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Nine patients with spondylarthropathy (SpA) (6 with ankylosing spondylitis and 3 with psoriatic arthritis) who had not responded properly to conventional DMARD therapy were treated with 3 infusions (at 0, 2 and 6 weeks) of the TNF alpha inhibitor infliximab (3 mg/kg), in combination with methotrexate. To measure the effect of treatment, patients were evaluated before as well as 8 and 12 weeks afte
A simple and inexpensive amperometric biosensor for formate detection was obtained by immobilization of for-mate dehydrogenase (FDH) on graphite powder, modified with a new phenothiazine derivative (DDDP; 16H, 18H-dibenzo[c,l]-7,9-dithia-16,18-diazapentacene). Two different enzyme environments were used: FDH was adsorbed on DDDP-modified graphite powder in the presence of polyethylenimine (PEI) as
A more than 40-year-long process came to an end when relations between the Church of Sweden and the state were formally changed in the year 2000. Social Democrats and Liberals had taken the initiative in the 1950s. Several proposals for disestablishment were put forward in the 1970s, but none of them. achieve political consensus. In addition, the representatives for all the political parties on th
This study aims to investigate the possibility of implementing serial autoradiography using a silicon strip detector as an imaging modality in pre-clinical radionuclide therapy research, in order to study the effect of non-uniform uptake on absorbed dose distribution and biological response. Tumor tissues expressing CD20 (B-cell lymphoma) or carcinoembryonic antigen (CEA; colorectal cancer) were e
Inclusive production cross sections are measured in deep inelastic scattering at HERA for meson states composed of a charm quark and a light antiquark or the charge conjugate. The measurements cover the kinematic region of photon virtuality 2 < Q(2) < 100 GeV2, inelasticity 0.05 < y < 0.7, D meson transverse momenta p(t)( D) greater than or equal to 2.5 GeV and pseudorapidity |eta( D)| less than o
Programming languages are the main tools used to describe models of the real world and algorithms which manipulate these models. Over time much effort has been devoted to the task of making programming languages more high-level by enhancing their expressiveness, bringing it closer to the way the programmer thinks and reasons. The development of object-oriented programming languages is one importan
Aim The aim of this work was to estimate C sequestration rates in the organic matter layer in Swedish forests. Location The region encompassed the forested area (23 x 10(6) ha) of Sweden ranging from about 55degrees N to 69degrees N. Methods We used the concept of limit values to estimate recalcitrant litter remains, and combined it with amount of litter fall. Four groups of tree species were iden
The diurnal hummingbird hawkmoth Macroglossum stellatarum can learn the achromatic (intensity-related) and the chromatic (wavelength-related) aspect of a spectral colour. Free-flying moths learn to discriminate two colours differing in the chromatic aspect of colour fast and with high precision. In contrast, they learn the discrimination of two stimuli differing in the achromatic aspect more slowl
Supported phospholipid bilayers (SPBs) have emerged as important model systems for studies of the natural cell membrane and its components, which are essential for the integrity and function of cells in all living organisms, and also constitute common targets for therapeutic drugs and in disease diagnosis. However, the preferential occurrence of spontaneous SPB formation on silicon-based substrate
The effects of whole-body exposure to ambient temperatures of -15 degrees C and 23 degrees C on selected performance-related physiological variables were investigated in elite nonasthmatic cross-country skiers. At an ambient temperature of -15 degrees C we also studied the effects of the selective beta2-adrenergic agonist Salbutamol (0.4 mg x 3) which was administered 10 min before the exercise te
Popular Abstract in Swedish Vad har den slaviskt inspirerade östersjökeramiken som arkeologer finner i Skandinavien med slaver att göra? Levde de som gäster i huset? Vikingen och hanseaten har sedan länge sina platser inbokade på den historiska scenen. Under äldre medeltid rörde sig även andra aktörer över Östersjöns vatten. Främmande gäster besökte och bosatte sig i Skandinavien. Bland dem fanns Scholarly texts on Slavic-Scandinavian relations have concentrated on two main areas of interest. During the Viking Age the economic and social contacts between the lake Mälaren district and Rus’ were extensive. However, at the beginning of the Middle Ages, political antagonism between the two expanding realms of the Svear and the Novgorodians is noticeable. In southern Scandinavia, the hostility
Thin layers of GaxIn1-xP grown on top of self-assembled InP quantum dots has been studied using transmission electron microscopy (TEM), scanning tunneling microscopy (STM), and low-temperature scanning tunneling luminescence (STL). STM reveals that the overgrowth is highly uneven, in which elongated GaxIn1-xP islands covering the dots are formed. TEM and high-spatial-resolution STL show that the q
The inclusive e(+)p single and double differential cross sections for neutral and charged current processes axe measured with the H1 detector at HERA. The data were taken in 1999 and 2000 at a centre-of-mass energy of roots = 319 GeV and correspond to an integrated luminosity of 65.2 pb(-1). The cross sections are measured in the range of four-momentum transfer squared Q(2) between 100 and 30 000
Popular Abstract in Swedish Den nuvarande teknologin inom förbränningsmotorer har möjligheten att hantera den alltmer strikta myndighetskraven på förbränningsmotorn. Emellertid de nödvändiga tekniska lösningarna som krävs är dyra och alltmer tekniskt krävande. En möjlig väg mot enklare efterbehandlingssystem är anvädningen av Homogen Kompressions Antändning (Eng: HCCI) motor cykeln. Den huvudsaklThe current technology within combustion engines have the possibility of handling the more stringent legislative demands on combustion engines. However the required solutions are getting more expensive and technically challenging. One possible way towards a more simple exhaust aftertreatment system is the use of the Homogeneous Charge Compression Ignition (HCCI) engine cycle. The main advantage o
Antithyroid treatment for Graves' hyperthyroidism restores euthyroidism clinically within 1-2 months, but it is well known that TSH levels can remain suppressed for many months despite normal free T(4) and T(3) levels. This has been attributed to a delayed recovery of the pituitary-thyroid axis. However, we recently showed that the pituitary contains a TSH receptor through which TSH secretion may
Popular Abstract in Swedish I denna avhandling har användbarheten av Virtual Reality (VR) utvecklats och undersökts för två användningsområden: participatorisk design av arbetsplatser och hjärnskaderehabilitering. Inom det första användningsområdet används VR tillsammans med fullskalemodellering, drama och demokratisk mötesteknik i en Visualiseringsverkstad. Denna arbetsmetod har utvecklats och tIn this thesis, the usability of Virtual Reality (VR) has been investigated and developed within two applications: participatory design of workplaces and brain injury rehabilitation. In the first application, VR is used in combination with full scale modelling, drama and democratic meetings in an Envisionment Workshop. This workshop has been developed and tested through several real workplace int
