We discuss different aspects of unconditional two-locus nonparametric linkage (NPL) analysis with special emphasis on gene-gene interaction. We interpret this as identical-by-descent (IBD) sharing correlation between two disease loci both having marginal effect. We relate this to the concept of two-locus NPL score functions, the possible importance of using a composite rather than a simple null hy

Background The potential mutagenic effects of cancer therapies and the growing number of young male cancer survivors have given rise to concern about the health of their offspring. Methods We identified all singleton children born alive in Denmark between 1994 and 2004 and in Sweden between 1994 and 2005 (n = 1 777 765). Of the 8670 children with a paternal history of cancer, 8162 were conceived n

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BACKGROUND: The aim of this study was to investigate the association between factors in metabolic syndrome (MetS; single and combined) and the risk of pancreatic cancer. METHODS: The Metabolic Syndrome and Cancer Project is a pooled cohort containing data on body mass index, blood pressure, and blood levels of glucose, cholesterol, and triglycerides. During follow-up, 862 individuals were diagnose

Aims: To examine whether the decrease in the mean breath alcohol concentration (BrAC) and the rowdy social atmosphere reported after one month remained stable in the five-month assessment. Design: Randomized controlled trial. Setting: University bars. Participants: The five-month assessment was based on 596 students visiting student bars during ordinary pub evenings. Intervention: Bartenders (n =

To cite this article: Schlehofer B, Siegmund B, Linseisen J, Schüz J, Rohrmann S, Becker S, Michaud D, Melin B, Bas Bueno-de-Mesquita H, Peeters PHM, Vineis P, Tjonneland A, Olsen A, Overvad K, Romieu I, Boeing H, Aleksandrova K, Trichopoulou A, Bamia C, Lagiou P, Sacerdote C, Palli D, Panico S, Sieri S, Tumino R, Sanchez M-J, Rodriguez L, Dorronsoro M, Duell EJ, Chirlaque M-D, Barricarte A, Borgq

Abstract in German Alles in allem eine Anthologie, die in Detailfragen durchaus aktuellste Forschungsergebnisse vorweisen kann, aber von einer annähernd vollständigen Forschungsübersicht zur Thematik „Musik und Nationalsozialismus“ weit entfernt ist, und auch nicht mit den in Monographien vorgelegten Forschungsergebnissen der Autorinnen und Autoren mithalten kann.

The moisture permeability of hardened cement paste is normally not a constant, because it depends on both the porosity and the relative humidity (RH) in the pores of the cement paste when RH exceeds approximately 60 to 70%. The measured results show a strong relationship between the porosity of the cement paste and the moisture permeability.

We study the phase diagrams of the s-band and d-band Hubbard model in two dimensions including electron correlations. While the ferromagnetic instability in the s-band case occurs only near the Van Hove singularity, ferromagnetism is more stable in the d-band model, and the values of the Stoner parameters in transition metals are reduced below their LDA values.(14 refs)

Endovascular treatment of aorto-iliac occlusive disease (AIOD) is well established, but to maintain long-term patency, secondary interventions are common. Multiple stents and iliac artery tortuosity often make it difficult to evaluate stent compression intra-operatively and this might be a cause for later failure. Completion angiography (CA) and pressure gradient (PG) measurement are often used to