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A Four-kallikrein Panel and β-Microseminoprotein in Predicting High-grade Prostate Cancer on Biopsy : An Independent Replication from the Finnish Section of the European Randomized Study of Screening for Prostate Cancer

Background: A panel of four kallikrein markers (total, free, and intact prostate-specific antigen [PSA] and human kallikrein-related peptidase 2 [hK2]) improves predictive accuracy for Gleason score ≥7 (high-grade) prostate cancer among men biopsied for elevated PSA. A four-kallikrein panel model was originally developed and validated by the Dutch center of the European Randomized Study of Screeni

Improved neonatal outcome after active management of prolonged pregnancies beyond 41+2 weeks in nulliparous, but not among multiparous women

Introduction: Prolonged pregnancies are associated with adverse maternal and fetal outcome. In Sweden, no national guidelines exist for when to induce prolonged pregnancies. Material and methods: Singleton cephalic prolonged pregnancies (defined as ≥ 41+3 gestational weeks) during 2001-2013 (n = 199 770) were identified using the Swedish Medical Birth Register. The maternity units were divided int

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

Background - Genome-wide association studies have recently identified >400 loci that harbor DNA sequence variants that influence blood pressure (BP). Our earlier studies identified and validated 56 single nucleotide variants (SNVs) associated with BP from meta-analyses of exome chip genotype data. An additional 100 variants yielded suggestive evidence of association. Methods and Results - Here, we

Cardiovascular magnetic resonance to predict appropriate implantable cardioverter defibrillator therapy in ischemic and nonischemic cardiomyopathy patients using late gadolinium enhancement border zone comparison of four analysis methods

Background: Late gadolinium enhancement (LGE) border zone on cardiac magnetic resonance imaging has been proposed as an independent predictor of ventricular arrhythmias. The purpose was to determine whether size and heterogeneity of LGE predict appropriate implantable cardioverter defibrillator (ICD) therapy in ischemic cardiomyopathy (ICM) and nonischemic cardiomyopathy (NICM) patients and to eva

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Ovaj članak prezentira teoretski i metodološki model za analizu prepričanih iskustava bivših logoraša koji su kao civili odvedeni u koncentracione logore početkom rata u Bosni i Hercegovini 1990-tih godina. Cilj je analizirati prepričane rituale ratnog nasilja u koncentracionim logorima kao i identifikovati kako se počinioci ratnog nasilja i žrtve simbolično definiraju u pričama. Priče o nasilju u

Tillgång till snabb laboratorieanalys vid akut förgiftning ger bättre och säkrare vård - Men möjligheten till akuta prov­­svar varierar över landet

Access to rapid laboratory analytical services in cases of acute poisoning provides better and safer patient care The Swedish Poisons Information Centre, a nationwide 24/7 service to healthcare providers and the public, answers many questions about serious cases of acute poisoning. In some of these, prompt and proper treatment recommendations can be crucial for the clinical outcome. In cases where

Multi-dimensional grid-less estimation of saturated signals

This work proposes a multi-dimensional frequency and amplitude estimator tailored for noise corrupted signals that have been clipped. Formulated as a sparse reconstruction problem, the proposed algorithm estimates the signal parameters by solving an atomic norm minimization problem. The estimator also exploits the waveform information provided by the clipped samples, incorporated in the form of li

Take the Floor. Professional Communication Theoretically Contextualized

In Take the Floor I explored the conditions of communication inflected by habitus. Apart from Bourdieu’s definition of the notion, Rapport and Overing (2003: 2) emphasized those transposable dispositions which generate structured social practices. Understanding the conditions of habitus allows the generator of discourses, endowed with agency, to insert in them manipulative or propagandistic ingred

School Nurses' Experiences Working With Students With Mental Health Problems : A Qualitative Study

The aim was to describe school nurses' experiences working with students with mental health problems. In this inductive qualitative study, interviews were conducted with 14 school nurses in Sweden. The content analysis revealed three themes: (1) sense of worriedness about working with students with mental health problems, (2) taking care of students with mental health issues was an opportunity for

Prevalence and treatment of diabetes mellitus and hypertension among older adults with intellectual disability in comparison with the general population

BACKGROUND: Diabetes mellitus and hypertension are risk factors for cardiovascular disease, which is the most common cause of death in the world. People with intellectual disability (ID) have been reported to have high rates of both these disorders. The aim of this study was to describe and compare prevalence ratios of diabetes mellitus and hypertension between older adults with ID and their age p

Comparison of the FMEA and STPA safety analysis methods–a case study

As our society becomes more and more dependent on IT systems, failures of these systems can harm more and more people and organizations. Diligently performing risk and hazard analysis helps to minimize the potential harm of IT system failures on the society and increases the probability of their undisturbed operation. Risk and hazard analysis is an important activity for the development and operat

Pop Theory: The Architecture of Late Night Shopping

Inviting audiences into the late-night, precarious world of (photo)shopping, we explore the way in which the ghostly figures of the Photoshop world – its exhausted architects, indebted consumers, and the two-dimensional cut-outs that populate its spaces – are all put to use in a project of producing subjectivities through environments. Feminist critiques of visuality provide a basis in understandi

Corporate Taxation and Social Responsibility

This book advocates ethical self-restraint in the realm of corporate tax. It seeks to undermine, and ideally to remove, any self-serving rationalizations that may seductively encourage corporate executives to act without restraint. Nowhere is this more needed than in the world of business regulations, where corporate executives may be tempted to influence the formation, implementation, and reform