This thesis includes both experimental and clinical projects. The experimental studies investigate pathophysiological aspects of ventricular longitudinal function and therapeutic hypothermia during acute myocardial infarction (AMI). The clinical projects investigate the ability of ventricular longitudinal function variables to predict mortality and morbidity in patients with heart failure and redu

The pressing need to implement a more circular economy has led to advancements in the research field. In the spatial context, sharing spaces and access-over-ownership models have the potential to mitigate the detrimental environmental impacts of space use. This study aims to adapt an existing theoretical framework on access-based consumption to the spatial context. We utilise a qualitative case st

Smooth muscle participates in forming the wall of hollow organs, tracts, and blood vessels. Therefore, it plays a critical role in mediating vital functions in the body including regulation of blood pressure. In response to changes in the surrounding microenvironment, smooth muscle cells can modulate their phenotype and dedifferentiate from being quiescent contractile to a more proliferative and m

Lunds universitets remissyttrande över Karnit Flug och Patrick Honohans utvärdering av Riksbankens penningpolitik 2015-2020. Författat av Lars Jonung och Fredrik N G Andersson

In an explorative manner, this article uses a data-driven digital history set-up to focus on media political issues in Sweden during the second half of the twentieth century. By distant reading and topic modeling a dataset of 3100 Swedish Government Official Reports between 1945 and 1989—a corpus of some 87 million tokens—the article gives a new perspective of how the Swedish state examined and di

The purpose of this systematic review and meta-analysis is to determine the effect of lockdowns on COVID-19 mortality based on available empirical evidence. Lockdowns are defined as the imposition of at least one compulsory, non-pharmaceutical intervention (NPI). We employ a systematic search and screening procedure in which 19,646 studies are identified that could potentially address the purpose

When we bring to mind something we have seen before, our eyes spontaneously unfold in a sequential pattern strikingly similar to that made during the original encounter, even in the absence of supporting visual input. Oculomotor movements of the eye may then serve the opposite purpose of acquiring new visual information; they may serve as self-generated cues, pointing to stored memories. Over 50 y

Malignant brain tumors constitute a disaster in the lives of patients, either in the form of extremely low survival in glioblastoma, or the serious long-term adverse effects of therapy in medulloblastoma. These two tumor types represent the most common malignant brain entities in adults and children, respectively. Ever since the early 2000’s, no major improvement of patient outcomes occurred. Immu

BackgroundOvarian Cancer (OC) constitute the eighth most common cancers among women worldwide. Surgery remains the cornerstone in the management of OC. Intraoperative frozen section (FS) diagnosis is widely used to decide the surgery course. We aimed to assess the reliability of intraoperative FS diagnosis for treatment planning of patients with suspected OC from a multidisciplinary perspective. T

Strupfladder och flämtandning är några av tricken som fåglar tar till för att överleva höga temperaturer. I en allt varmare framtid kanske det inte räcker, skriver fågelforskarna Andreas Nord och Susan J. Cunningham.

The association between obesity and psychological stress is ambiguous. The aim is to investigate the association between metabolic syndrome (MetS) and body mass index (BMI), respectively, with occupational stress among Japanese office workers. The study is a secondary analysis of the intervention group from a randomized controlled trial. There are 167 participants included in the analysis. Occupat

This article presents and discusses the lessons learned from the monitoring of 25 integrated daylighting and electric lighting international case study projects. The case studies consist of real occupied buildings that have been monitored as part of the International Energy Agency (IEA) SHC Task 61/EBC Annex 77 Programme. The general goal of the case studies was to balance lighting energy use with

This report presents lessons learned from twenty-five worldwide real-life case studies implementing the integration of daylighting and electric lighting. The case studies were monitored with respect to energy use for lighting, visual performance, non-visual performance, and users’ satisfaction. The monitoring is largely based on field measurements, but it is also complemented with simulations and

This thesis investigates growth of III – V semiconductor nanowire (NW) arrays, in a core- branch architecture, with the aim to develop diffusion driven light emitting diodes (LED) on NWs. Diffusion driven LEDs are based on the concept of decoupling the active region from the p-n junction. The carriers are injected by diffusion in the active region, because of the bandgap difference between the pn

The stability of relaxation techniques has been studied for strongly coupled fluid-structure interaction (FSI) with application to a cantilever immersed in channel flow. The fluid is governed by Navier–Stokes equations for incompressible flow condition using turbulence modeling, and the solid is governed by the equation of motion with compressible material modeling. The applied kinematic descripti

A fluid–structure interaction (FSI) technique is applied to study the influence of hydrodynamic damping on the motion of a cantilever in a still tank. The FSI is performed by a partitioned technique, using the deal.II and OpenFOAM open-source packages. An incompressible flow solver is applied for the fluid and a compressible solver for the structure. The motion of the structure is generated by app