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Interleukin-1 (IL-1) is a major mediator of inflammation that exerts its biological activities through the IL-1 type I receptor (IL-1RI). The body weights of IL-1RI(-/-) mice of both sexes started to deviate from those of wild-type mice at 5-6 months of age and were 20% higher at 9 months of age. Visceral and subcutaneous fat mass, measured by dual-energy X-ray absorptiometry and magnetic resonanc

Rheumatoid arthritis is a disease of unknown aetiology. Twin studies indicate the importance of genetic as well as environmental factors. 1 In terms of environmental factors, few risk factors are well established, and, in practice, rheumatoid arthritis cannot be attributed to any specific exposure. 2 Descriptive studies imply a birth cohort effect in the incidence of rheumatoid arthritis. 3 4 We a

Single film examinations (iodine and/or barium) were reviewed in 28 patients who had undergone surgery on the cricopharyngeal muscle due to Zenker diverticula (24 patients), cricopharyngeal muscle incoordination (3 patients) and pharyngoesophageal web (one patient). All patients had had a myotomy which included the cricopharyngeal muscle and up to 3 cm of the cervical esophagus. Lateral and anteri

The somatic cell count (SCC) in bovine milk is an indicator of udder health and milk quality. Individual cell populations, i.e., macrophages, lymphocytes and polymorphonuclear neutrophils, were identified and their relationship to milk components such as acute-phase proteins (serum amyloid A (SAA) and alpha(1)-acid glycoprotein), lactic acid and lactoferrin (LF), as well as protein, fat and lactos

Beim Fahrradfahren arbeitet der Mensch als Regler. Das wird beim Balancieren des Fahrrades besonders offensichtlich, denn das Fahrrad ist instabil. In diesem Beitrag wird untersucht, unter welchen Bedingungen es möglich ist, das Fahrrad mit einem so einfachen Reglergesetz zu balancieren, dass Menschen dieses Reglergesetz ohne Mühe realisieren können. Dabei wird nicht nur die jedem Radfahrer bekann

Low body mass index (BMI) is a well-documented risk factor for future fracture. The aim of this study was to quantify this effect and to explore the association of BMI with fracture risk in relation to age, gender and bone mineral density (BMD) from an international perspective using worldwide data. We studied individual participant data from almost 60,000 men and women from 12 prospective populat

While the themes of fragmentation and insufficient coherence dominated discussions in the field of media and communication studies a decade ago, today they seem less urgent, even if at times still problematic. In terms of theory, the field is well served by its permeable boundaries, since much of its theory is 'imported'. Moreover, theory needs nondoctrinaire critical stances to address the distre

Diabasbrottet, selected by the International Subcommisson on Ordovician Stratigraphy and in 2002 ratified by the International Commission on Stratigraphy as the GSSP of the Second (Upper) Stage of the Lower Ordovician, is located on the Hunneberg Mountain in southwestern Sweden. The stratigraphic succession represents an outer shelf environment near the Baltic Shield margin. The shale-dominated, b

System identification of linear multivariable dy-namic models based on discrete-time data can be performed using a algorithm combining linear regression and LQG-balanced model reduction. The approach is applicable also to unstable system dynamics and it provides balanced models for optimal linear prediction and control.

The mass transfer aspects of synthetic dryer fabrics used in multi-cylinder paper dryers were investigated both experimentally and computationally. Experiments were performed in a convective dryer to determine which characteristics of the fabric are instrumental in controlling the drying rate. Results obtained from twelve different fabrics showed that neither the permeability nor the porosity of t

OBJECTIVE: Despite a change of fetal physiologic and biochemical functions with gestational age, stationary umbilical cord acid-base reference values are used as measures of obstetric care quality. The aim of this study was to assess the risk of low Apgar score relative to low pH when using stationary versus gestational age-adjusted reference values. METHODS: Umbilical artery pH was determined in

Popular Abstract in Swedish Astma är en sjukdom som karakteriseras av upprepade anfall av andningssvårigheter, orsakade av kramp, slemhinnesvullnad och segt sekret i luftvägarna. Den finns beskriven i texter redan från det antika Grekland och rapporteras idag vara en sjukdom med utbredning över hela vårt klot. Astma är den vanligaste kroniska sjukdomen bland barn och är oavsett ålder den vanligastAsthma is a chronic disorder of the lower airways, characterized by inflammation and hyperreactivity. Pro-inflammatory cytokines like tumour necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) are known to play important roles in the pathogenesis, but our knowledge how these cytokines contribute to the development of airway hyperreactivity is limited. The aims of the present study