Hydroxyisohexyl 3-cyclohexene carboxaldehyde-known as Lyral (R): quantitative aspects and risk assessment of an important fragrance allergen
Hydroxyisohexyl 3-cyclohexene carboxaldehyde, also known as Lyral(R), is a fragrance ingredient identified as the cause of contact allergic reactions in 2-3% of eczema patients undergoing patch testing. Lyral(R) has been included in the standard patch test series in many clinics due to its importance as an allergen. It has been used without restrictions in cosmetic products, until now. In the pres