, and to describe COPD health care structure and process in Swedish clinical practice in a real life setting. DESIGN: Retrospective, non-interventional, epidemiological survey. SETTING: 141 hospital based out patient clinics (OPC, n=30) and primary
Objectives: The aims of this study were to evaluate the community-based prevalence of atrial fibrillation (AF) in a western society using a geographically well-defined population in the northern part of Sweden as a reference and to estimate the proportion of patients eligible for oral anticoagulation (OAC) prophylactic therapy according to the stroke risk indices CHADS(2) and CHA(2) DS(2) -VASc. B
