Interactions between immune cells such as T cells and antigen-presenting cells (APCs) are integral for mounting an adaptive immune response. The interaction between the T cell receptor (TCR) and the antigen-presenting major histocompatibility complex (pMHC) on a contacting T cell and APC, is widely accepted to be the key interaction. If the interaction is favourable, then T cell activation occurs.

The atmospheres of ultra hot Jupiters (UHJs) are prime targets for the detection of molecules and atoms at both low and high spectral resolution. We study the atmospheres of the UHJs WASP-121b and WASP-189b by performing 3D general circulation models (GCMs) of these planets using high temperature correlated-k opacity schemes with ultra-violet (UV) absorbing species included. The GCM results are th

Nanostraw substrates have great potential for achieving minimally invasive cell transfection. Cells located on the nanostraw substrate are subjected to mild DC electric pulses applied across the nanostraw substrate, which open pores in the cell membrane on top of the nanostraws and drives charged cargo through these pores via electrophoresis. However, with this method, the current may leak through

This article studies the potential combination of direct ground cooling (DGC) with district heating (DH) and ground source heat pumps (GSHP) to compare the required borehole depths and needed drilling areas. It also examines two different borehole sizing approaches to optimize investment costs and drilling areas. The results show that the required borehole depths in most cases are shorter for the

Background Joint damage in rheumatoid arthritis (RA) remains a significant problem. Identification of biomarkers associated with joint destruction can improve our understanding of underlying disease processes and future management.Objectives To evaluate inflammatory proteins as potential predictors of radiographic progression of joint damage.Methods Consecutive early RA patients (symptom duration

Background/Purpose: There has been increasing interest in diet as a factor that may contribute to the development of rheumatoid arthritis (RA). There is limited and somewhat contradictory information on the impact of dairy products in this context. The purpose of this study was to investigate the relation between intake of various dairy products and the risk of RA in a nested case-control study.Me

Background: Joint damage in rheumatoid arthritis (RA) includes erosions and joint space narrowing (JSN). Predictors of these processes, and the underlying mechanisms, require further study1.Objectives: To investigate the relation between patient characteristics at RA diagnosis and progression of erosions and JSN, over 5 years. Methods: Consecutive early RA patients (symptom duration Results: 233 e

Background/Purpose:Rheumatoid arthritis (RA) is associated with an increased rate of cardiovascular (CV) disease. Systemic inflammation has been implicated as a key factor behind CV comorbidity in RA. The objective of this study was to investigate the impact of disease activity and inflammation over the first two years on the risk of subsequent CV events in patients with early RA.Methods:An incept

Today, the advances in airborne LIDAR technology provide high-resolution datasets that allow specialists to detect archaeological features hidden under wooded areas more efficiently. Still, the complexity and large scale of these datasets require automated analysis. In this respect, artificial intelligence (AI)-based analysis has recently created an alternative approach for interpreting remote sen

Festskriftsbidrag till Antje Jackelén

This open-access book surveys how digital technology can contribute effectively to improving our understanding of the past, through a sensory engagement based on the evidence of material culture. In particular, it encourages specialists to consider senses and human agency as important factors in studying ancient space, while recognising the role played by digital tools in enhancing a human-centred

The book contains a summary presentation of the Swedish legal system, written by leading Swedish experts in their respective legal fields. It is intended to be used by foreign law students participating in introductory courses in Swedish law, foreign legal professionals looking for fundamental information about the Swedish approach to a particular legal problem and Swedish lawyers when communicati

Advanced maternal age at birth is considered a risk factor for adverse birth outcomes. A recent study applying a sibling design has shown, however, that the association might be confounded by unobserved maternal characteristics. Methods: Using total population register data on all live singleton births during the period 1999-2012 in Denmark (N = 580-133; 90% population coverage), Norway (N = 540-8

Objective: Peritraumatic dissociation (PD) and coping strategies (CS) around the time of trauma are significantpredictors of acute and long-term posttraumatic symptomatology (PTS), but it is unclear howthey relate to each other. The aim of this study was to examine their association using a nationwide, representativesample following the September 11 attacks in the United States (N = 3,134). Method

The chapter examines the role of indirect review of administrative action in Swedish law. A general description of the overall structure of the Swedish system for judicial review of administrative action is followed by a discussion about the administrative measures that cannot be reviewed in a direct review. The chapter then focuses specifically on the phenomenon of indirect judicial review in relThe chapter examines the role of indirect review of administrative action in Swedish law. A general description of the overall structure of the Swedish system for judicial review of administrative action is followed by a discussion about the administrative measures that cannot be reviewed in a direct review. The chapter then focuses specifically on the phenomenon of indirect judicial review in rel

This paper reports on the results of thermal response tests conducted with laboratory-grade instrumentation and equipmentfor a borehole system consisting of nine groundwater-filled boreholes, each about 80 m (262 ft) deep. The ground thermalproperties, including the undisturbed ground temperature, the thermal conductivity and the borehole thermal resistance, aredetermined for each of the nine bore

Lapptestning med palladium och aluminium (Swedish popular science summary)Lapptestning är standardmetoden för påvisning av kontaktallergi. Metoden har använts i över 100 år och utvecklas fortfarande. På 80-talet började flera kliniker i USA och Europa, inklusive Yrkes-och miljödermatologisk avdelning i Malmö, att lapptesta med palladiumklorid for att kunna påvisa palladiumallergi. Palladium är en AbstractThe aim of this thesis was to investigate the prevalence and significance of contact allergy to palladium from a Swedish perspective. Our initial findings made it necessary to also explore the importance of the metal aluminium used in test chamber systems and the effect of aluminium chloride (Al-Cl) in patch test preparations. A retrospective study (study I), with 18,306 patch test results

Post-flame sulfation of gaseous sodium hydroxide (NaOH) and sodium chloride (NaCl) was investigated with optical in situ measurements at 850 to 1475 °C. A multi-jet burner was used to generate well-controlled combustion environments. The multi-jet burner also enabled the separate feeding of the sodium species and SO2 to the combustion environment where the sulfation reactions occurred. Concentrati

Turbulent premixed flames subjected to extreme levels of turbulence exhibit reaction zone broadening and thinning. Instantaneous flame structures visualized using advanced laser diagnostic methods have shown significantly different behaviours of flame/turbulence interaction in jet flames stabilized on burners of different sizes. This paper aims to reconcile the controversy about flame broadening o