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The development of blood protein profiles in extremely preterm infants follows a stereotypic evolution pattern

BACKGROUND: Preterm birth is the leading cause of neonatal mortality and morbidity. Early diagnosis and interventions are critical to improving the clinical outcomes of extremely premature infants. Blood protein profiling during the first months of life in preterm infants can shed light on the role of early extrauterine development and provide an increased understanding of maturation after extreme

Ronneby PFAS Research Program (RPRP) : En sammanfattning av forskning 2014-2023

Det har nu gått snart tio år sedan det uppdagades att dricksvattnet i ett av vattenverken i Ronneby, som försörjde 1/3 av hushållen med dricksvatten, var mycket kraftigt förorenat av PFAS. Visserligen kunde rent vatten omedelbart kopplas in i vattenledningsnätet, men alla som under lång tid druckit det förorenade vattnet har fortfarande förhöjda halter av PFAS i kroppen och kommer att fortsätta ha

Indoor radon interval prediction in the Swedish building stock using machine learning

Indoor radon represents a health hazard for occupants. However, the indoor radon measurement rate is low in Sweden because of no mandatory requirements. Measuring indoor radon on an urban scale is complicated, machine learning exploiting existing data for pattern identification provides a cost-efficient approach to estimate indoor radon exposure in the building stock. Extreme gradient boosting (XG

Reducing water damage by using a holistic approach to costs, occurrence and solutions in buildings

Det rapporteras många fall och spenderas årligen stora mängder av resurser på vattenskador i byggnader i Sverige. Vattenskador som uppkommer på grund av läckage och utströmning av vatten från installationer så som tappvatten-, avlopp- och värmesystem, utrustning så som kylskåp, frysar och diskmaskiner samt läckande tätskikt i våtrum. Vattenskador från dessa system orsakar allvarliga problem i byggA large amount of water damage cases and resources are annually reported and spent on water damage in Sweden from cases occurring in buildings from building services such as tap water-, sewage, heating systems, household appliances such as refrigerators, freezers and dishwashers and inadequate waterproof membranes in wet rooms. These water damage cases in buildings cause several problems in the bu

Metallo-β-lactamase inhibitor phosphonamidate monoesters

Being the second leading cause of death and the leading cause of disability-adjusted life years worldwide, infectious diseases remain─contrary to earlier predictions─a major consideration for the public health of the 21st century. Resistance development of microbes to antimicrobial drugs constitutes a large part of this devastating problem. The most widely spread mechanism of bacterial resistance

Pictures and spoken descriptions elicit similar eye movements during mental imagery, both in light and in complete darkness

This study provides evidence that eye movements reflect the positions of objects while participants listen to a spoken description, retell a previously heard spoken description, and describe a previously seen picture. This effect is equally strong in retelling from memory, irrespective of whether the original elicitation was spoken or visual. In addition, this effect occurs both while watching a b

Costly steroids: egg testosterone modulates nestling metabolic rate in the zebra finch

The transfer of non-genetic resources from mother to the offspring often has considerable consequences for offspring performance. In birds, maternally derived hormones are known to influence a variety of morphological, physiological and behavioural traits in the chick. So far, the range of these hormonal effects involves benefits in terms of enhanced growth and competitive ability as well as costs

Changes in structural attributes of plant communities along disturbance gradients in a dry deciduous forest of Western Ghats, India

Changes in tree and understory plant diversity and community composition in two sites at different disturbance levels were studied on the Anaikatty hills, Western Ghats. Systematic sampling using small scale permanent quadrates (50 x 20 m for trees, 5 x 5 m for shrubs/saplings, 1 x 1 m for herbs/seedlings) enumerated 3,376 individuals of trees (106 species), 8,599 of individuals shrubs (122 specie

Prompt Proton Decay in the Vicinity of 56Ni

A new decay mode, the so called prompt proton decay, was discovered in 1998. It has since proven to be an important decay mechanism for several neutron deficient nuclei in the A similar to 60 region. To measure with high accuracy the energies and angular distributions of these protons, a state-of-the-art charged particle detector - LuWuSiA - was developed. It was first utilized during a fusion-eva

Artificial selection for increased comb size and its effects on other sexual characters and viability in gallus-domesticus (the domestic chicken)

The expression of secondary ornaments is often positively correlated with the bearer's condition. So far no study has reported on consequences of directional selection on male sexual ornaments in birds, i.e. it is unknown to what extent male sexual traits are genetically correlated and whether selection for secondary ornaments affects viability. In this study we estimate phenotypic and genotypic p

Evolution of free, complexed, and total serum prostate-specific antigen and their ratios during 1 year of follow-up of men with febrile urinary tract infection

Objectives. To determine the serum values of free, complexed, and total prostate-specific antigen (PSA) and their ratios in men with febrile urinary tract infection (UTI) during 1 year of follow-up. Methods. A total of 54 men were prospectively enrolled in the study, and serum samples were obtained at the acute stage of the UTI and after 1, 3, 6, and 12 months. Results. Most men had a rise (median

Nanoelectrochemical transducers for (bio-) chemical sensor applications fabricated by nanoimprint lithography

Nanometer-structured transducers for commercial use in pharmaceutical, medical or (bio-) chemical analysis have so far been hardly accessible since they could not be produced by parallel lithography techniques at reasonable costs. We introduce here a method on. how to fabricate nanometer-structured interdigitated array electrodes including interconnections and bond pads in the micrometer range in

Association of metabolic gene polymorphisms with tobacco consumption in healthy controls

Polymorphisms in genes that encode for metabolic enzymes have been associated with variations in enzyme activity between individuals. Such variations could be associated with differences in individual exposure to carcinogens that are metabolized by these genes. In this study, we examine the association between polymorphisms in several metabolic genes and the consumption of tobacco in a large sampl

Effects of animal selection on milk composition and processability.

One goal of animal breeding is to increase the economic output through increased production, improved milk quality, and cow health. The objective of this study was to evaluate genetic progress in relation to milk composition, processability, and yield as a correlated response to selection for the Swedish breeding objective. Dairy cows with high genetic merit, classified as elite dairy cows, of the

Enrichment of phosphoproteins and phosphopeptide derivatization identify universal stress proteins in elicitor-treated Arabidopsis

Protein phosphorylation is a key biological process that regulates reactions involved in plant-microbe interactions. The phosphorylated form of a protein often represents only a small fraction of the total population and can be problematic to analyze in a mass spectrometer. We demonstrate how a titanium dioxide (TiO2) resin can be employed for the enrichment of phosphoproteins, as well as a method

Optimal recall length in survey design

Self-reported data collected Via Surveys are a key input into a wide range of research conducted by economists. It is well known that Such data are subject to measurement error that arises when respondents are asked to recall past utilisation. Survey designers Must determine the length of the recall period and face a trade-off as increasing the recall period provides more information, but increase