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Metoder för bestämning av njurfunktion. Vad har vi att erbjuda idag?

Bestämning av njurens förmåga att koncentrera urin är sedan länge ett väsentligt prov på njurfunktion vid tubulointerstitiell njursjukdom, t ex kronisk pyelonefrit. Desmopressintest är det främsta, men inte enda, testet för att bedöma njurarnas koncentrationsförmåga. Isotopundersökningar av njurarna utmärks av att de är enkla och skonsamma för patienten och utan kontraindikationer. Ofta kompletter

Cancer risk in patients hospitalized with polymyalgia rheumatica and giant cell arteritis: a follow-up study in Sweden.

Objectives. Studies reporting cancer risk after PMR and GCA are few, but it remains an issue of both concern and controversy. We examined the overall and specific cancer risks among Swedish subjects following hospitalization for these diseases. Methods. PMR and GCA patients were identified from the Swedish Hospital Discharge Register and by linking them with the Cancer Registry. Follow-up of patie

Against Truthmaker Necessitarianism

This paper is an argument against Truthmaker Necessitarianism — the doctrine that the existence of a truthmaker necessitates the truth of the proposition it makes true. Armstrong’s sufficiency argument for necessitarianism is examined and shown to be question begging. It is then argued in detail that truthmaking is a matter of grounding truth and that grounding is a dependency relation that neithe

Long-term sustained autoimmune response to beta cell specific zinc transporter (ZnT8, W, R, Q) in young adult patients with preserved beta cell function at diagnosis of diabetes.

The aim of this study was to examine whether autoantibodies to: ZnT8-Tryptophan (ZnT8WA), ZnT8-Arginine (ZnT8RA) or ZnT8-Glutamine (ZnT8QA) correlated with C-peptide or other autoantibodies and to assess diagnostic sensitivity of ZnT8WRQA. Specimens from 270 newly diagnosed diabetic subjects (age 15--34 years) and after five 5 years duration of disease were examined. Four linear regression models

Impact of Human Papillomavirus (HPV)-6/11/16/18 Vaccine on All HPV-Associated Genital Diseases in Young Women.

Background The impact of the prophylactic vaccine against human papillomavirus (HPV) types 6, 11, 16, and 18 (HPV6/11/16/18) on all HPV-associated genital disease was investigated in a population that approximates sexually naive women in that they were "negative to 14 HPV types" and in a mixed population of HPV-exposed and -unexposed women (intention-to-treat group). Methods This analysis studied

Blood pressure and other metabolic syndrome factors and risk of brain tumour in the large population-based Me-Can cohort study.

OBJECTIVES:: Brain tumour has few established determinants. We assessed to which extent risk of brain tumour was related to metabolic syndrome factors in adults. METHODS:: In the Me-Can project, 580 000 individuals from Sweden, Austria, and Norway were followed for a median of 10 years after baseline measurement. Data on brain tumours were obtained from national cancer registries. The factors of m

Windstorms in Sweden - variations and impacts

Windstorms have caused severe damage on several occasions in Sweden during the last century. A general concern about future projections of climate extremes has raised questions on the variations and impacts of windstorms. The main objective with this work was to reach a deeper understanding of the variability and possible trends in ­windstorms, and related storm impacts in forests. This was achiev