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In several twin studies the relative contribution of genetic factors for personality traits has amounted to figures between 40 and 60%. In the present study we investigated to which degree polymorphisms in the 5-HTT and AP-2 beta genes are implicated in the neural processes involved in the formation of Temperament and Character traits, as estimated by Cloninger's TCI. Considering the background of
Multiple genetic loci confer susceptibility to breast and ovarian cancers. We have previously developed a model (BOADICEA) under which susceptibility to breast cancer is explained by mutations in BRCA1 and BRCA2, as well as by the joint multiplicative effects of many genes ( polygenic component). We have now updated BOADICEA using additional family data from two UK population-based studies of brea
The aim of our retrospective study was to determine the extent to which diffusion- and perfusion- weighted MRI combined with conventional MRI could be helpful in the evaluation of intensive care unit (ICU) patients who have unknown or unclear cerebral pathology underlying a serious clinical condition. Twenty-one ICU patients with disparity between the findings on brain CT scan and their clinical s
The development of bacterial vaginosis (BV) among women of childbearing age and the resulting quantitative and qualitative shift from normally occurring lactobacilli in the vagina to a mixture of mainly anaerobic bacteria is a microbiological and immunological enigma that so far has precluded the formulation of a unifying generally accepted theory on the aetiology and clinical course of BV This cr
Synthesis gas generated by the gasification of nitrogen-containing hydrocarbons will contain ammonia. This is a catalyst poison and elevated levels of nitrogen oxides (NOX) will be produced if the synthesis gas is combusted. This paper presents a study of the selective oxidation of ammonia in reducing environments. The concept is the same as in traditional selective catalytic reduction, where NOX
Electrical machines with distributed concentrated windings are challenging the selection of the soft magnetic materials due to stator design and power conversion efficiency. A shorter magnetisation path and relatively high magnetisation frequency establish a good potential for low permeability soft magnetic materials with low power losses in the core. The focus of this article is on the analysis o
Objective. Secondary hyperparathyroidism (SHPT) is a common problem among patients with chronic kidney disease (CKD) on haemodialysis. This study was conducted to assess the use, effectiveness and safety of intravenous paricalcitol in haemodialysis patients with various degrees of SHPT. Material and methods. This observational, multicentre, prospective study was conducted in 14 Swedish dialysis ce
During the latest early Campanian, a diverse vertebrate assemblage inhabited the shallow coastal waters of the Kristianstad Basin, southernmost Sweden. The taxon-rich fauna includes numerous species of sharks, rays, chimaeroids, bony fish, mosasaurs, plesiosaurs, aquatic birds, crocodiles, and turtles. Vertebrate fossils have been found at several localities within the basin, representing at least
The Qreiya section (Upper Egypt) contains a well-preserved record of the first radiation of the fasciculiths, an evolutionary event that affected the coccolithophores of the Order Discoasterales during the late Danian. At Qreiya it unfolds across the so-called Neo-Duwi Event. We describe the morphostructural changes that affected coccoliths and document a trend towards increased surface area of th
The potential microbial risk from using treated wastewater is a burning issue to be studied. In Sweden, only a small part of treated wastewater is reused directly, although water reuse could be beneficial. Disinfection is virtually never practised and no protective guidelines for water reuse are found in Sweden. Based on a 1 year monitoring programme of water quality, this paper estimates the micr
Abstract in Danish Anmeldelse i ’Fund og Forskning i det Kongelige Biblioteks Samlinger’, Bind 52, 2013, s. 462-66: Kristian Jensen: Revolution and the Antiquarian Book. Reshaping the Past, 1780-1815. Oxford University Press, 2011.
There is normally a mismatch between the current model of the plant and the model that was used for design. This mismatch is normally acceptable when the controller is designed. But if the process dynamics changes, the mismatch may be so large that the control behavior degrades and may be unacceptable. This paper evaluates the influences of model plant mismatch on the control loop behavior quantit
Background/Aim: Matrix metalloproteinases (MMPs) are involved in cancer biology. Expression of MMP7 (matrilysin) in colorectal cancer is associated with metastatic disease even though it is expressed in most tumour states. In the present study, our purpose was to analyze MMP7 in bowel and lymph nodes of different tumour stages and to evaluate its expression as a cancer biomarker. Patients and Meth
Rapid developments in infection biology create new and exciting options for individualized diagnostics and therapy. Such new practices are needed to improve patient survival and reduce morbidity. Molecular determinants of host resistance to infection are being characterized, making it possible to identify susceptible individuals and to predict their risk for future morbidity. Immunotherapy is emer
Atopic dermatitis (AD) affects adults and children and has a negative impact on quality of life. The present multicentre randomized double-blind controlled trial showed a barrier-improving cream (5% urea) to be superior to a reference cream in preventing eczema relapse in patients with AD (hazard ratio 0.634, p = 0.011). The risk of eczema relapse was reduced by 37% (95% confidence interval (95% C
Three dimensional domain swapping is one of the mechanisms involved in formation of insoluble aggregates of some amyloidogenic proteins. It has been proposed that proteins able to swap domains may share some common structural elements like conformationally constrained flexible turns/loops. We studied the role of loop L1 in the dimerization of human cystatin C using mutational analysis. Introductio
Nectar-feeding insects find flowers by 2 means, innate preferences and learned associations. When insects that hibernate as imagos (i.e., adults) start foraging after a long winter break, what guides them to new nectar rewards? Are innate preferences kept over such a long period? And are learned associations useful after long breaks? In a series of experiments I show here that, depending on previo
Recension av Therése Andersson (red.), Hjältar och Hjältinnor – föreställningar och gestaltningar från Eufemiavisor till Gösta Berlings saga.
